Click here to switch to the map view.

The map label for this gene is murB [H]

Identifier: 152976271

GI number: 152976271

Start: 2658438

End: 2659358

Strand: Reverse

Name: murB [H]

Synonym: Bcer98_2559

Alternate gene names: 152976271

Gene position: 2659358-2658438 (Counterclockwise)

Preceding gene: 152976272

Following gene: 152976270

Centisome position: 65.07

GC content: 39.2

Gene sequence:

>921_bases
ATGGGGGAGATCATTATGAAACAATTAGCAAAGGAACTCATAGAAGCAAAAGTTGGGAAAGTGTTCCTAAATGAATCATT
AGCTCGATATACAACTATGAAAATAGGTGGGCCAGCTGATATATTTGTTATTCCGACAAGCATTTCTAGTATTGAAAAGA
TTTTAGCTTTAGTGAAGAAATATAAAGTGAACTGGACGGCAATTGGACGTGGTTCCAACCTTCTTGTTTCTGATAAAGGT
ATAGAGGGTGTTGTGATTCGCTTAGGAGAAGGATTAGACCATCTTGAAGTCGAAGAAGCTACTGTAAGAGTTGGTGGAGG
ATACCCCCTTATTAAGTTGTCAACATTACTTAGCCGCCAAGGATTAGCAGGATTGGAATTTGCAAGTGGAATTCCAGGAA
GTGTTGGCGGTGCAGTATATATGAATGCTGGAGCTCATAAGTCCGATATTTCGAAAATTTTAACGAGAGCTTGCGTTATG
TTGGAAGATGGAACAGTTGCCTGGTTGTCAAAAGAAGAAATGGAATTTTCTTACCGTACTTCGGTTTTACAAACAAAGCT
TCCGGGCATTGTATTAGGAGCTGAATTTCAACTCGAACGAGGAAATCGAGAAGAAATTGTTCGCATTATGCAAAAGAATA
AAGAGTATCGCCGTGACACACAGCCGTGGAGCCACCCTTGCGCAGGAAGTATATTTAGAAATCCGCTGCCCCATTTTGCT
GGAGATTTAATCGAAAGGGCTGGACTTCGTGGATACCAAATTGGTGGTGCGAAAGTGTCTGAAGTGCATGGGAATTTTAT
TGTCAATACAGGAACAGCATCAGCTCAAGATGTTTTAGACTTAATTGGCTTTGTTAAAAGAAACATTAAAGAAAAATTTG
ATATAGATATGCATACAGAAGTAGAAATCATTGGAAGATAA

Upstream 100 bases:

>100_bases
TCCAGATGCGGCGAATAAGCTATTTGAAGTAATGAAACAACTTATGAAAAAATAACCTTAGGTGAATGTCCTGCATATTA
CTGTAATAAGGAGACTTAAT

Downstream 100 bases:

>100_bases
CTGTTATCTGTTCCGCTCGATATCATTTATGGTATAATAAGAAGATAGAACGGCATGACAAACATGCCGTTCTTTATGTT
ACATAGGGGGATCGTACATG

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase 1 [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MGEIIMKQLAKELIEAKVGKVFLNESLARYTTMKIGGPADIFVIPTSISSIEKILALVKKYKVNWTAIGRGSNLLVSDKG
IEGVVIRLGEGLDHLEVEEATVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISKILTRACVM
LEDGTVAWLSKEEMEFSYRTSVLQTKLPGIVLGAEFQLERGNREEIVRIMQKNKEYRRDTQPWSHPCAGSIFRNPLPHFA
GDLIERAGLRGYQIGGAKVSEVHGNFIVNTGTASAQDVLDLIGFVKRNIKEKFDIDMHTEVEIIGR

Sequences:

>Translated_306_residues
MGEIIMKQLAKELIEAKVGKVFLNESLARYTTMKIGGPADIFVIPTSISSIEKILALVKKYKVNWTAIGRGSNLLVSDKG
IEGVVIRLGEGLDHLEVEEATVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISKILTRACVM
LEDGTVAWLSKEEMEFSYRTSVLQTKLPGIVLGAEFQLERGNREEIVRIMQKNKEYRRDTQPWSHPCAGSIFRNPLPHFA
GDLIERAGLRGYQIGGAKVSEVHGNFIVNTGTASAQDVLDLIGFVKRNIKEKFDIDMHTEVEIIGR
>Mature_305_residues
GEIIMKQLAKELIEAKVGKVFLNESLARYTTMKIGGPADIFVIPTSISSIEKILALVKKYKVNWTAIGRGSNLLVSDKGI
EGVVIRLGEGLDHLEVEEATVRVGGGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISKILTRACVML
EDGTVAWLSKEEMEFSYRTSVLQTKLPGIVLGAEFQLERGNREEIVRIMQKNKEYRRDTQPWSHPCAGSIFRNPLPHFAG
DLIERAGLRGYQIGGAKVSEVHGNFIVNTGTASAQDVLDLIGFVKRNIKEKFDIDMHTEVEIIGR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33482; Mature: 33351

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEIIMKQLAKELIEAKVGKVFLNESLARYTTMKIGGPADIFVIPTSISSIEKILALVKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHH
YKVNWTAIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVEEATVRVGGGYPLIKLSTLLSRQ
HCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHC
GLAGLEFASGIPGSVGGAVYMNAGAHKSDISKILTRACVMLEDGTVAWLSKEEMEFSYRT
CCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHH
SVLQTKLPGIVLGAEFQLERGNREEIVRIMQKNKEYRRDTQPWSHPCAGSIFRNPLPHFA
HHHHHCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHH
GDLIERAGLRGYQIGGAKVSEVHGNFIVNTGTASAQDVLDLIGFVKRNIKEKFDIDMHTE
HHHHHHCCCCEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VEIIGR
EEEECC
>Mature Secondary Structure 
GEIIMKQLAKELIEAKVGKVFLNESLARYTTMKIGGPADIFVIPTSISSIEKILALVKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHHHHHHHHHH
YKVNWTAIGRGSNLLVSDKGIEGVVIRLGEGLDHLEVEEATVRVGGGYPLIKLSTLLSRQ
HCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEEECCCCCHHHHHHHHHHC
GLAGLEFASGIPGSVGGAVYMNAGAHKSDISKILTRACVMLEDGTVAWLSKEEMEFSYRT
CCCCCHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHH
SVLQTKLPGIVLGAEFQLERGNREEIVRIMQKNKEYRRDTQPWSHPCAGSIFRNPLPHFA
HHHHHCCCCEEEECEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHH
GDLIERAGLRGYQIGGAKVSEVHGNFIVNTGTASAQDVLDLIGFVKRNIKEKFDIDMHTE
HHHHHHCCCCEEEECCCEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
VEIIGR
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]