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The map label for this gene is glcD [H]

Identifier: 152975943

GI number: 152975943

Start: 2302353

End: 2303738

Strand: Reverse

Name: glcD [H]

Synonym: Bcer98_2215

Alternate gene names: 152975943

Gene position: 2303738-2302353 (Counterclockwise)

Preceding gene: 152975944

Following gene: 152975941

Centisome position: 56.37

GC content: 39.03

Gene sequence:

>1386_bases
ATGGAAGCTACAACAGAGCACTTAGTAGTGAATTTAAAAGAAATACTTTCTGAGGAGCGAGTCGTAGTTAATATGACAGT
AAGAGAACTGCATGGTAAAGACGAATCGTATCATGCAAGTAGTTTACCTGATGTTGTGGTGTTTCCGACAACGACAGAAG
AGGTGAGTCAAATTATGAAGTTGGCAAGTCAATACGGAAAGCCTGTTGTGCCGTTTGGCGTGGGATCTAGTCTTGAAGGA
CACGTGATTCCGTATGAAAAAGGGATTACAATCGATTTCTCTTTTATGAATAAAATACTCGAAGTAAGAGAAAAGGATTT
TCTCGTAAAAGTACAACCGGGTGTAACACGCTCACAGCTTAATAAAGTATTAAAAAAATATGGTTTGTTTTTTAGCGTTG
ATCCAGGTGCAGATGCTACGTTAGGCGGGATGGCTGCAACGAATGCGAGCGGAACGACAGCGGTAAAGTACGGAGTTATG
CGAGATCAAGTGCGAGATTTAGAAGTCGTTCTTGCGGATGGAACTGTGATGCATACTGGTAATTTAGCTGTAAAGTCATC
ATCAGGTTATCATTTAAATGGTATTTTTATAGGTTCTGAGGGAACACTAGGATGTTTTACAGAATTAACGTTAAAAGTAT
ACGGTATACCGGAGCATATGGTAGCAGCAAGAGCATCATTTCCGGCGGTAAATGATGCGGTAGAAACGGTTATTCATATT
TTACAAGCTGGTATTCCTATTGCGAGAATGGAACTTGTCGATGAGCTTTCAATGAAACAGGTGAATCGATATAGTGAAAT
GAACTATAGAGAAGAACCGACATTATTTTTAGAGTTTCATGGCAATAAAGCAGGATTACATCAGGATATTGAATTTACGA
AAGAGATTGCTGGCGATCATAAATGTAAGGAATTTGTGTTTGAAGTAGAAACGGCAGCGCGCAATAAATTGTGGGATGCA
AGACATAATTTAGCTTATGCATACGTTCATAGTTATCCTGGTAAAAAACTGATGAGTACAGATGTTTGTCTTCCGGTTTC
AGAATTAGCAGATGCGATACAGTACGCAAGAGAAACATTACATACAACCGGAGTAGTTGGAGGCATTCTCGGACACGTAG
GAGATGGGAATTTTCATGTCCTTTTAATGGTGAACCCAAATGATCAAGAAGAAGTGAAAAGTGCAGAAGAAATAAATGAA
AAGATTGTTATGTACGCGCTAGAACACGGAGGAACATGTACGGGTGAGCATGGTGTAGGGATTGGGAAGCAAAAATATCA
AGAGAAAGAGCATGGACCAGCACTTCTTGTTATGCAAAAAATAAAACAGGTCCTTGATCCGCAAAATATTTTAAACCCAA
ATAAAATATTCCAAATGAAGCAGTAG

Upstream 100 bases:

>100_bases
GATGGGAAGTAAAAACTTGAATTATCTCATTTTTCGGATTATTATTTATGGAATAGTTAACTTACTTTAAAATTAAATAA
TTAATAAAGGAGAGAGGGAG

Downstream 100 bases:

>100_bases
GGGATGATTTGATGAGGGTTTTGGAGTAATGGAAATAATGGGAGAAGAATAAGAACCCCCGAGAATCGTATATGTTCTCC
GGAGGTTCTATTTTCTATGC

Product: FAD linked oxidase domain-containing protein

Products: pyruvate; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MEATTEHLVVNLKEILSEERVVVNMTVRELHGKDESYHASSLPDVVVFPTTTEEVSQIMKLASQYGKPVVPFGVGSSLEG
HVIPYEKGITIDFSFMNKILEVREKDFLVKVQPGVTRSQLNKVLKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVM
RDQVRDLEVVLADGTVMHTGNLAVKSSSGYHLNGIFIGSEGTLGCFTELTLKVYGIPEHMVAARASFPAVNDAVETVIHI
LQAGIPIARMELVDELSMKQVNRYSEMNYREEPTLFLEFHGNKAGLHQDIEFTKEIAGDHKCKEFVFEVETAARNKLWDA
RHNLAYAYVHSYPGKKLMSTDVCLPVSELADAIQYARETLHTTGVVGGILGHVGDGNFHVLLMVNPNDQEEVKSAEEINE
KIVMYALEHGGTCTGEHGVGIGKQKYQEKEHGPALLVMQKIKQVLDPQNILNPNKIFQMKQ

Sequences:

>Translated_461_residues
MEATTEHLVVNLKEILSEERVVVNMTVRELHGKDESYHASSLPDVVVFPTTTEEVSQIMKLASQYGKPVVPFGVGSSLEG
HVIPYEKGITIDFSFMNKILEVREKDFLVKVQPGVTRSQLNKVLKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVM
RDQVRDLEVVLADGTVMHTGNLAVKSSSGYHLNGIFIGSEGTLGCFTELTLKVYGIPEHMVAARASFPAVNDAVETVIHI
LQAGIPIARMELVDELSMKQVNRYSEMNYREEPTLFLEFHGNKAGLHQDIEFTKEIAGDHKCKEFVFEVETAARNKLWDA
RHNLAYAYVHSYPGKKLMSTDVCLPVSELADAIQYARETLHTTGVVGGILGHVGDGNFHVLLMVNPNDQEEVKSAEEINE
KIVMYALEHGGTCTGEHGVGIGKQKYQEKEHGPALLVMQKIKQVLDPQNILNPNKIFQMKQ
>Mature_461_residues
MEATTEHLVVNLKEILSEERVVVNMTVRELHGKDESYHASSLPDVVVFPTTTEEVSQIMKLASQYGKPVVPFGVGSSLEG
HVIPYEKGITIDFSFMNKILEVREKDFLVKVQPGVTRSQLNKVLKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVM
RDQVRDLEVVLADGTVMHTGNLAVKSSSGYHLNGIFIGSEGTLGCFTELTLKVYGIPEHMVAARASFPAVNDAVETVIHI
LQAGIPIARMELVDELSMKQVNRYSEMNYREEPTLFLEFHGNKAGLHQDIEFTKEIAGDHKCKEFVFEVETAARNKLWDA
RHNLAYAYVHSYPGKKLMSTDVCLPVSELADAIQYARETLHTTGVVGGILGHVGDGNFHVLLMVNPNDQEEVKSAEEINE
KIVMYALEHGGTCTGEHGVGIGKQKYQEKEHGPALLVMQKIKQVLDPQNILNPNKIFQMKQ

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=450, Percent_Identity=47.1111111111111, Blast_Score=445, Evalue=1e-125,
Organism=Homo sapiens, GI37595754, Length=477, Percent_Identity=44.4444444444444, Blast_Score=436, Evalue=1e-122,
Organism=Homo sapiens, GI119964728, Length=431, Percent_Identity=29.0023201856148, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI4501993, Length=219, Percent_Identity=31.0502283105023, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789351, Length=460, Percent_Identity=29.1304347826087, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787977, Length=497, Percent_Identity=26.5593561368209, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI48994907, Length=225, Percent_Identity=29.7777777777778, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71992373, Length=462, Percent_Identity=42.8571428571429, Blast_Score=388, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71992381, Length=462, Percent_Identity=41.991341991342, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71992392, Length=361, Percent_Identity=45.7063711911357, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17534361, Length=431, Percent_Identity=26.9141531322506, Blast_Score=137, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17556096, Length=459, Percent_Identity=24.400871459695, Blast_Score=106, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6320027, Length=471, Percent_Identity=36.5180467091295, Blast_Score=307, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6320764, Length=471, Percent_Identity=25.6900212314225, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320023, Length=470, Percent_Identity=26.1702127659574, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18921117, Length=431, Percent_Identity=26.4501160092807, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24639277, Length=431, Percent_Identity=26.4501160092807, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24639275, Length=431, Percent_Identity=26.4501160092807, Blast_Score=142, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24653753, Length=219, Percent_Identity=31.9634703196347, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.2.4

Molecular weight: Translated: 50886; Mature: 50886

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEATTEHLVVNLKEILSEERVVVNMTVRELHGKDESYHASSLPDVVVFPTTTEEVSQIMK
CCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHH
LASQYGKPVVPFGVGSSLEGHVIPYEKGITIDFSFMNKILEVREKDFLVKVQPGVTRSQL
HHHHHCCCEEEECCCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCEEEEECCCCCHHHH
NKVLKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVMRDQVRDLEVVLADGTVMHTG
HHHHHHHCCEEEECCCCCCCCCCEEECCCCCCHHEEHHHHHHHHCCEEEEEECCEEEEEC
NLAVKSSSGYHLNGIFIGSEGTLGCFTELTLKVYGIPEHMVAARASFPAVNDAVETVIHI
CEEEECCCCEEEEEEEECCCCCEEEHEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHH
LQAGIPIARMELVDELSMKQVNRYSEMNYREEPTLFLEFHGNKAGLHQDIEFTKEIAGDH
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCH
KCKEFVFEVETAARNKLWDARHNLAYAYVHSYPGKKLMSTDVCLPVSELADAIQYARETL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HTTGVVGGILGHVGDGNFHVLLMVNPNDQEEVKSAEEINEKIVMYALEHGGTCTGEHGVG
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHEEEEEEECCCCEECCCCCCC
IGKQKYQEKEHGPALLVMQKIKQVLDPQNILNPNKIFQMKQ
CCHHHHHHHHCCCHHHHHHHHHHHHCHHHCCCCCHHEEECC
>Mature Secondary Structure
MEATTEHLVVNLKEILSEERVVVNMTVRELHGKDESYHASSLPDVVVFPTTTEEVSQIMK
CCCCHHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHH
LASQYGKPVVPFGVGSSLEGHVIPYEKGITIDFSFMNKILEVREKDFLVKVQPGVTRSQL
HHHHHCCCEEEECCCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCEEEEECCCCCHHHH
NKVLKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVMRDQVRDLEVVLADGTVMHTG
HHHHHHHCCEEEECCCCCCCCCCEEECCCCCCHHEEHHHHHHHHCCEEEEEECCEEEEEC
NLAVKSSSGYHLNGIFIGSEGTLGCFTELTLKVYGIPEHMVAARASFPAVNDAVETVIHI
CEEEECCCCEEEEEEEECCCCCEEEHEEEEEEEECCCHHHHHHHCCCCCHHHHHHHHHHH
LQAGIPIARMELVDELSMKQVNRYSEMNYREEPTLFLEFHGNKAGLHQDIEFTKEIAGDH
HHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCH
KCKEFVFEVETAARNKLWDARHNLAYAYVHSYPGKKLMSTDVCLPVSELADAIQYARETL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
HTTGVVGGILGHVGDGNFHVLLMVNPNDQEEVKSAEEINEKIVMYALEHGGTCTGEHGVG
HHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHEEEEEEECCCCEECCCCCCC
IGKQKYQEKEHGPALLVMQKIKQVLDPQNILNPNKIFQMKQ
CCHHHHHHHHCCCHHHHHHHHHHHHCHHHCCCCCHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-lactate; ferricytochrome c

Specific reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]