| Definition | Bacillus cereus subsp. cytotoxis NVH 391-98, complete genome. |
|---|---|
| Accession | NC_009674 |
| Length | 4,087,024 |
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The map label for this gene is fadH [H]
Identifier: 152976404
GI number: 152976404
Start: 2775308
End: 2776072
Strand: Reverse
Name: fadH [H]
Synonym: Bcer98_2692
Alternate gene names: 152976404
Gene position: 2776072-2775308 (Counterclockwise)
Preceding gene: 152976407
Following gene: 152976403
Centisome position: 67.92
GC content: 40.13
Gene sequence:
>765_bases TTGGAACGTAAAGTAGTCGTGATAACAGGTGGTTCAAGTGGAATGGGGAAAGGAATGGCAACTAAATTTGCGAAGGAAGG CACAAGAGTTGTTATTACAGGGCGTACGAAAGAAAAGCTGGACGAAACAAAAAAAGAAATTGAACAATTTGACGGACAGG TTTTAACAGTGCAAATGGATGTTCGAAACACGGAGGATATTCAGCGTATGATTGAATCCATTGATAAGGAATTTGGACGT ATCGATGTTTTGATTAATAATGCGGCAGGTAATTTTATTTGTCCGGCAGAAGATTTATCTATTAATGGATGGAATGCTGT GATTAATATTGTATTGAATGGAACGTTTTATTGTAGTCAAGCAGTAGGAAAGTATTGGATTGAAAAAGGGATAAAAGGAA ATATCATTAACATGGTAGCTACATATGCATGGGATGCTGGCCCTGGTGTAATTCATTCTGCGGCAGCGAAAGCTGGAGTG CTAGCAATGACAAAAACGTTAGCTGTAGAATGGGGGCGTAAATATGGTATTCGCGTTAATGCGATTGCTCCTGGCCCGAT TGAAAGAACAGGTGGTGCAGATAAATTATGGATTTCAGAAGAAATGGCAAAGCGTACCGTGCAGAGTGTTCCACTAGGAA GATTGGGAACACCGGAAGAAATCGCAAGCTTAGCGTTTTATTTATGCTCTGATGAGGCAGCGTACATAAATGGAACATGC ATGACAATGGATGGTGGACAACATTTACATCAGTATCCGTTTTAA
Upstream 100 bases:
>100_bases CTTGTACATAAAGATATCAGAAAAAAATAAAAATATAAAGAATTCTATCCGATAAAATGGTAAAATGAATTTGTATTCAT TTTTGGAGGAGGGGATAGGG
Downstream 100 bases:
>100_bases AGGGATGGGGACATAGATATGAACCGTGATCTATGTATCGTAAAATGTGACGAATTTGTGACATATCAGAAAAAGTATTT ACAGAAGAGCTTATATGAGG
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 254
Protein sequence:
>254_residues MERKVVVITGGSSGMGKGMATKFAKEGTRVVITGRTKEKLDETKKEIEQFDGQVLTVQMDVRNTEDIQRMIESIDKEFGR IDVLINNAAGNFICPAEDLSINGWNAVINIVLNGTFYCSQAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTVQSVPLGRLGTPEEIASLAFYLCSDEAAYINGTC MTMDGGQHLHQYPF
Sequences:
>Translated_254_residues MERKVVVITGGSSGMGKGMATKFAKEGTRVVITGRTKEKLDETKKEIEQFDGQVLTVQMDVRNTEDIQRMIESIDKEFGR IDVLINNAAGNFICPAEDLSINGWNAVINIVLNGTFYCSQAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTVQSVPLGRLGTPEEIASLAFYLCSDEAAYINGTC MTMDGGQHLHQYPF >Mature_254_residues MERKVVVITGGSSGMGKGMATKFAKEGTRVVITGRTKEKLDETKKEIEQFDGQVLTVQMDVRNTEDIQRMIESIDKEFGR IDVLINNAAGNFICPAEDLSINGWNAVINIVLNGTFYCSQAVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGV LAMTKTLAVEWGRKYGIRVNAIAPGPIERTGGADKLWISEEMAKRTVQSVPLGRLGTPEEIASLAFYLCSDEAAYINGTC MTMDGGQHLHQYPF
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI4503301, Length=224, Percent_Identity=41.5178571428571, Blast_Score=172, Evalue=2e-43, Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=34.3511450381679, Blast_Score=169, Evalue=3e-42, Organism=Homo sapiens, GI10190704, Length=248, Percent_Identity=39.9193548387097, Blast_Score=166, Evalue=1e-41, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=29.6, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=28.4046692607004, Blast_Score=109, Evalue=3e-24, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=26.5560165975104, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=29.0836653386454, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=29.7071129707113, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=29.6875, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=26.6932270916335, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=25.2032520325203, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=27.0042194092827, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI209862901, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI19923983, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI7706318, Length=188, Percent_Identity=26.5957446808511, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI40254986, Length=200, Percent_Identity=30.5, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4503817, Length=200, Percent_Identity=29.5, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI4758504, Length=258, Percent_Identity=26.3565891472868, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=26.3440860215054, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=32.9268292682927, Blast_Score=137, Evalue=7e-34, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.4110671936759, Blast_Score=129, Evalue=2e-31, Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=33.0677290836653, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=31.9391634980989, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=29.6747967479675, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI1790717, Length=243, Percent_Identity=30.0411522633745, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.8617886178862, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1789378, Length=255, Percent_Identity=29.0196078431373, Blast_Score=97, Evalue=9e-22, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=29.3650793650794, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI1787820, Length=243, Percent_Identity=30.0411522633745, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=23.5294117647059, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787526, Length=250, Percent_Identity=25.6, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=25.4901960784314, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=25.4098360655738, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1787545, Length=253, Percent_Identity=26.8774703557312, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=39.84375, Blast_Score=189, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=39.9209486166008, Blast_Score=186, Evalue=7e-48, Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=41.25, Blast_Score=177, Evalue=3e-45, Organism=Caenorhabditis elegans, GI17562904, Length=265, Percent_Identity=31.6981132075472, Blast_Score=124, Evalue=5e-29, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=33.206106870229, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI17563726, Length=263, Percent_Identity=36.1216730038023, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=29.5454545454545, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=27.6515151515151, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=31.203007518797, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17555706, Length=250, Percent_Identity=30.8, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=30, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=30, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=29.9610894941634, Blast_Score=107, Evalue=7e-24, Organism=Caenorhabditis elegans, GI17551412, Length=266, Percent_Identity=31.5789473684211, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17560220, Length=262, Percent_Identity=29.3893129770992, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=29.811320754717, Blast_Score=104, Evalue=3e-23, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=31.5589353612167, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=29.6442687747036, Blast_Score=103, Evalue=9e-23, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=28, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=30.6451612903226, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.7878787878788, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=30.0751879699248, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.7153558052434, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=26.2096774193548, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=28.1954887218045, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.7878787878788, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=25.5144032921811, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=262, Percent_Identity=27.4809160305344, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=28.7179487179487, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17558628, Length=191, Percent_Identity=32.9842931937173, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=31.0526315789474, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997099, Length=210, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17555612, Length=224, Percent_Identity=27.2321428571429, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.6, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI193203117, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI193203115, Length=188, Percent_Identity=27.1276595744681, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=35.8267716535433, Blast_Score=148, Evalue=9e-37, Organism=Saccharomyces cerevisiae, GI6322861, Length=255, Percent_Identity=30.1960784313725, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=30.8943089430894, Blast_Score=80, Evalue=3e-16, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=33.6, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=30.5882352941176, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=32.4, Blast_Score=121, Evalue=5e-28, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.4, Blast_Score=120, Evalue=1e-27, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=31.6, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=28.2258064516129, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI17737361, Length=263, Percent_Identity=28.1368821292776, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=24.5901639344262, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=27.6679841897233, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI18859837, Length=249, Percent_Identity=28.5140562248996, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357673, Length=191, Percent_Identity=30.3664921465969, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24580925, Length=194, Percent_Identity=27.8350515463918, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI116007236, Length=243, Percent_Identity=23.8683127572016, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007238, Length=183, Percent_Identity=24.5901639344262, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 27669; Mature: 27669
Theoretical pI: Translated: 6.78; Mature: 6.78
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MERKVVVITGGSSGMGKGMATKFAKEGTRVVITGRTKEKLDETKKEIEQFDGQVLTVQMD CCCEEEEEECCCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEE VRNTEDIQRMIESIDKEFGRIDVLINNAAGNFICPAEDLSINGWNAVINIVLNGTFYCSQ CCCHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCCCCHHEEEEEEECCCEEEHH AVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIRVN HHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE AIAPGPIERTGGADKLWISEEMAKRTVQSVPLGRLGTPEEIASLAFYLCSDEAAYINGTC EECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCEE MTMDGGQHLHQYPF EEECCCCCCCCCCC >Mature Secondary Structure MERKVVVITGGSSGMGKGMATKFAKEGTRVVITGRTKEKLDETKKEIEQFDGQVLTVQMD CCCEEEEEECCCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEEEEE VRNTEDIQRMIESIDKEFGRIDVLINNAAGNFICPAEDLSINGWNAVINIVLNGTFYCSQ CCCHHHHHHHHHHHHHHCCEEEEEEECCCCCEECCCCCCCCCCHHEEEEEEECCCEEEHH AVGKYWIEKGIKGNIINMVATYAWDAGPGVIHSAAAKAGVLAMTKTLAVEWGRKYGIRVN HHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE AIAPGPIERTGGADKLWISEEMAKRTVQSVPLGRLGTPEEIASLAFYLCSDEAAYINGTC EECCCCCCCCCCCCEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEECCEE MTMDGGQHLHQYPF EEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]