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The map label for this gene is arcB [H]

Identifier: 152976536

GI number: 152976536

Start: 2900897

End: 2901847

Strand: Reverse

Name: arcB [H]

Synonym: Bcer98_2825

Alternate gene names: 152976536

Gene position: 2901847-2900897 (Counterclockwise)

Preceding gene: 152976537

Following gene: 152976535

Centisome position: 71.0

GC content: 37.22

Gene sequence:

>951_bases
ATGTCAATTGTACAAGTGCCGAAATTACAAACGAAACATGTATTAACTTTGGAAGAATTAACGCAAGAAGAAATCATTTC
TGTAATTAAGTTTGCCATATATTTAAAAAAGAATAAACATGAACCTTTTTTAAAGGGAAAAATATTAGGGCTCATTTTTG
ATAAACAGTCTACACGTACACGTGTCTCCTTTGAAGCAGGAATGATGCAACTCGGTGGACATGGAATGTTTTTAAGTGGG
AAAGACATGCAACTTGGACGAGGGGAAAGTATTGCTGATACGGCAAAAGTTTTATCAAAATATATTGATGGGATTATGAT
TCGTACCTTTTCACATGCAGATGTTGAAGAACTTGCAAAAAAGGCTAACATTCCTGTTATTAATGGATTAACAGATGACC
ACCATCCATGTCAAGCACTGGCCGACTTAATGACAATTTATGAAGAAGTTCGTACATTTAAAGGCATAAAACTAGCTTAT
ATAGGTGATGGAAATAACGTATGCCATTCTTTATTAGTAGCGAGTGCAAAAGTAGGAATGGATATGGCAGTCGCAACACC
AAGAGGTTATGAGCCAAACGGGAGAATGATACAAAAAGCATTAGAAATTGCTGAAGAGACTGGAGCAAAACTTGAATTTT
TCCATGCCCCACAGCTAGCAGTAGCAGAAGCTGATTTTGTTTATACTGATGTTTGGATGAGTATGGGGCAAGAAGGCGCT
CAAGAAAAAAAGGTAATATTTCAGCCATTTCAAATCAATTGTGAACTTGTCCAATATGCAAAGAAGACATATCGTTTTTT
ACATTGTTTACCTGCACACCGCGGGGAAGAAGTGACGAGTGAAATCATCGATGGTATGCACTCGATTGTTTTTACGCAAG
CGGAGAATCGTTTGCATGCTCAGAAGGCTTTACTAGTAAGTATATTCGAGAACATGAAAGAACCTTCCTAG

Upstream 100 bases:

>100_bases
ACCACTCATTGTTACAAAGGAAGAGTTAGAACAAGCCATATACATGATCAAAAAAGTAATCTGTACAAAAATATTACCAT
CTATATAAGGGGGAAATACG

Downstream 100 bases:

>100_bases
CATGGGAGGGTTTTTGTGTCATTTTAAAAAAATATAAAGTATGTTAAAGGGGAAATAATCGAACAAATAAGGAACAAAAC
ATGTAAGCTCGTTTTGTTCG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSIVQVPKLQTKHVLTLEELTQEEIISVIKFAIYLKKNKHEPFLKGKILGLIFDKQSTRTRVSFEAGMMQLGGHGMFLSG
KDMQLGRGESIADTAKVLSKYIDGIMIRTFSHADVEELAKKANIPVINGLTDDHHPCQALADLMTIYEEVRTFKGIKLAY
IGDGNNVCHSLLVASAKVGMDMAVATPRGYEPNGRMIQKALEIAEETGAKLEFFHAPQLAVAEADFVYTDVWMSMGQEGA
QEKKVIFQPFQINCELVQYAKKTYRFLHCLPAHRGEEVTSEIIDGMHSIVFTQAENRLHAQKALLVSIFENMKEPS

Sequences:

>Translated_316_residues
MSIVQVPKLQTKHVLTLEELTQEEIISVIKFAIYLKKNKHEPFLKGKILGLIFDKQSTRTRVSFEAGMMQLGGHGMFLSG
KDMQLGRGESIADTAKVLSKYIDGIMIRTFSHADVEELAKKANIPVINGLTDDHHPCQALADLMTIYEEVRTFKGIKLAY
IGDGNNVCHSLLVASAKVGMDMAVATPRGYEPNGRMIQKALEIAEETGAKLEFFHAPQLAVAEADFVYTDVWMSMGQEGA
QEKKVIFQPFQINCELVQYAKKTYRFLHCLPAHRGEEVTSEIIDGMHSIVFTQAENRLHAQKALLVSIFENMKEPS
>Mature_315_residues
SIVQVPKLQTKHVLTLEELTQEEIISVIKFAIYLKKNKHEPFLKGKILGLIFDKQSTRTRVSFEAGMMQLGGHGMFLSGK
DMQLGRGESIADTAKVLSKYIDGIMIRTFSHADVEELAKKANIPVINGLTDDHHPCQALADLMTIYEEVRTFKGIKLAYI
GDGNNVCHSLLVASAKVGMDMAVATPRGYEPNGRMIQKALEIAEETGAKLEFFHAPQLAVAEADFVYTDVWMSMGQEGAQ
EKKVIFQPFQINCELVQYAKKTYRFLHCLPAHRGEEVTSEIIDGMHSIVFTQAENRLHAQKALLVSIFENMKEPS

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=310, Percent_Identity=41.9354838709677, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI18105007, Length=310, Percent_Identity=29.3548387096774, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=37.7300613496933, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1786469, Length=329, Percent_Identity=37.3860182370821, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI2367364, Length=311, Percent_Identity=30.8681672025724, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI48994908, Length=360, Percent_Identity=25.2777777777778, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204318, Length=172, Percent_Identity=33.1395348837209, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322373, Length=333, Percent_Identity=38.4384384384384, Blast_Score=225, Evalue=8e-60,
Organism=Saccharomyces cerevisiae, GI6322331, Length=272, Percent_Identity=28.6764705882353, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24642586, Length=308, Percent_Identity=27.5974025974026, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35345; Mature: 35213

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVQVPKLQTKHVLTLEELTQEEIISVIKFAIYLKKNKHEPFLKGKILGLIFDKQSTRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEEEEECCCCCCE
RVSFEAGMMQLGGHGMFLSGKDMQLGRGESIADTAKVLSKYIDGIMIRTFSHADVEELAK
EEEHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
KANIPVINGLTDDHHPCQALADLMTIYEEVRTFKGIKLAYIGDGNNVCHSLLVASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCC
DMAVATPRGYEPNGRMIQKALEIAEETGAKLEFFHAPQLAVAEADFVYTDVWMSMGQEGA
CEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCC
QEKKVIFQPFQINCELVQYAKKTYRFLHCLPAHRGEEVTSEIIDGMHSIVFTQAENRLHA
CCCCEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKALLVSIFENMKEPS
HHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIVQVPKLQTKHVLTLEELTQEEIISVIKFAIYLKKNKHEPFLKGKILGLIFDKQSTRT
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCEEEEEEECCCCCCE
RVSFEAGMMQLGGHGMFLSGKDMQLGRGESIADTAKVLSKYIDGIMIRTFSHADVEELAK
EEEHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHH
KANIPVINGLTDDHHPCQALADLMTIYEEVRTFKGIKLAYIGDGNNVCHSLLVASAKVGM
HCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCC
DMAVATPRGYEPNGRMIQKALEIAEETGAKLEFFHAPQLAVAEADFVYTDVWMSMGQEGA
CEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHHCCCCC
QEKKVIFQPFQINCELVQYAKKTYRFLHCLPAHRGEEVTSEIIDGMHSIVFTQAENRLHA
CCCCEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QKALLVSIFENMKEPS
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA