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The map label for this gene is asd [H]

Identifier: 152976167

GI number: 152976167

Start: 2548362

End: 2549408

Strand: Reverse

Name: asd [H]

Synonym: Bcer98_2453

Alternate gene names: 152976167

Gene position: 2549408-2548362 (Counterclockwise)

Preceding gene: 152976168

Following gene: 152976166

Centisome position: 62.38

GC content: 37.54

Gene sequence:

>1047_bases
ATGGAAAAGCAAAGAACTTTTCATGTCGCTGTAGTTGGAGCAACCGGCGCAGTTGGTGAACAAATGTTAAATACTTTAGA
GAAACGAGATTTTCCAATCGGAAAGTTAACGTTACTTTCATCGAAACGATCTGCAGGTAAGAAGCTTGTATTTAAAGGAG
AAGAATTCATAGTTCAAGAAGCAACTCCTGAAAGTTTCGAGGGAGTGGATATTGCATTATTTAGTGCTGGTGGATCCGTA
TCGAAACAACTCGCGCCAGAAGCAGCAAAACGTGGTGCGATTGTTGTTGATAATACAAGTGCATTCCGTATGGCAGAAAA
TGTGCCGCTTGTTGTACCAGAAGTAAATGAAAATGACTTAAAAGAACATAATGGTATTATTGCAAATCCAAACTGTTCTA
CAATTCAGATGGTAGTTGCTCTTGAGCCGATTCGTCAGCAGTTTGGATTAAAACGAGTAATTGTTTCCACATACCAAGCT
GTATCTGGAGCGGGTGCTGCTGCGATTCAAGAACTTCATGAACAATCACAAGCGATTTTAAATGGTGAAGAAGTAAAAGC
AAATGTTTTACCTGTATCAGGTGATAAAAAACATTTCCAAATTGCTTTTAATGCGATTCCACAAATCGACAAGTTTGAAG
ATAATGGATTTACATTTGAAGAAATGAAAATGATTAATGAAACGAAAAAAATCATGCATATGCCTGAGTTAGAAGTTGCT
GCAACATGTGTCCGTTTACCTGTTGTATCAGGTCATTCTGAGTCTGTTTATATCGAAGTAGATCAAGAAGGTGTAACAGT
AGAAGACTTGAAGAACCTACTTGCAAGTGCAGAAGGTGTAGTATTACAAGATGATCCAGCAGAACAGCTATATCCAATGC
CATCTACTGCAGTTGGTAAAAACGAAGTATTCGTTGGACGTATTCGTAAAGATTTAAATAACGAAAAAGGATTCCATCTT
TGGGTCGTATCTGATAACTTATTAAAAGGCGCCGCATGGAACTCTGTTCAAATTGCAGAACGATTAATCAAATTACAATT
AGTGTAA

Upstream 100 bases:

>100_bases
TGCAGAATATGATAAAATTAACGTTATTAAGATTAGAAGGAGATTCTGCTCCTTCTAATTCTAAGTATAGAAGGATTGGT
ATCTAGAAAGGGGCATAGTG

Downstream 100 bases:

>100_bases
ACGGCTAAGAGAAGGTGCAAAGATGAAAATTATTGTTCAAAAATTCGGTGGGACATCAGTACGTGATGAAAATGGACGTA
AGCATGCACTTCACCATATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEKQRTFHVAVVGATGAVGEQMLNTLEKRDFPIGKLTLLSSKRSAGKKLVFKGEEFIVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMAENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPIRQQFGLKRVIVSTYQA
VSGAGAAAIQELHEQSQAILNGEEVKANVLPVSGDKKHFQIAFNAIPQIDKFEDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVDQEGVTVEDLKNLLASAEGVVLQDDPAEQLYPMPSTAVGKNEVFVGRIRKDLNNEKGFHL
WVVSDNLLKGAAWNSVQIAERLIKLQLV

Sequences:

>Translated_348_residues
MEKQRTFHVAVVGATGAVGEQMLNTLEKRDFPIGKLTLLSSKRSAGKKLVFKGEEFIVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMAENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPIRQQFGLKRVIVSTYQA
VSGAGAAAIQELHEQSQAILNGEEVKANVLPVSGDKKHFQIAFNAIPQIDKFEDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVDQEGVTVEDLKNLLASAEGVVLQDDPAEQLYPMPSTAVGKNEVFVGRIRKDLNNEKGFHL
WVVSDNLLKGAAWNSVQIAERLIKLQLV
>Mature_348_residues
MEKQRTFHVAVVGATGAVGEQMLNTLEKRDFPIGKLTLLSSKRSAGKKLVFKGEEFIVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMAENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPIRQQFGLKRVIVSTYQA
VSGAGAAAIQELHEQSQAILNGEEVKANVLPVSGDKKHFQIAFNAIPQIDKFEDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVDQEGVTVEDLKNLLASAEGVVLQDDPAEQLYPMPSTAVGKNEVFVGRIRKDLNNEKGFHL
WVVSDNLLKGAAWNSVQIAERLIKLQLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=33.9130434782609, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=28.3707865168539, Blast_Score=103, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320362, Length=396, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38002; Mature: 38002

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQRTFHVAVVGATGAVGEQMLNTLEKRDFPIGKLTLLSSKRSAGKKLVFKGEEFIVQE
CCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMAENVPLVVPEVNENDL
CCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCHHEEEECCCCEEEECCCCCHH
KEHNGIIANPNCSTIQMVVALEPIRQQFGLKRVIVSTYQAVSGAGAAAIQELHEQSQAIL
HHCCCEEECCCCCEEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEEVKANVLPVSGDKKHFQIAFNAIPQIDKFEDNGFTFEEMKMINETKKIMHMPELEVA
CCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
ATCVRLPVVSGHSESVYIEVDQEGVTVEDLKNLLASAEGVVLQDDPAEQLYPMPSTAVGK
HHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCCCCCCCC
NEVFVGRIRKDLNNEKGFHLWVVSDNLLKGAAWNSVQIAERLIKLQLV
CCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MEKQRTFHVAVVGATGAVGEQMLNTLEKRDFPIGKLTLLSSKRSAGKKLVFKGEEFIVQE
CCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMAENVPLVVPEVNENDL
CCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCHHEEEECCCCEEEECCCCCHH
KEHNGIIANPNCSTIQMVVALEPIRQQFGLKRVIVSTYQAVSGAGAAAIQELHEQSQAIL
HHCCCEEECCCCCEEEEEEHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEEVKANVLPVSGDKKHFQIAFNAIPQIDKFEDNGFTFEEMKMINETKKIMHMPELEVA
CCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
ATCVRLPVVSGHSESVYIEVDQEGVTVEDLKNLLASAEGVVLQDDPAEQLYPMPSTAVGK
HHHHEEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCCCCCCCC
NEVFVGRIRKDLNNEKGFHLWVVSDNLLKGAAWNSVQIAERLIKLQLV
CCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]