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The map label for this gene is kipR [H]

Identifier: 152975807

GI number: 152975807

Start: 2165035

End: 2165802

Strand: Reverse

Name: kipR [H]

Synonym: Bcer98_2063

Alternate gene names: 152975807

Gene position: 2165802-2165035 (Counterclockwise)

Preceding gene: 152975808

Following gene: 152975806

Centisome position: 52.99

GC content: 37.37

Gene sequence:

>768_bases
ATGAGTATAAACAAAACAGCGATAAAAACCATGGATATTTTAGCATTATTTTATGAACATGAAGAGTTAACATTAACGGA
GATGGTTCAGCTTGCAGGAATGCCAAAGACAACGGTGCATCGTTTAATTGGATCGCTTGAAGAAATGGAATTTTTACAGA
AAACAGTGAGAGGAAGCTATCGGCTCGGTTTTATATTTTTACGTTTTGGACAACTTGTGTCAAAGCGATTATCTGTACGA
AATATTGCCAAACCGCATATGAAACGACTAAGGAATCGTCTTGGACAAGCTGTTAATTTAATTATTCAAGATGGCAATGA
AGCGATTTATATTGAAAAGATAGATGGAGATAAGCCTGTTCGAGTCTATACAGAAATCGGGAAACGAGCACCTTTATATG
CTGGAGCATGTCCACGCATTTTATTGTCTTATTTTTCAGAAGAAGAGCAAAAGAAATATATAGAGGAAACGAATTTAGAA
CGATTTGCAGATGGAACAATCGTTCATAAAGAGCGATTGTTAGAAGTGCTGCGTGCTGCAAAGAATAAGGGGTATACAAT
AAGCTATTCTGAATTGGAAAATCATACTGCGGCTATTGCAGCACCAATATTGGCAGCTGATGGGGAAGTAGTGGCAGGAA
TTAGTATCTCAGGATTAGCAATCGAGTATAACGAAACAACGATTCCGAAGTTTATTACAGAAATACAAGAAACCGCACAA
AATATTTCAAAAGAACTTGGCTGGAGGGAAGAGAAAGAAGGGGCATGA

Upstream 100 bases:

>100_bases
ATATTGTATAAATTGAAAGAATGTTTTATAATTTCAAATTATACGTTTATTTCGAAAGATGGGATTGTAGTTCCATTTTT
CAGAACTTAGGGGAGTTAAG

Downstream 100 bases:

>100_bases
TGAAATTTTCAGCATTGGGAGATCAAGCAGTAGTTGTGACATTTGGAGAAAGAATTCGTATAGAAGTATATAAGAAAGTG
CAAAAGTTATTTCAATTATT

Product: transcriptional regulator IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSINKTAIKTMDILALFYEHEELTLTEMVQLAGMPKTTVHRLIGSLEEMEFLQKTVRGSYRLGFIFLRFGQLVSKRLSVR
NIAKPHMKRLRNRLGQAVNLIIQDGNEAIYIEKIDGDKPVRVYTEIGKRAPLYAGACPRILLSYFSEEEQKKYIEETNLE
RFADGTIVHKERLLEVLRAAKNKGYTISYSELENHTAAIAAPILAADGEVVAGISISGLAIEYNETTIPKFITEIQETAQ
NISKELGWREEKEGA

Sequences:

>Translated_255_residues
MSINKTAIKTMDILALFYEHEELTLTEMVQLAGMPKTTVHRLIGSLEEMEFLQKTVRGSYRLGFIFLRFGQLVSKRLSVR
NIAKPHMKRLRNRLGQAVNLIIQDGNEAIYIEKIDGDKPVRVYTEIGKRAPLYAGACPRILLSYFSEEEQKKYIEETNLE
RFADGTIVHKERLLEVLRAAKNKGYTISYSELENHTAAIAAPILAADGEVVAGISISGLAIEYNETTIPKFITEIQETAQ
NISKELGWREEKEGA
>Mature_254_residues
SINKTAIKTMDILALFYEHEELTLTEMVQLAGMPKTTVHRLIGSLEEMEFLQKTVRGSYRLGFIFLRFGQLVSKRLSVRN
IAKPHMKRLRNRLGQAVNLIIQDGNEAIYIEKIDGDKPVRVYTEIGKRAPLYAGACPRILLSYFSEEEQKKYIEETNLER
FADGTIVHKERLLEVLRAAKNKGYTISYSELENHTAAIAAPILAADGEVVAGISISGLAIEYNETTIPKFITEIQETAQN
ISKELGWREEKEGA

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=250, Percent_Identity=30, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788131, Length=246, Percent_Identity=27.6422764227642, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1786715, Length=220, Percent_Identity=32.2727272727273, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788581, Length=241, Percent_Identity=25.3112033195021, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1789999, Length=228, Percent_Identity=28.5087719298246, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082359, Length=228, Percent_Identity=25.4385964912281, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790752, Length=220, Percent_Identity=26.3636363636364, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28834; Mature: 28703

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINKTAIKTMDILALFYEHEELTLTEMVQLAGMPKTTVHRLIGSLEEMEFLQKTVRGSY
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
RLGFIFLRFGQLVSKRLSVRNIAKPHMKRLRNRLGQAVNLIIQDGNEAIYIEKIDGDKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCC
RVYTEIGKRAPLYAGACPRILLSYFSEEEQKKYIEETNLERFADGTIVHKERLLEVLRAA
HHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
KNKGYTISYSELENHTAAIAAPILAADGEVVAGISISGLAIEYNETTIPKFITEIQETAQ
CCCCCEEEHHHHHCCHHHHHHHHHCCCCCEEECEEEECEEEEECCCHHHHHHHHHHHHHH
NISKELGWREEKEGA
HHHHHCCCCCCCCCC
>Mature Secondary Structure 
SINKTAIKTMDILALFYEHEELTLTEMVQLAGMPKTTVHRLIGSLEEMEFLQKTVRGSY
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
RLGFIFLRFGQLVSKRLSVRNIAKPHMKRLRNRLGQAVNLIIQDGNEAIYIEKIDGDKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCC
RVYTEIGKRAPLYAGACPRILLSYFSEEEQKKYIEETNLERFADGTIVHKERLLEVLRAA
HHHHHHCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
KNKGYTISYSELENHTAAIAAPILAADGEVVAGISISGLAIEYNETTIPKFITEIQETAQ
CCCCCEEEHHHHHCCHHHHHHHHHCCCCCEEECEEEECEEEEECCCHHHHHHHHHHHHHH
NISKELGWREEKEGA
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]