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The map label for this gene is mtnU [H]

Identifier: 152976444

GI number: 152976444

Start: 2818243

End: 2819022

Strand: Reverse

Name: mtnU [H]

Synonym: Bcer98_2733

Alternate gene names: 152976444

Gene position: 2819022-2818243 (Counterclockwise)

Preceding gene: 152976451

Following gene: 152976443

Centisome position: 68.97

GC content: 38.33

Gene sequence:

>780_bases
ATGAAGGTCGCATGTATTCAAATGGATATTGTTTTTGGTGAGGTAACTTTAAATACAGAGCACGCAGAGAAAAAAATAGA
AGAGGCAATGAAAGTGAACCCAGATGTAATCGTATTGCCTGAACTTTGGACAACAGGATATGATTTGAAGCGACTTCCTG
AAATTTCAGATAAGGATGGAAAACAAACAAAAGAAGTGCTTTCAAAATGGGCAAAAGAGTTTAGCGTGAACATTGTCGGT
GGTTCTGTTGCAAAGCAGACAGAGAAAGGTGTTACAAATACGATGTATATTATGGATCGCCAAGGAAACGTACAACATGA
ATATAGCAAAGTGCACTTGTTTCAGTTAATGAATGAACATAAGTATTTAATAGCAGGACATGAAACAGGAGAATTTACTT
TAGACGAGATTCAGTGCGGAGGGGTTATTTGCTATGATATTCGTTTTCCAGAATGGATACGCGTACATACTGCTAAAGGC
GCAAAAATAGTATTTGTAGTAGCAGAATGGCCTCTTGTTCGCCTTGAGCATTGGCGTTTATTACTGCAAGCGAGAGCAAT
CGAAAATCAATGTTATGTCGTAGCTTGTAATCGAGTAGGAAAAGATCCAAATAACGTATTTGGTGGTCACTCGCTTATTA
TTGACCCATGGGGAAAAATTGTCGCAGAGGCACAAGAAGAAGAGAGCATTCTTTATGGACAGATAGAGCTAGAAAAGATA
GAAGAGGTCCGCAGAGGAATTCCTGTTTTTATGGATCGCCGTTTAGAATTGTATAAATAA

Upstream 100 bases:

>100_bases
TACTTTCCACCTCTTTTGAAAGTTGTTACAATTCTAGTGACAAATAATATATCCTTTCCAAGATTTTGTAAAGAAAAAAA
TAAAGAACGGGGCTGAAAAA

Downstream 100 bases:

>100_bases
AAAGATTGACAAATGATTTTTATTCTTGTTATAGTCATCATCAGAAAGTTAAACATTCGAATAAGTTGCAAAACTCTTAT
CAAGAGCAGGTGGAGGGATT

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKVACIQMDIVFGEVTLNTEHAEKKIEEAMKVNPDVIVLPELWTTGYDLKRLPEISDKDGKQTKEVLSKWAKEFSVNIVG
GSVAKQTEKGVTNTMYIMDRQGNVQHEYSKVHLFQLMNEHKYLIAGHETGEFTLDEIQCGGVICYDIRFPEWIRVHTAKG
AKIVFVVAEWPLVRLEHWRLLLQARAIENQCYVVACNRVGKDPNNVFGGHSLIIDPWGKIVAEAQEEESILYGQIELEKI
EEVRRGIPVFMDRRLELYK

Sequences:

>Translated_259_residues
MKVACIQMDIVFGEVTLNTEHAEKKIEEAMKVNPDVIVLPELWTTGYDLKRLPEISDKDGKQTKEVLSKWAKEFSVNIVG
GSVAKQTEKGVTNTMYIMDRQGNVQHEYSKVHLFQLMNEHKYLIAGHETGEFTLDEIQCGGVICYDIRFPEWIRVHTAKG
AKIVFVVAEWPLVRLEHWRLLLQARAIENQCYVVACNRVGKDPNNVFGGHSLIIDPWGKIVAEAQEEESILYGQIELEKI
EEVRRGIPVFMDRRLELYK
>Mature_259_residues
MKVACIQMDIVFGEVTLNTEHAEKKIEEAMKVNPDVIVLPELWTTGYDLKRLPEISDKDGKQTKEVLSKWAKEFSVNIVG
GSVAKQTEKGVTNTMYIMDRQGNVQHEYSKVHLFQLMNEHKYLIAGHETGEFTLDEIQCGGVICYDIRFPEWIRVHTAKG
AKIVFVVAEWPLVRLEHWRLLLQARAIENQCYVVACNRVGKDPNNVFGGHSLIIDPWGKIVAEAQEEESILYGQIELEKI
EEVRRGIPVFMDRRLELYK

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=267, Percent_Identity=31.4606741573034, Blast_Score=151, Evalue=7e-37,
Organism=Homo sapiens, GI5031947, Length=258, Percent_Identity=29.0697674418605, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI297632348, Length=258, Percent_Identity=29.0697674418605, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI297632350, Length=258, Percent_Identity=29.0697674418605, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1786412, Length=255, Percent_Identity=34.1176470588235, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17556280, Length=255, Percent_Identity=31.3725490196078, Blast_Score=120, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=32.2463768115942, Blast_Score=141, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322335, Length=301, Percent_Identity=27.2425249169435, Blast_Score=104, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21355835, Length=271, Percent_Identity=33.210332103321, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17933642, Length=244, Percent_Identity=26.6393442622951, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29757; Mature: 29757

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVACIQMDIVFGEVTLNTEHAEKKIEEAMKVNPDVIVLPELWTTGYDLKRLPEISDKDG
CEEEEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCCCCC
KQTKEVLSKWAKEFSVNIVGGSVAKQTEKGVTNTMYIMDRQGNVQHEYSKVHLFQLMNEH
HHHHHHHHHHHHHEEEEEECCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
KYLIAGHETGEFTLDEIQCGGVICYDIRFPEWIRVHTAKGAKIVFVVAEWPLVRLEHWRL
EEEEEECCCCCEEEEEECCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHH
LLQARAIENQCYVVACNRVGKDPNNVFGGHSLIIDPWGKIVAEAQEEESILYGQIELEKI
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEEEHHHH
EEVRRGIPVFMDRRLELYK
HHHHCCCCEEECCEEECCC
>Mature Secondary Structure
MKVACIQMDIVFGEVTLNTEHAEKKIEEAMKVNPDVIVLPELWTTGYDLKRLPEISDKDG
CEEEEEEEEEEEEEEEECHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCCCCC
KQTKEVLSKWAKEFSVNIVGGSVAKQTEKGVTNTMYIMDRQGNVQHEYSKVHLFQLMNEH
HHHHHHHHHHHHHEEEEEECCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCC
KYLIAGHETGEFTLDEIQCGGVICYDIRFPEWIRVHTAKGAKIVFVVAEWPLVRLEHWRL
EEEEEECCCCCEEEEEECCCCEEEEECCCCCEEEEEECCCCEEEEEEECCCCHHHHHHHH
LLQARAIENQCYVVACNRVGKDPNNVFGGHSLIIDPWGKIVAEAQEEESILYGQIELEKI
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCEEEEEEEHHHH
EEVRRGIPVFMDRRLELYK
HHHHCCCCEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]