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The map label for this gene is pgsA [H]

Identifier: 152976147

GI number: 152976147

Start: 2525889

End: 2526467

Strand: Reverse

Name: pgsA [H]

Synonym: Bcer98_2433

Alternate gene names: 152976147

Gene position: 2526467-2525889 (Counterclockwise)

Preceding gene: 152976148

Following gene: 152976146

Centisome position: 61.82

GC content: 33.68

Gene sequence:

>579_bases
GTGAACTTACCAAATAAAATTACGATATCTCGAATCTGCTTAATTCCAATTTTTTTGGTCATTATGATCGCGCCTTTTGA
CTGGGGTTCATATACAATTGGAAACGTAGATTTACCAATTCAACATTTAATCGGGGCGCTTATTTTTATTATTGCATCAG
CTACTGACTGGATTGATGGGCATTTAGCAAGAAAATATAATCTTGTTACAAATTTAGGGAAATTTCTGGACCCATTAGCT
GATAAATTGCTTGTTTCAGCGGCGCTTATTACATTAGTTGAAATGCAATATGTACCAGCGTGGATTGTAATTGTTATTAT
TAGTCGTGAATTTGCGGTTACAGGCTTACGACTTGTATTAGCTGGTACTGGAGAAGTTGTTGCAGCTAATATGTTAGGGA
AAATCAAGACGTGGACACAAATTATTGCAATTTCAGCCTATTTATTACATGATGTGCCGTTAAACTTAATCCATATTCCA
GTTGCTGATATTTTTATATGGATTGCATTGATTTTTACAGTTATTTCTGGATATGATTACTTTTGGAAAAATAGAGCTGT
TTTTGTCAATTCAAAATAG

Upstream 100 bases:

>100_bases
GATTAAAAACTTAGGGGGAGAACAACCTGCACAATAATAGTCATCGCTTCGATGACTTTTTTCAATGAACAAATGTTTGT
GACATGATGGAGGAATAGTT

Downstream 100 bases:

>100_bases
CAGTTTATGGGGGAATCGGAATGAATGCCGAAATTATTGCGGTTGGAACAGAATTATTATTGGGGCAAATTACAAATACA
AATGCGAAGTTTTTATCCGA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MNLPNKITISRICLIPIFLVIMIAPFDWGSYTIGNVDLPIQHLIGALIFIIASATDWIDGHLARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANMLGKIKTWTQIIAISAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGYDYFWKNRAVFVNSK

Sequences:

>Translated_192_residues
MNLPNKITISRICLIPIFLVIMIAPFDWGSYTIGNVDLPIQHLIGALIFIIASATDWIDGHLARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANMLGKIKTWTQIIAISAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGYDYFWKNRAVFVNSK
>Mature_192_residues
MNLPNKITISRICLIPIFLVIMIAPFDWGSYTIGNVDLPIQHLIGALIFIIASATDWIDGHLARKYNLVTNLGKFLDPLA
DKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVLAGTGEVVAANMLGKIKTWTQIIAISAYLLHDVPLNLIHIP
VADIFIWIALIFTVISGYDYFWKNRAVFVNSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=190, Percent_Identity=34.7368421052632, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21387; Mature: 21387

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNKITISRICLIPIFLVIMIAPFDWGSYTIGNVDLPIQHLIGALIFIIASATDWIDG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
HLARKYNLVTNLGKFLDPLADKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEE
AGTGEVVAANMLGKIKTWTQIIAISAYLLHDVPLNLIHIPVADIFIWIALIFTVISGYDY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCCHH
FWKNRAVFVNSK
HHCCCEEEEECC
>Mature Secondary Structure
MNLPNKITISRICLIPIFLVIMIAPFDWGSYTIGNVDLPIQHLIGALIFIIASATDWIDG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCHHHHH
HLARKYNLVTNLGKFLDPLADKLLVSAALITLVEMQYVPAWIVIVIISREFAVTGLRLVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEE
AGTGEVVAANMLGKIKTWTQIIAISAYLLHDVPLNLIHIPVADIFIWIALIFTVISGYDY
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHCCCHH
FWKNRAVFVNSK
HHCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]