Click here to switch to the map view.

The map label for this gene is mtnA

Identifier: 152976442

GI number: 152976442

Start: 2815712

End: 2816761

Strand: Reverse

Name: mtnA

Synonym: Bcer98_2731

Alternate gene names: 152976442

Gene position: 2816761-2815712 (Counterclockwise)

Preceding gene: 152976443

Following gene: 152976441

Centisome position: 68.92

GC content: 38.29

Gene sequence:

>1050_bases
GTGAATACAACAGTTGCAGTTCCAAGAGCGATAATTTGGAAAGGTGATTCTATTACCATTTTGAATCAAACGAAGTTACC
ACATGTTGCGGAATACAAAACATTAACAAGTATTGAAGATGTTTGGAAAAGTATTGTTATGCTAGAGGTAAGAGGAGCAC
CAGCGATTGGCATTGCGGCTGCTTTTGGATTAGCTTTAGCTGCTCAAAAATATGAAGCTATAAATATAGTGGAATTCAAA
ACAAAATTCAATCGAGACTGTAATTATTTAGGGACTTCGCGCCCGACAGCAGTTAATTTATTTTGGGCTATCGACCGTAT
GAGAGCTGCAATTGAAGAGGTATCAACGATAAAGATAGCACGAGAAATATTAGAAGAGGAAGCGCTACAAATTCAACAAG
AAGATGAACAAGTGTGCCGGAGTCTTGGAGAACATGCGTTAACATGTTTCCAAGATGGCGACCGTATTTTAACAATTTGT
AATGCCGGTAGTATTGCGACTGCTCGCTATGGCACAGCATTAGCACCATTTTATATCGGAAAAGAAAAAGGAATTCATTT
ACATGCTTATGCGTGTGAAACAAGACCTGTTTTACAGGGGGCACGCTTGACCACGTGGGAGTTGAGGGAAGCTGGTGTTG
ATGTAACACTGATTACAGATAATATGGCTGCCCATACAATTCGAACAAAGAATATCTCTGCTATTATTGTGGGGGCGGAT
CGAATTGTGGCAAATGGAGATACTGCAAATAAAGTAGGAACTTTAAATTTAGCTATATTAGCAAAGCATTATCAAATTCC
TTTTTATGTCGCTGCTCCGTTGTCTACATTTGATACGAAGAAAAAAACAGGGAATGAAATCATAATCGAAGAGCGGGATG
AAACAGAAGTAACAAAAATAAACGGGCAGCAAATTGCCCCGGCTGGAATCCATATATATAATCCAGCATTTGATATAACG
CCTCATGAATTCATTTCGGGAATCATTACCGAGAAAGGAATTTTACAGGGAGATTATACAAAAGAAATTGCTTCTTTATT
TGAAAAGTAA

Upstream 100 bases:

>100_bases
ATTTGGGGAGAAGTCTATTGTTACATCAAACAAAGGGGGCAGACATTCAAGTATTCAAAACATTATTTCAACATATTGTT
TCTGAAGGAGGGATAAAGGT

Downstream 100 bases:

>100_bases
CCTTATGCAAGGGAATTTGTTATTTCTATGCCCCTATTTCTTGTACATACTTATGTATATAAGAGAAAGGGGGACAAAAA
GGTGGAAGAATGGATATCGA

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNTTVAVPRAIIWKGDSITILNQTKLPHVAEYKTLTSIEDVWKSIVMLEVRGAPAIGIAAAFGLALAAQKYEAINIVEFK
TKFNRDCNYLGTSRPTAVNLFWAIDRMRAAIEEVSTIKIAREILEEEALQIQQEDEQVCRSLGEHALTCFQDGDRILTIC
NAGSIATARYGTALAPFYIGKEKGIHLHAYACETRPVLQGARLTTWELREAGVDVTLITDNMAAHTIRTKNISAIIVGAD
RIVANGDTANKVGTLNLAILAKHYQIPFYVAAPLSTFDTKKKTGNEIIIEERDETEVTKINGQQIAPAGIHIYNPAFDIT
PHEFISGIITEKGILQGDYTKEIASLFEK

Sequences:

>Translated_349_residues
MNTTVAVPRAIIWKGDSITILNQTKLPHVAEYKTLTSIEDVWKSIVMLEVRGAPAIGIAAAFGLALAAQKYEAINIVEFK
TKFNRDCNYLGTSRPTAVNLFWAIDRMRAAIEEVSTIKIAREILEEEALQIQQEDEQVCRSLGEHALTCFQDGDRILTIC
NAGSIATARYGTALAPFYIGKEKGIHLHAYACETRPVLQGARLTTWELREAGVDVTLITDNMAAHTIRTKNISAIIVGAD
RIVANGDTANKVGTLNLAILAKHYQIPFYVAAPLSTFDTKKKTGNEIIIEERDETEVTKINGQQIAPAGIHIYNPAFDIT
PHEFISGIITEKGILQGDYTKEIASLFEK
>Mature_349_residues
MNTTVAVPRAIIWKGDSITILNQTKLPHVAEYKTLTSIEDVWKSIVMLEVRGAPAIGIAAAFGLALAAQKYEAINIVEFK
TKFNRDCNYLGTSRPTAVNLFWAIDRMRAAIEEVSTIKIAREILEEEALQIQQEDEQVCRSLGEHALTCFQDGDRILTIC
NAGSIATARYGTALAPFYIGKEKGIHLHAYACETRPVLQGARLTTWELREAGVDVTLITDNMAAHTIRTKNISAIIVGAD
RIVANGDTANKVGTLNLAILAKHYQIPFYVAAPLSTFDTKKKTGNEIIIEERDETEVTKINGQQIAPAGIHIYNPAFDIT
PHEFISGIITEKGILQGDYTKEIASLFEK

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily

Homologues:

Organism=Homo sapiens, GI72534748, Length=340, Percent_Identity=43.8235294117647, Blast_Score=248, Evalue=4e-66,
Organism=Homo sapiens, GI23943880, Length=330, Percent_Identity=41.8181818181818, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17557462, Length=332, Percent_Identity=34.9397590361446, Blast_Score=198, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI17557123, Length=161, Percent_Identity=29.8136645962733, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6325375, Length=395, Percent_Identity=35.6962025316456, Blast_Score=215, Evalue=9e-57,
Organism=Drosophila melanogaster, GI21357667, Length=369, Percent_Identity=38.7533875338753, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24651647, Length=369, Percent_Identity=38.7533875338753, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNA_BACCN (A7GS56)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001375959.1
- ProteinModelPortal:   A7GS56
- SMR:   A7GS56
- STRING:   A7GS56
- EnsemblBacteria:   EBBACT00000038752
- GeneID:   5345762
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_2731
- eggNOG:   COG0182
- GeneTree:   EBGT00050000000839
- HOGENOM:   HBG682649
- OMA:   LNQTKLP
- ProtClustDB:   PRK05720
- BioCyc:   BCER315749:BCER98_2731-MONOMER
- HAMAP:   MF_01678
- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559
- PANTHER:   PTHR10233
- TIGRFAMs:   TIGR00524
- TIGRFAMs:   TIGR00512

Pfam domain/function: PF01008 IF-2B

EC number: =5.3.1.23

Molecular weight: Translated: 38443; Mature: 38443

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: ACT_SITE 240-240 BINDING 94-94 BINDING 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTVAVPRAIIWKGDSITILNQTKLPHVAEYKTLTSIEDVWKSIVMLEVRGAPAIGIAA
CCCCEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHH
AFGLALAAQKYEAINIVEFKTKFNRDCNYLGTSRPTAVNLFWAIDRMRAAIEEVSTIKIA
HHHHHHHHHHCCEEEEEEEEHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
REILEEEALQIQQEDEQVCRSLGEHALTCFQDGDRILTICNAGSIATARYGTALAPFYIG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCEECCEEEC
KEKGIHLHAYACETRPVLQGARLTTWELREAGVDVTLITDNMAAHTIRTKNISAIIVGAD
CCCCEEEEEEEECCCHHHCCCCCEEEEHHHCCCEEEEEECCCEEEEEEECCEEEEEEECC
RIVANGDTANKVGTLNLAILAKHYQIPFYVAAPLSTFDTKKKTGNEIIIEERDETEVTKI
EEEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEE
NGQQIAPAGIHIYNPAFDITPHEFISGIITEKGILQGDYTKEIASLFEK
CCCEECCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNTTVAVPRAIIWKGDSITILNQTKLPHVAEYKTLTSIEDVWKSIVMLEVRGAPAIGIAA
CCCCEECCEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHH
AFGLALAAQKYEAINIVEFKTKFNRDCNYLGTSRPTAVNLFWAIDRMRAAIEEVSTIKIA
HHHHHHHHHHCCEEEEEEEEHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
REILEEEALQIQQEDEQVCRSLGEHALTCFQDGDRILTICNAGSIATARYGTALAPFYIG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCEECCEEEC
KEKGIHLHAYACETRPVLQGARLTTWELREAGVDVTLITDNMAAHTIRTKNISAIIVGAD
CCCCEEEEEEEECCCHHHCCCCCEEEEHHHCCCEEEEEECCCEEEEEEECCEEEEEEECC
RIVANGDTANKVGTLNLAILAKHYQIPFYVAAPLSTFDTKKKTGNEIIIEERDETEVTKI
EEEECCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEE
NGQQIAPAGIHIYNPAFDITPHEFISGIITEKGILQGDYTKEIASLFEK
CCCEECCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA