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The map label for this gene is fabD [H]

Identifier: 152976218

GI number: 152976218

Start: 2601901

End: 2602851

Strand: Reverse

Name: fabD [H]

Synonym: Bcer98_2504

Alternate gene names: 152976218

Gene position: 2602851-2601901 (Counterclockwise)

Preceding gene: 152976219

Following gene: 152976217

Centisome position: 63.69

GC content: 39.54

Gene sequence:

>951_bases
ATGGGAAAACTAGCATTTCTTTTTCCAGGCCAAGGTTCACAGGCAGTAGGAATGGGAAAACAGTTAGCTGAAAATAACAA
AAAAGTAGCAGAAGTATTTCAAAAAGCGGATCAAGTTTTAAATGAGCCTCTTTCACAAGTGATTTTTGAAGGGCCTCAGG
AGAAACTAACATTAACGACAAATGCACAGCCGGCATTACTCACAACGAGTTTTGCAATTTTAACAGCCTTAAATGAATAC
GATATTACCCCTGATTATGTAGCAGGACATAGTTTAGGTGAATATAGTGCGCTTGTTGCAGTTGAAGCATTAACATTTGA
AGATGCTGTTTATGCTGTGAGAAAACGTGGCGAATATATGGAAGAAGCTGTTCCGGGTGGAGAAGGCGCGATGGCAGCCA
TATTAGGTGCTGATCCGAATATGCTGAAACAAGTTACAGAAGAAGTGACAAACGAGGGGCATGCGGTGCAAATTGCCAAT
ATGAACAGTGTAAAGCAAATTGTAATTTCTGGGACAAAACAAGGGGTAGAGCTTGCTTCTCAAAAGGCAAAAGAAAAAGG
AGCGAAGCGAGCGATCCCCCTTCGAGTAAGCGGGCCGTTTCATTCTTCTCTTATGAAGCCGGCAGCTGAAAAATTTAAAA
GTGTGTTAAATGAAATTGCAATTCAAGATGCAAAGATCCCCGTTATTGCAAATGTTACAGCAGACTGTATGACAAACAGG
GAAGAGATTCAAGAAAAGCTGATTGAACAACTTTATTCACCTGTGTTATGGTACCCATCCATGGAATACATGATTGAGCA
AGGTGTAGATACATTTATTGAGATTGGACCTGGAAAAGTACTTGCTGGTCTTATGAAAGCAATTGATTCATCTGTGAAAG
TATATACAGTCTATGATGAAGAAACATTAAAAGATACCATTTCAAGTTTGAGAGGAGAAAACGGATGTTAA

Upstream 100 bases:

>100_bases
GTGCGATTCGTCAAACGAGAGAGATGGTAGCGAAAGAAGTTATTCCTACAATTTCAAGTGTAATGGAGAAAGAGCCACTC
CGATAAGAGGAGGATTTGAA

Downstream 100 bases:

>100_bases
AAGAGAAAGTAGCACTTGTTACAGGTGCATCGCGTGGAATCGGTCGTGCAATTGCAATCGATTTAGCAAAACAAGGGGCG
AAGGTAATTGTAAACTATGC

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGKLAFLFPGQGSQAVGMGKQLAENNKKVAEVFQKADQVLNEPLSQVIFEGPQEKLTLTTNAQPALLTTSFAILTALNEY
DITPDYVAGHSLGEYSALVAVEALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPNMLKQVTEEVTNEGHAVQIAN
MNSVKQIVISGTKQGVELASQKAKEKGAKRAIPLRVSGPFHSSLMKPAAEKFKSVLNEIAIQDAKIPVIANVTADCMTNR
EEIQEKLIEQLYSPVLWYPSMEYMIEQGVDTFIEIGPGKVLAGLMKAIDSSVKVYTVYDEETLKDTISSLRGENGC

Sequences:

>Translated_316_residues
MGKLAFLFPGQGSQAVGMGKQLAENNKKVAEVFQKADQVLNEPLSQVIFEGPQEKLTLTTNAQPALLTTSFAILTALNEY
DITPDYVAGHSLGEYSALVAVEALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPNMLKQVTEEVTNEGHAVQIAN
MNSVKQIVISGTKQGVELASQKAKEKGAKRAIPLRVSGPFHSSLMKPAAEKFKSVLNEIAIQDAKIPVIANVTADCMTNR
EEIQEKLIEQLYSPVLWYPSMEYMIEQGVDTFIEIGPGKVLAGLMKAIDSSVKVYTVYDEETLKDTISSLRGENGC
>Mature_315_residues
GKLAFLFPGQGSQAVGMGKQLAENNKKVAEVFQKADQVLNEPLSQVIFEGPQEKLTLTTNAQPALLTTSFAILTALNEYD
ITPDYVAGHSLGEYSALVAVEALTFEDAVYAVRKRGEYMEEAVPGGEGAMAAILGADPNMLKQVTEEVTNEGHAVQIANM
NSVKQIVISGTKQGVELASQKAKEKGAKRAIPLRVSGPFHSSLMKPAAEKFKSVLNEIAIQDAKIPVIANVTADCMTNRE
EIQEKLIEQLYSPVLWYPSMEYMIEQGVDTFIEIGPGKVLAGLMKAIDSSVKVYTVYDEETLKDTISSLRGENGC

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=312, Percent_Identity=31.4102564102564, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI27477045, Length=109, Percent_Identity=39.4495412844037, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1787334, Length=289, Percent_Identity=47.4048442906574, Blast_Score=231, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.1525423728814, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=27.3037542662116, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24665753, Length=301, Percent_Identity=35.8803986710963, Blast_Score=142, Evalue=2e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34222; Mature: 34090

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKLAFLFPGQGSQAVGMGKQLAENNKKVAEVFQKADQVLNEPLSQVIFEGPQEKLTLTT
CCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NAQPALLTTSFAILTALNEYDITPDYVAGHSLGEYSALVAVEALTFEDAVYAVRKRGEYM
CCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAVPGGEGAMAAILGADPNMLKQVTEEVTNEGHAVQIANMNSVKQIVISGTKQGVELAS
HHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCHHHHHHHH
QKAKEKGAKRAIPLRVSGPFHSSLMKPAAEKFKSVLNEIAIQDAKIPVIANVTADCMTNR
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCH
EEIQEKLIEQLYSPVLWYPSMEYMIEQGVDTFIEIGPGKVLAGLMKAIDSSVKVYTVYDE
HHHHHHHHHHHHCCEECCCCHHHHHHHCCHHHEECCCHHHHHHHHHHHCCCEEEEEEECH
ETLKDTISSLRGENGC
HHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GKLAFLFPGQGSQAVGMGKQLAENNKKVAEVFQKADQVLNEPLSQVIFEGPQEKLTLTT
CCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEC
NAQPALLTTSFAILTALNEYDITPDYVAGHSLGEYSALVAVEALTFEDAVYAVRKRGEYM
CCCCHHHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAVPGGEGAMAAILGADPNMLKQVTEEVTNEGHAVQIANMNSVKQIVISGTKQGVELAS
HHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCHHHHHHHH
QKAKEKGAKRAIPLRVSGPFHSSLMKPAAEKFKSVLNEIAIQDAKIPVIANVTADCMTNR
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHCCH
EEIQEKLIEQLYSPVLWYPSMEYMIEQGVDTFIEIGPGKVLAGLMKAIDSSVKVYTVYDE
HHHHHHHHHHHHCCEECCCCHHHHHHHCCHHHEECCCHHHHHHHHHHHCCCEEEEEEECH
ETLKDTISSLRGENGC
HHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]