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The map label for this gene is ymxG [H]

Identifier: 152976171

GI number: 152976171

Start: 2551759

End: 2552997

Strand: Reverse

Name: ymxG [H]

Synonym: Bcer98_2457

Alternate gene names: 152976171

Gene position: 2552997-2551759 (Counterclockwise)

Preceding gene: 152976172

Following gene: 152976170

Centisome position: 62.47

GC content: 34.62

Gene sequence:

>1239_bases
TTGATTAAAAAATATACTTGTAAGAATGGTGTAAGAATTGTTATGGAGAATATACCTACTGTGCGTTCAGTTGCAATTGG
GATATGGATCCATGCAGGTTCTAGAAATGAAAATGCGAAAAATAATGGGATTTCACACTTTTTGGAGCACATGTTCTTTA
AAGGTACAAAGACACGTAGTGCGAAAGAGATTGCGGAATCATTTGACAGTATCGGCGGTCAAGTAAATGCATTTACATCC
AAAGAATACACATGCTATTATACAAAAGTGCTTGATGAGCACGCAAAATATGCGCTTGATGTGTTAGCGGATATGTTTTT
TAACTCAACATTTGATGAGGCTGAATTGAAAAAAGAGAAGAAGGTTGTATTTGAAGAAATTAAAATGTACGAAGATACAC
CAGATGATATTGTACATGACATATTAACGAAAGCAACATACGAAACGCATCCACTTGGATATCCAATTTTGGGAACGGAA
GAAACGCTTGAAACATTTACAGGAGACACGTTGCGACAATACATTAAAGATCATTACACACCTGAAAATGTTGTTGTATC
AATTGCTGGAAATATTGATGAAACGTTTGTACAAACGGTAGAACAATACTTTGGTAATTATGAGGGAACAACAAATCGTG
AGCAAGTACATAGCCCAATTTTCCATTTCAATAAAGTCGCTCGCAAGAAAGAAACAGAACAAGCGCATTTATGTTTAGGA
TTTAAAGGATTACAAATGGGGCATGACGATATTTATAACTTGATTGTGCTCAATAATATTTTAGGTGGTAGCATGAGCAG
TCGCTTATTCCAAGAAGTACGGGAACAACGCGGTCTAGCATACTCTGTATTCTCATATCATTCTTCTTACGAAGATACGG
GAATGCTAACTATTTATGGTGGTACAGGAAGTCAACAATTAGATACATTGTATGACACAATACAAGAAACATTAGACACA
TTGAAAAATACAGGTATTACAGAAAAAGAACTTGTGAATAGTAAAGAGCAGCTAAAAGGGAATTTAATGTTAAGTTTAGA
GAGTACGAATAGTCGTATGAGTCGCAATGGTAAAAATGAATTGCTTCTAAGAAAACATCGCTCTCTTGATGAAATTATCG
AAAGCATTAACAACGTGACAAAACCAAATGTTGATGCATTGATTCGTGATATATTTACAAATGAATTTTCAGCAGCACTA
ATTAGTCCAAATGGTGAGTTACCAAAAAGTATGAAATAA

Upstream 100 bases:

>100_bases
ACGGATTGATTAAATACATTTGCATGACATTCATGTGCAAACTTGTTATCATTAAATAATAGCGATTATTTAGAGAAACT
GGCATTAGGAGGAAGTTTTT

Downstream 100 bases:

>100_bases
GCAAAAAAAACTGTATCTCGTGAATGCGAGATACAGTTTTTTTGTTTTCGGCAATCAAATTTCTGTTATTTTTTGTACAT
ATATAGAATAGGGTACTTAT

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENAKNNGISHFLEHMFFKGTKTRSAKEIAESFDSIGGQVNAFTS
KEYTCYYTKVLDEHAKYALDVLADMFFNSTFDEAELKKEKKVVFEEIKMYEDTPDDIVHDILTKATYETHPLGYPILGTE
ETLETFTGDTLRQYIKDHYTPENVVVSIAGNIDETFVQTVEQYFGNYEGTTNREQVHSPIFHFNKVARKKETEQAHLCLG
FKGLQMGHDDIYNLIVLNNILGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTIYGGTGSQQLDTLYDTIQETLDT
LKNTGITEKELVNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESINNVTKPNVDALIRDIFTNEFSAAL
ISPNGELPKSMK

Sequences:

>Translated_412_residues
MIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENAKNNGISHFLEHMFFKGTKTRSAKEIAESFDSIGGQVNAFTS
KEYTCYYTKVLDEHAKYALDVLADMFFNSTFDEAELKKEKKVVFEEIKMYEDTPDDIVHDILTKATYETHPLGYPILGTE
ETLETFTGDTLRQYIKDHYTPENVVVSIAGNIDETFVQTVEQYFGNYEGTTNREQVHSPIFHFNKVARKKETEQAHLCLG
FKGLQMGHDDIYNLIVLNNILGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTIYGGTGSQQLDTLYDTIQETLDT
LKNTGITEKELVNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESINNVTKPNVDALIRDIFTNEFSAAL
ISPNGELPKSMK
>Mature_412_residues
MIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENAKNNGISHFLEHMFFKGTKTRSAKEIAESFDSIGGQVNAFTS
KEYTCYYTKVLDEHAKYALDVLADMFFNSTFDEAELKKEKKVVFEEIKMYEDTPDDIVHDILTKATYETHPLGYPILGTE
ETLETFTGDTLRQYIKDHYTPENVVVSIAGNIDETFVQTVEQYFGNYEGTTNREQVHSPIFHFNKVARKKETEQAHLCLG
FKGLQMGHDDIYNLIVLNNILGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTIYGGTGSQQLDTLYDTIQETLDT
LKNTGITEKELVNSKEQLKGNLMLSLESTNSRMSRNGKNELLLRKHRSLDEIIESINNVTKPNVDALIRDIFTNEFSAAL
ISPNGELPKSMK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=420, Percent_Identity=29.5238095238095, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI46593007, Length=399, Percent_Identity=25.062656641604, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI24308013, Length=458, Percent_Identity=25.5458515283843, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI50592988, Length=432, Percent_Identity=21.0648148148148, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI155969707, Length=116, Percent_Identity=36.2068965517241, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1787770, Length=177, Percent_Identity=28.8135593220339, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=416, Percent_Identity=28.6057692307692, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17553678, Length=419, Percent_Identity=26.2529832935561, Blast_Score=169, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI17510601, Length=368, Percent_Identity=21.4673913043478, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323192, Length=394, Percent_Identity=31.4720812182741, Blast_Score=200, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6321813, Length=425, Percent_Identity=26.8235294117647, Blast_Score=145, Evalue=9e-36,
Organism=Saccharomyces cerevisiae, GI6319426, Length=402, Percent_Identity=23.8805970149254, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357875, Length=411, Percent_Identity=29.9270072992701, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646943, Length=411, Percent_Identity=29.9270072992701, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI19921772, Length=437, Percent_Identity=25.1716247139588, Blast_Score=129, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46795; Mature: 46795

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENAKNNGISHFLEHMFFKGTKTRS
CCCCEECCCCCEEHHHCCCHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCH
AKEIAESFDSIGGQVNAFTSKEYTCYYTKVLDEHAKYALDVLADMFFNSTFDEAELKKEK
HHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KVVFEEIKMYEDTPDDIVHDILTKATYETHPLGYPILGTEETLETFTGDTLRQYIKDHYT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCC
PENVVVSIAGNIDETFVQTVEQYFGNYEGTTNREQVHSPIFHFNKVARKKETEQAHLCLG
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEC
FKGLQMGHDDIYNLIVLNNILGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTIYG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCEEEEEC
GTGSQQLDTLYDTIQETLDTLKNTGITEKELVNSKEQLKGNLMLSLESTNSRMSRNGKNE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCEEEEEECCCHHHHCCCCHH
LLLRKHRSLDEIIESINNVTKPNVDALIRDIFTNEFSAALISPNGELPKSMK
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MIKKYTCKNGVRIVMENIPTVRSVAIGIWIHAGSRNENAKNNGISHFLEHMFFKGTKTRS
CCCCEECCCCCEEHHHCCCHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCH
AKEIAESFDSIGGQVNAFTSKEYTCYYTKVLDEHAKYALDVLADMFFNSTFDEAELKKEK
HHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KVVFEEIKMYEDTPDDIVHDILTKATYETHPLGYPILGTEETLETFTGDTLRQYIKDHYT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCC
PENVVVSIAGNIDETFVQTVEQYFGNYEGTTNREQVHSPIFHFNKVARKKETEQAHLCLG
CCCEEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEC
FKGLQMGHDDIYNLIVLNNILGGSMSSRLFQEVREQRGLAYSVFSYHSSYEDTGMLTIYG
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCEEEEEC
GTGSQQLDTLYDTIQETLDTLKNTGITEKELVNSKEQLKGNLMLSLESTNSRMSRNGKNE
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHCCCCEEEEEECCCHHHHCCCCHH
LLLRKHRSLDEIIESINNVTKPNVDALIRDIFTNEFSAALISPNGELPKSMK
HHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]