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The map label for this gene is yciC [H]

Identifier: 152975279

GI number: 152975279

Start: 1595170

End: 1596102

Strand: Direct

Name: yciC [H]

Synonym: Bcer98_1485

Alternate gene names: 152975279

Gene position: 1595170-1596102 (Clockwise)

Preceding gene: 152975277

Following gene: 152975280

Centisome position: 39.03

GC content: 32.26

Gene sequence:

>933_bases
ATGGTCGATGAAATGAAAAAAGTAGAAATTCATATATTAGGTGGGTTTTTAGGAAGCGGAAAATCAACATTGCTTCAAAA
CCTATTATTAGCAGAAAAGAAAAAGAATAGAAAAGTTGCTGTTTTAATGAATGAAATAGGTGAATACTCAGTAGATACAG
ATATTATTGGGAAAGAGAATGTTTTAAGGGAGCTACTAAAAGGTTGTATTTGTTGTACATTAAAAGAAGAGCTTGAAATC
CAGTTACATTCTTTATATCAACAAGAAAAGCCGGATGTCATTTACATAGAAACAACGGGAGTAGCTCACCCAATTGAAGT
ATTAGATGCATGTATCTCACCGATTTTAGCTCCTTTTCTTGAGGTGAAATCAATTATAGTCGTTTTAGATGGAGTAAGGT
GGTTAAATCGAAGTGTATTAAGTGCAAACGTTCAGCAGTTATTACAAGAACAAATAAAATATGGAAGTCATATTCTTATA
AACAAAGTAGACTTACTCACAGAAGAGGATAAGAACAAGCTTGTAGAAGAGGTACGGACTATAAATCAGCATGCTAAATT
GTATGAAACAAAGTATTGTAATATATCTTTAGCTCATATAGAAAAAGCTGAGTTTAGAAGCAAGGAAGAGCATGAGACAT
TGCATGTGAAACAGCATTTGCATATTCAAACAATGACATATCAATTTACGACACCAATCGATCAAGAAAGATTATATGAA
TGGTTATCAACATTACCTGATTGTATTTATCGTGTGAAAGGCTTTGTGAAATTTCATGGGAATAAGTATCCACACTTATT
GCAATATTCGTTTGGAGTACCAACCTTATTGGAACAAGACTTTGGCTTTCCAACTAATTTGGTTATGATAGGTGAGGGAT
TCAATCAAAATCAAATCAAAAAAGAATTAGAAATGGTAGAAAATCATGTTTAG

Upstream 100 bases:

>100_bases
TGAATGAGACAGTTTCGTTTACAAAACATACTTCTTTTAATAAAATAATGAATATAAATCGTAATTATTACGTTTTGAGA
AGATTAGAGTAGAGAAATGG

Downstream 100 bases:

>100_bases
GTGAAGAAATAGGTAGGAGTAGTTGTATGTAAAAAAAACTGAGTGGAGAGGAAGTCTCTATTGATGAAAGCTTCACTCTA
TATAAAAGCTACAAGTTATG

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVDEMKKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEI
QLHSLYQQEKPDVIYIETTGVAHPIEVLDACISPILAPFLEVKSIIVVLDGVRWLNRSVLSANVQQLLQEQIKYGSHILI
NKVDLLTEEDKNKLVEEVRTINQHAKLYETKYCNISLAHIEKAEFRSKEEHETLHVKQHLHIQTMTYQFTTPIDQERLYE
WLSTLPDCIYRVKGFVKFHGNKYPHLLQYSFGVPTLLEQDFGFPTNLVMIGEGFNQNQIKKELEMVENHV

Sequences:

>Translated_310_residues
MVDEMKKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEI
QLHSLYQQEKPDVIYIETTGVAHPIEVLDACISPILAPFLEVKSIIVVLDGVRWLNRSVLSANVQQLLQEQIKYGSHILI
NKVDLLTEEDKNKLVEEVRTINQHAKLYETKYCNISLAHIEKAEFRSKEEHETLHVKQHLHIQTMTYQFTTPIDQERLYE
WLSTLPDCIYRVKGFVKFHGNKYPHLLQYSFGVPTLLEQDFGFPTNLVMIGEGFNQNQIKKELEMVENHV
>Mature_310_residues
MVDEMKKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKENVLRELLKGCICCTLKEELEI
QLHSLYQQEKPDVIYIETTGVAHPIEVLDACISPILAPFLEVKSIIVVLDGVRWLNRSVLSANVQQLLQEQIKYGSHILI
NKVDLLTEEDKNKLVEEVRTINQHAKLYETKYCNISLAHIEKAEFRSKEEHETLHVKQHLHIQTMTYQFTTPIDQERLYE
WLSTLPDCIYRVKGFVKFHGNKYPHLLQYSFGVPTLLEQDFGFPTNLVMIGEGFNQNQIKKELEMVENHV

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=205, Percent_Identity=32.6829268292683, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI33469141, Length=205, Percent_Identity=32.6829268292683, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI148727351, Length=205, Percent_Identity=32.6829268292683, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI146231952, Length=205, Percent_Identity=32.6829268292683, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI223941779, Length=200, Percent_Identity=33, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI223941776, Length=194, Percent_Identity=32.4742268041237, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1788499, Length=165, Percent_Identity=33.9393939393939, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082430, Length=329, Percent_Identity=28.8753799392097, Blast_Score=92, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6324356, Length=231, Percent_Identity=29.004329004329, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35726; Mature: 35726

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDEMKKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKEN
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCHHH
VLRELLKGCICCTLKEELEIQLHSLYQQEKPDVIYIETTGVAHPIEVLDACISPILAPFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
EVKSIIVVLDGVRWLNRSVLSANVQQLLQEQIKYGSHILINKVDLLTEEDKNKLVEEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHH
INQHAKLYETKYCNISLAHIEKAEFRSKEEHETLHVKQHLHIQTMTYQFTTPIDQERLYE
HHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHH
WLSTLPDCIYRVKGFVKFHGNKYPHLLQYSFGVPTLLEQDFGFPTNLVMIGEGFNQNQIK
HHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCHHHHH
KELEMVENHV
HHHHHHHCCC
>Mature Secondary Structure
MVDEMKKVEIHILGGFLGSGKSTLLQNLLLAEKKKNRKVAVLMNEIGEYSVDTDIIGKEN
CCCCHHEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHCCCCCCCCCCCHHH
VLRELLKGCICCTLKEELEIQLHSLYQQEKPDVIYIETTGVAHPIEVLDACISPILAPFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
EVKSIIVVLDGVRWLNRSVLSANVQQLLQEQIKYGSHILINKVDLLTEEDKNKLVEEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCHHHHHHHHHHH
INQHAKLYETKYCNISLAHIEKAEFRSKEEHETLHVKQHLHIQTMTYQFTTPIDQERLYE
HHHHHHHHHHHCCCEEHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHH
WLSTLPDCIYRVKGFVKFHGNKYPHLLQYSFGVPTLLEQDFGFPTNLVMIGEGFNQNQIK
HHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCHHHHHCCCCCCCEEEEECCCCHHHHH
KELEMVENHV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]