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The map label for this gene is helD [H]

Identifier: 152975742

GI number: 152975742

Start: 2089542

End: 2091884

Strand: Reverse

Name: helD [H]

Synonym: Bcer98_1990

Alternate gene names: 152975742

Gene position: 2091884-2089542 (Counterclockwise)

Preceding gene: 152975743

Following gene: 152975739

Centisome position: 51.18

GC content: 34.44

Gene sequence:

>2343_bases
ATGGAGAAAACAAAGCAAGAATGGAAGCAGGAGCAGCAGCGCGTGGATGAGGTAGTAAGCAAAGTTAGAACGCGTATAGA
TTCGTTAGAGCAGTATGTAAGTACAGTAACAAAAGATGTTGTTCAAATACGCAAACATTTTTGGGATGATGTAACAGTGA
ATGTTGATAATATAGAAGAAGCTGTAGAAACAGCGGCGAGTATAAAGCAACAAGCGGAGTTATTATCAGAACGAGAGCAA
AGCCATCGTCATATATCGAGTCAACTAAAAGGATTACAACGATTACAGCAGTCGCCATATTTTGGACGGATTGATTTTAT
AGAAGATGGTGAAGACAAGAAAGAGTCTATATATTTAGGGATTCACTCATTTTATGATGAAAGTACAGAACAGTTCCTTG
TTTATGATTGGCGGGCACCTATTTCTAGTTTGTATTATGATTATTCGTTAGGAAGAGCGAAGTATAGCGCACCTCATGAA
ACGATTTCTGGAGAGATGACTTTAAAACGTCAATATGTTATCCGTGGTGGTAAAATTCAGAATATGTTTGATACAGCAGT
TACTATTGGGGATACGATGCTGCAAGAAGTACTTGGGAATCATGCGAATACACAAATGAAAAGTATTGTATCGACTATAC
AAAAGGAACAAAATCAAATCATTCGAAATGAAACAAGTCGCTTACTTATTGTGCAAGGTGCAGCTGGAAGTGGAAAAACA
TCAGCAGCATTACAGCGCATCGCATATTTGCTATATCGTTATCGGGATACATTACATGCGAATCAGATTGTTCTTTTTTC
TCCAAATGCAATGTTCAATAGTTATATTTCTACTGTTTTGCCAGAGCTTGGGGAAGAGAATGTGAAACAAACGACGTTTC
AAAAGTATTTAGAGGATCATATCGAAAGAGAGTTTGAAGTAGAAGATCCATTTACGCAAATGGAGTATGTATTAACAAAA
ATAGAAGATGACAATTACAAGGTTCGGTTAGAAGGGATAAAGTATAAAGCTAGTTTACAATTTATTACTGCAATGGATCG
GTATATCACATTTTTAAAACAAGAAGGCATGCAATTTAAAGATATTCAGTTTAAAGGGAAAGTTATTATTTCGAAAGAGC
AAATAAAAGAGAAGTTTTATGAATTTGACTCGGCAATACGTATTCCGAATCGAATCAAACTGATCTCCGAGTGGTTATTA
AAAGAACTAAGGAAAAAAGAAAAAGTAGAAAGAAAAAAGCTGTGGGTAGAGGAAGAAATACAGTTATTAGACAAAGAAAC
ATATTTAAAAGTTCATCAACAACTGCAGAAGGAAAAGGCATATTCTGGCGGTACATTTAATGAATTTGAAAGAGAACAAA
GTATGTTAGCGGATATGGTTGTGAAAGAACATTTTATACCGCTTCGAAGACGGGTAAAGAAATTACAATTTATTCATACG
AAAGCGTTATACACACAACTATTTCAAGACCCTAACTATATAACTCAATTTTTAGATCGCGAAGAACTACCAGAGAACTG
GTGGGCAATATGCAAACAAACAGTGGAGAAAGTGAAGCATTTTTATATGCCGTATGAAGATGCAACGCCGTACTTATACA
TGAAAGATCAAATACAAGAATTGCAAAGAAATACAGCTGTAAAACATATATTTATTGATGAAGCGCAGGATTATTCGACA
TTCCAATATGCATTTTTAAAACGTATATTTCCACATACAAAAATGACAATACTTGGTGATTTTAATCAAACTATTTATGA
ACAAGCGACAAATCATTTATTTTCACAATTAAATGATTTATATGGTGAAGAGCGCAGTGAAAAAATTGTGTTGAAACGCA
GCTATCGATCTACAAAACAAATTATTGAATTTACCAAACAGTTTATTCCGCATAGCGAAGAAATTGAACCATTTGAACGA
GATGGGCGCAAGCCGGTAATGATTGAAGTGAAAGAATGGGAGAAATATGATAAGCAAATTGCAGAGGGAATAGATGATTT
AAAGAAGAGAGGGCACCGAACAATTGCGGTTATTTGTAAAACAGAAGAAGAAAGTAAAGTAGTCTATAATCGCTTTCAGC
AACTTCAAAACGTTCATCTTATAAAGAAGGAAACGAGTTCGTTTGATAGTGGTATTCTAGTGATTCCATCCTATTTATCA
AAAGGGATAGAATTCGATGCAGTTATCATTTATGATGCATCACAGTATAAACGAGAAAAGGAACGAAATTTATTTTACAC
GGTGTGTACACGTGCGATGCATGAATTAATGATTTACAATAAAGGAGAAATCAATCCGTTTTTACAATCTGTTTCACAAA
AGAAATATGAGCTTGAAAGTTAA

Upstream 100 bases:

>100_bases
TATAATTATATCAAAAATGGCGAGTGATTGTCAAACTTTTTGTTGAAATTTATATTGTACAAGATGATGAGCAGAAGAAT
GGCTGATAAGGAGTGGCGAT

Downstream 100 bases:

>100_bases
AAAAGCTGGCATAAGTCAGCTTTTTTTCGTTTGTACGCTAAGCAAAGCACCAATTGCACCGCTATAACCGTGATCTTGTA
AGAAAATGGGTCGTTTATTT

Product: UvrD/REP helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MEKTKQEWKQEQQRVDEVVSKVRTRIDSLEQYVSTVTKDVVQIRKHFWDDVTVNVDNIEEAVETAASIKQQAELLSEREQ
SHRHISSQLKGLQRLQQSPYFGRIDFIEDGEDKKESIYLGIHSFYDESTEQFLVYDWRAPISSLYYDYSLGRAKYSAPHE
TISGEMTLKRQYVIRGGKIQNMFDTAVTIGDTMLQEVLGNHANTQMKSIVSTIQKEQNQIIRNETSRLLIVQGAAGSGKT
SAALQRIAYLLYRYRDTLHANQIVLFSPNAMFNSYISTVLPELGEENVKQTTFQKYLEDHIEREFEVEDPFTQMEYVLTK
IEDDNYKVRLEGIKYKASLQFITAMDRYITFLKQEGMQFKDIQFKGKVIISKEQIKEKFYEFDSAIRIPNRIKLISEWLL
KELRKKEKVERKKLWVEEEIQLLDKETYLKVHQQLQKEKAYSGGTFNEFEREQSMLADMVVKEHFIPLRRRVKKLQFIHT
KALYTQLFQDPNYITQFLDREELPENWWAICKQTVEKVKHFYMPYEDATPYLYMKDQIQELQRNTAVKHIFIDEAQDYST
FQYAFLKRIFPHTKMTILGDFNQTIYEQATNHLFSQLNDLYGEERSEKIVLKRSYRSTKQIIEFTKQFIPHSEEIEPFER
DGRKPVMIEVKEWEKYDKQIAEGIDDLKKRGHRTIAVICKTEEESKVVYNRFQQLQNVHLIKKETSSFDSGILVIPSYLS
KGIEFDAVIIYDASQYKREKERNLFYTVCTRAMHELMIYNKGEINPFLQSVSQKKYELES

Sequences:

>Translated_780_residues
MEKTKQEWKQEQQRVDEVVSKVRTRIDSLEQYVSTVTKDVVQIRKHFWDDVTVNVDNIEEAVETAASIKQQAELLSEREQ
SHRHISSQLKGLQRLQQSPYFGRIDFIEDGEDKKESIYLGIHSFYDESTEQFLVYDWRAPISSLYYDYSLGRAKYSAPHE
TISGEMTLKRQYVIRGGKIQNMFDTAVTIGDTMLQEVLGNHANTQMKSIVSTIQKEQNQIIRNETSRLLIVQGAAGSGKT
SAALQRIAYLLYRYRDTLHANQIVLFSPNAMFNSYISTVLPELGEENVKQTTFQKYLEDHIEREFEVEDPFTQMEYVLTK
IEDDNYKVRLEGIKYKASLQFITAMDRYITFLKQEGMQFKDIQFKGKVIISKEQIKEKFYEFDSAIRIPNRIKLISEWLL
KELRKKEKVERKKLWVEEEIQLLDKETYLKVHQQLQKEKAYSGGTFNEFEREQSMLADMVVKEHFIPLRRRVKKLQFIHT
KALYTQLFQDPNYITQFLDREELPENWWAICKQTVEKVKHFYMPYEDATPYLYMKDQIQELQRNTAVKHIFIDEAQDYST
FQYAFLKRIFPHTKMTILGDFNQTIYEQATNHLFSQLNDLYGEERSEKIVLKRSYRSTKQIIEFTKQFIPHSEEIEPFER
DGRKPVMIEVKEWEKYDKQIAEGIDDLKKRGHRTIAVICKTEEESKVVYNRFQQLQNVHLIKKETSSFDSGILVIPSYLS
KGIEFDAVIIYDASQYKREKERNLFYTVCTRAMHELMIYNKGEINPFLQSVSQKKYELES
>Mature_780_residues
MEKTKQEWKQEQQRVDEVVSKVRTRIDSLEQYVSTVTKDVVQIRKHFWDDVTVNVDNIEEAVETAASIKQQAELLSEREQ
SHRHISSQLKGLQRLQQSPYFGRIDFIEDGEDKKESIYLGIHSFYDESTEQFLVYDWRAPISSLYYDYSLGRAKYSAPHE
TISGEMTLKRQYVIRGGKIQNMFDTAVTIGDTMLQEVLGNHANTQMKSIVSTIQKEQNQIIRNETSRLLIVQGAAGSGKT
SAALQRIAYLLYRYRDTLHANQIVLFSPNAMFNSYISTVLPELGEENVKQTTFQKYLEDHIEREFEVEDPFTQMEYVLTK
IEDDNYKVRLEGIKYKASLQFITAMDRYITFLKQEGMQFKDIQFKGKVIISKEQIKEKFYEFDSAIRIPNRIKLISEWLL
KELRKKEKVERKKLWVEEEIQLLDKETYLKVHQQLQKEKAYSGGTFNEFEREQSMLADMVVKEHFIPLRRRVKKLQFIHT
KALYTQLFQDPNYITQFLDREELPENWWAICKQTVEKVKHFYMPYEDATPYLYMKDQIQELQRNTAVKHIFIDEAQDYST
FQYAFLKRIFPHTKMTILGDFNQTIYEQATNHLFSQLNDLYGEERSEKIVLKRSYRSTKQIIEFTKQFIPHSEEIEPFER
DGRKPVMIEVKEWEKYDKQIAEGIDDLKKRGHRTIAVICKTEEESKVVYNRFQQLQNVHLIKKETSSFDSGILVIPSYLS
KGIEFDAVIIYDASQYKREKERNLFYTVCTRAMHELMIYNKGEINPFLQSVSQKKYELES

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 92496; Mature: 92496

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTKQEWKQEQQRVDEVVSKVRTRIDSLEQYVSTVTKDVVQIRKHFWDDVTVNVDNIEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
AVETAASIKQQAELLSEREQSHRHISSQLKGLQRLQQSPYFGRIDFIEDGEDKKESIYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEE
IHSFYDESTEQFLVYDWRAPISSLYYDYSLGRAKYSAPHETISGEMTLKRQYVIRGGKIQ
HHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHCCCCCEEHHHHHHCCCCHH
NMFDTAVTIGDTMLQEVLGNHANTQMKSIVSTIQKEQNQIIRNETSRLLIVQGAAGSGKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
SAALQRIAYLLYRYRDTLHANQIVLFSPNAMFNSYISTVLPELGEENVKQTTFQKYLEDH
HHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IEREFEVEDPFTQMEYVLTKIEDDNYKVRLEGIKYKASLQFITAMDRYITFLKQEGMQFK
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECEEEHHHHHHHHHHHHHHHHHHHCCCCEE
DIQFKGKVIISKEQIKEKFYEFDSAIRIPNRIKLISEWLLKELRKKEKVERKKLWVEEEI
CEEECCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QLLDKETYLKVHQQLQKEKAYSGGTFNEFEREQSMLADMVVKEHFIPLRRRVKKLQFIHT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALYTQLFQDPNYITQFLDREELPENWWAICKQTVEKVKHFYMPYEDATPYLYMKDQIQE
HHHHHHHHCCHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHH
LQRNTAVKHIFIDEAQDYSTFQYAFLKRIFPHTKMTILGDFNQTIYEQATNHLFSQLNDL
HHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
YGEERSEKIVLKRSYRSTKQIIEFTKQFIPHSEEIEPFERDGRKPVMIEVKEWEKYDKQI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEHHHHHHHHHHH
AEGIDDLKKRGHRTIAVICKTEEESKVVYNRFQQLQNVHLIKKETSSFDSGILVIPSYLS
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHC
KGIEFDAVIIYDASQYKREKERNLFYTVCTRAMHELMIYNKGEINPFLQSVSQKKYELES
CCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEKTKQEWKQEQQRVDEVVSKVRTRIDSLEQYVSTVTKDVVQIRKHFWDDVTVNVDNIEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
AVETAASIKQQAELLSEREQSHRHISSQLKGLQRLQQSPYFGRIDFIEDGEDKKESIYLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCEEEEE
IHSFYDESTEQFLVYDWRAPISSLYYDYSLGRAKYSAPHETISGEMTLKRQYVIRGGKIQ
HHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCHHCCCCCEEHHHHHHCCCCHH
NMFDTAVTIGDTMLQEVLGNHANTQMKSIVSTIQKEQNQIIRNETSRLLIVQGAAGSGKT
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
SAALQRIAYLLYRYRDTLHANQIVLFSPNAMFNSYISTVLPELGEENVKQTTFQKYLEDH
HHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
IEREFEVEDPFTQMEYVLTKIEDDNYKVRLEGIKYKASLQFITAMDRYITFLKQEGMQFK
HCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECEEEHHHHHHHHHHHHHHHHHHHCCCCEE
DIQFKGKVIISKEQIKEKFYEFDSAIRIPNRIKLISEWLLKELRKKEKVERKKLWVEEEI
CEEECCEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
QLLDKETYLKVHQQLQKEKAYSGGTFNEFEREQSMLADMVVKEHFIPLRRRVKKLQFIHT
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALYTQLFQDPNYITQFLDREELPENWWAICKQTVEKVKHFYMPYEDATPYLYMKDQIQE
HHHHHHHHCCHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHH
LQRNTAVKHIFIDEAQDYSTFQYAFLKRIFPHTKMTILGDFNQTIYEQATNHLFSQLNDL
HHHHHHHHEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
YGEERSEKIVLKRSYRSTKQIIEFTKQFIPHSEEIEPFERDGRKPVMIEVKEWEKYDKQI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEHHHHHHHHHHH
AEGIDDLKKRGHRTIAVICKTEEESKVVYNRFQQLQNVHLIKKETSSFDSGILVIPSYLS
HHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHC
KGIEFDAVIIYDASQYKREKERNLFYTVCTRAMHELMIYNKGEINPFLQSVSQKKYELES
CCCCCCEEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]