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The map label for this gene is kipI [H]

Identifier: 152975806

GI number: 152975806

Start: 2164334

End: 2165035

Strand: Reverse

Name: kipI [H]

Synonym: Bcer98_2062

Alternate gene names: 152975806

Gene position: 2165035-2164334 (Counterclockwise)

Preceding gene: 152975807

Following gene: 152975805

Centisome position: 52.97

GC content: 37.32

Gene sequence:

>702_bases
ATGAAATTTTCAGCATTGGGAGATCAAGCAGTAGTTGTGACATTTGGAGAAAGAATTCGTATAGAAGTATATAAGAAAGT
GCAAAAGTTATTTCAATTATTAAACAAAAAGCCATTTATAGGAATGATTGAGTGTGTACCATCTTTTACATCTTTAGCGG
TTTATTATGATTTGTATACAGTTTGGAAACATAATGAAAGCAATGCAATGCCATATGACTACATATGTAATTATATCCGT
GATTTGTTCTTAAGTTGTGAGAAGACGATAAGAAAAGTAGAGGATTCTATTTTCATACCTGTTTGTTACGGTGGACAATA
TGGTCCGGATTTAGAAGATGTTGCCGCATATCATAATTTGCAGGTAGAGGATGTAATCCGCATCCATAGCGAGGTAACTT
ATTTTGTTTATATGCTAGGCTTTACGCCGGGGTTCCCATATTTGGGCGGGTTACCGAGCGAGCTAGAAACACCAAGAAAA
GAAACACCATGTTTACAAATCGCACCAGGTTCGGTCGGAATCGGCGGAAGTCAAACAGGCATCTATCCATTAGAAACACC
AGGAGGTTGGCATATTATTGGCCGAACACCTATTTCTTTATTTCAGCCACATGAAAATCCGCCTACATATGTACAAAGTG
GAATGTATTTACGATTTATCCCAATAACAGAAGAAGAGTATGTAGCTTTAGAGGGAGATTAG

Upstream 100 bases:

>100_bases
ATAACGAAACAACGATTCCGAAGTTTATTACAGAAATACAAGAAACCGCACAAAATATTTCAAAAGAACTTGGCTGGAGG
GAAGAGAAAGAAGGGGCATG

Downstream 100 bases:

>100_bases
ACATGAATGTAGAGGTTTTACATGCTGGAATGTTTACAACTGTTCAAGATATAGGGAGATATCATTATCAACAATATGGT
GTTCCTGTTGGCGGTGCCAT

Product: allophanate hydrolase subunit 1

Products: NA

Alternate protein names: Sporulation inhibitor kipI [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKFSALGDQAVVVTFGERIRIEVYKKVQKLFQLLNKKPFIGMIECVPSFTSLAVYYDLYTVWKHNESNAMPYDYICNYIR
DLFLSCEKTIRKVEDSIFIPVCYGGQYGPDLEDVAAYHNLQVEDVIRIHSEVTYFVYMLGFTPGFPYLGGLPSELETPRK
ETPCLQIAPGSVGIGGSQTGIYPLETPGGWHIIGRTPISLFQPHENPPTYVQSGMYLRFIPITEEEYVALEGD

Sequences:

>Translated_233_residues
MKFSALGDQAVVVTFGERIRIEVYKKVQKLFQLLNKKPFIGMIECVPSFTSLAVYYDLYTVWKHNESNAMPYDYICNYIR
DLFLSCEKTIRKVEDSIFIPVCYGGQYGPDLEDVAAYHNLQVEDVIRIHSEVTYFVYMLGFTPGFPYLGGLPSELETPRK
ETPCLQIAPGSVGIGGSQTGIYPLETPGGWHIIGRTPISLFQPHENPPTYVQSGMYLRFIPITEEEYVALEGD
>Mature_233_residues
MKFSALGDQAVVVTFGERIRIEVYKKVQKLFQLLNKKPFIGMIECVPSFTSLAVYYDLYTVWKHNESNAMPYDYICNYIR
DLFLSCEKTIRKVEDSIFIPVCYGGQYGPDLEDVAAYHNLQVEDVIRIHSEVTYFVYMLGFTPGFPYLGGLPSELETPRK
ETPCLQIAPGSVGIGGSQTGIYPLETPGGWHIIGRTPISLFQPHENPPTYVQSGMYLRFIPITEEEYVALEGD

Specific function: Is a potent inhibitor of the autophosphorylation reaction of kinase A and its reverse reaction, but does not inhibit phosphate transfer to the Spo0F response regulator once kinase A is phosphorylated. KipI is an inhibitor of the catalytic domain of kinase

COG id: COG2049

COG function: function code E; Allophanate hydrolase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786929, Length=219, Percent_Identity=40.1826484018265, Blast_Score=154, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003833
- InterPro:   IPR020899
- InterPro:   IPR010016
- InterPro:   IPR002130 [H]

Pfam domain/function: PF02682 AHS1 [H]

EC number: NA

Molecular weight: Translated: 26419; Mature: 26419

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSALGDQAVVVTFGERIRIEVYKKVQKLFQLLNKKPFIGMIECVPSFTSLAVYYDLYT
CCCCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHHHHHE
VWKHNESNAMPYDYICNYIRDLFLSCEKTIRKVEDSIFIPVCYGGQYGPDLEDVAAYHNL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCC
QVEDVIRIHSEVTYFVYMLGFTPGFPYLGGLPSELETPRKETPCLQIAPGSVGIGGSQTG
CHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCCC
IYPLETPGGWHIIGRTPISLFQPHENPPTYVQSGMYLRFIPITEEEYVALEGD
EEEECCCCCEEEEECCCHHEECCCCCCCHHHHCCCEEEEEECCCCCEEEEECC
>Mature Secondary Structure
MKFSALGDQAVVVTFGERIRIEVYKKVQKLFQLLNKKPFIGMIECVPSFTSLAVYYDLYT
CCCCCCCCCEEEEEECCEEEHHHHHHHHHHHHHHCCCCCEEHHHHHCCHHHHHHHHHHHE
VWKHNESNAMPYDYICNYIRDLFLSCEKTIRKVEDSIFIPVCYGGQYGPDLEDVAAYHNL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHCC
QVEDVIRIHSEVTYFVYMLGFTPGFPYLGGLPSELETPRKETPCLQIAPGSVGIGGSQTG
CHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCHHHCCCCCCCCEEEECCCCCCCCCCCCC
IYPLETPGGWHIIGRTPISLFQPHENPPTYVQSGMYLRFIPITEEEYVALEGD
EEEECCCCCEEEEECCCHHEECCCCCCCHHHHCCCEEEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]