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The map label for this gene is gbsB [H]

Identifier: 152975271

GI number: 152975271

Start: 1585288

End: 1586496

Strand: Direct

Name: gbsB [H]

Synonym: Bcer98_1477

Alternate gene names: 152975271

Gene position: 1585288-1586496 (Clockwise)

Preceding gene: 152975270

Following gene: 152975272

Centisome position: 38.79

GC content: 40.69

Gene sequence:

>1209_bases
ATGAGTTTAAATATGAAAGTTGAACAGATGTATAAGTTCCATCAATTTGAGGTGCCTACAGCGATTAAGCATGGAATTGG
ATCTATTCGCCATATAGGAAAAGAAGTCAAAAATTTAGGTGTATCAAAAGTATTGCTTGTCACAGATCCTGGAATTTTTA
ACGCAGGTGTTGTTGATCCTGTTATGAAATATTTAAGGGAAGAAAATGTAGAGGTAGTTATATTTCATAAGGTTGAACCG
AATCCGCCAGTACGTTTAGTTGCTGAAGGATCTGCTCTTTACAAAAAAGAAGGCTGCGATGGGCTCGTTGCAGTCGGTGG
TGGTAGTTCAATGGATACAGCAAAAGCGATTGGGGTGGAAGCAACACATGAAGGATCTATCTTAGAATATGAGGCAGCGG
AAGGGAAAAAACCACTTGAGAATCGAATTCCACCATTGACAACTATTCCAACTACAGCTGGAACAGGCTCCGAAGTAACG
CAATGGGCTGTAATTACAGATGAAGAGCGAGAATTTAAATTTAATACAGGGGGACCACTTATCGCTGCACATCTGACCAT
TATTGATCCTGAATTACATATATCTATGCCACCACATGTAACAGCTATGACAGGTGTTGATGCTTTAGCACATGCGATTG
AATGTTATACAATGAAATATGCGCAGCCTATTACAGATGCGGTTGCATTAATGGCGATTGAGTATGCATCAAAATATATT
TACCGCGCATTTGCAGACGGTGAAGATTTGGAAGCTCGTTACGGTATGGCACAAGCAGCAATGTTAGCAGGGCTATCTTA
TGGAAGTGAATCCGCAGGTGCTGCACATGCGATGAGTCAAACATTAGGCGGAATTATTCCGGTTGCCCATGGACAATGTG
TTGCAGCTATGATGGGTCCAGTTATGGAATTTAACTGGAAAGGAAATCCTGAAAAGTTTGCACGTATTGCGCAAGCGGTA
GGAATTAATACGCATGAATTATCGACTGAAGATGCAGCGAAAGCGGCAGTAAATTGGATGTATGATCTCGTAGAAAATCT
AGAAATACCTACACTTGAAAAACAAGGTGTACCAGCTGATATGATTGAGCGCCTAGCCAAAGAAGCGATGAAAGACCCTC
AAACGGTTGGGAACCCGCGTGACTTAACAGTAAAAGATTATGAATGGATATACAAAAGATGTTTTAATCTAGTTCCAAAA
ACTGTATAG

Upstream 100 bases:

>100_bases
AAGAATATACTGAAATCAAACATATTTATCGAAATACGAAACCGGAAGCAATTAACTGGTTTAAATAAAGGAATGAAGAA
AAAACAGGGGGTTGTCATGT

Downstream 100 bases:

>100_bases
AGGAAAAGAAACATAAAAGGATCTGCTTCTTATGAATGCAGGTCCTTTTGTTATAAGAGAAAATCTGTATTCATTATATG
AAATGAAAAGGAATTTTTCT

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSLNMKVEQMYKFHQFEVPTAIKHGIGSIRHIGKEVKNLGVSKVLLVTDPGIFNAGVVDPVMKYLREENVEVVIFHKVEP
NPPVRLVAEGSALYKKEGCDGLVAVGGGSSMDTAKAIGVEATHEGSILEYEAAEGKKPLENRIPPLTTIPTTAGTGSEVT
QWAVITDEEREFKFNTGGPLIAAHLTIIDPELHISMPPHVTAMTGVDALAHAIECYTMKYAQPITDAVALMAIEYASKYI
YRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEFNWKGNPEKFARIAQAV
GINTHELSTEDAAKAAVNWMYDLVENLEIPTLEKQGVPADMIERLAKEAMKDPQTVGNPRDLTVKDYEWIYKRCFNLVPK
TV

Sequences:

>Translated_402_residues
MSLNMKVEQMYKFHQFEVPTAIKHGIGSIRHIGKEVKNLGVSKVLLVTDPGIFNAGVVDPVMKYLREENVEVVIFHKVEP
NPPVRLVAEGSALYKKEGCDGLVAVGGGSSMDTAKAIGVEATHEGSILEYEAAEGKKPLENRIPPLTTIPTTAGTGSEVT
QWAVITDEEREFKFNTGGPLIAAHLTIIDPELHISMPPHVTAMTGVDALAHAIECYTMKYAQPITDAVALMAIEYASKYI
YRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEFNWKGNPEKFARIAQAV
GINTHELSTEDAAKAAVNWMYDLVENLEIPTLEKQGVPADMIERLAKEAMKDPQTVGNPRDLTVKDYEWIYKRCFNLVPK
TV
>Mature_401_residues
SLNMKVEQMYKFHQFEVPTAIKHGIGSIRHIGKEVKNLGVSKVLLVTDPGIFNAGVVDPVMKYLREENVEVVIFHKVEPN
PPVRLVAEGSALYKKEGCDGLVAVGGGSSMDTAKAIGVEATHEGSILEYEAAEGKKPLENRIPPLTTIPTTAGTGSEVTQ
WAVITDEEREFKFNTGGPLIAAHLTIIDPELHISMPPHVTAMTGVDALAHAIECYTMKYAQPITDAVALMAIEYASKYIY
RAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEFNWKGNPEKFARIAQAVG
INTHELSTEDAAKAAVNWMYDLVENLEIPTLEKQGVPADMIERLAKEAMKDPQTVGNPRDLTVKDYEWIYKRCFNLVPKT
V

Specific function: Essential for the utilization of choline as a precursor [H]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=403, Percent_Identity=29.5285359801489, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI48994951, Length=379, Percent_Identity=35.3562005277045, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI1789163, Length=372, Percent_Identity=35.4838709677419, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87082107, Length=384, Percent_Identity=31.7708333333333, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1787493, Length=394, Percent_Identity=29.4416243654822, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1789386, Length=398, Percent_Identity=25.6281407035176, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=396, Percent_Identity=28.030303030303, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6321181, Length=393, Percent_Identity=33.3333333333333, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24657991, Length=425, Percent_Identity=24.9411764705882, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 43659; Mature: 43527

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNMKVEQMYKFHQFEVPTAIKHGIGSIRHIGKEVKNLGVSKVLLVTDPGIFNAGVVDP
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
VMKYLREENVEVVIFHKVEPNPPVRLVAEGSALYKKEGCDGLVAVGGGSSMDTAKAIGVE
HHHHHHHCCCEEEEEEECCCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHCCC
ATHEGSILEYEAAEGKKPLENRIPPLTTIPTTAGTGSEVTQWAVITDEEREFKFNTGGPL
CCCCCCEEEEECCCCCCCHHHCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEECCCCCE
IAAHLTIIDPELHISMPPHVTAMTGVDALAHAIECYTMKYAQPITDAVALMAIEYASKYI
EEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGP
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEECCCCCHHHHHHCC
VMEFNWKGNPEKFARIAQAVGINTHELSTEDAAKAAVNWMYDLVENLEIPTLEKQGVPAD
CEEECCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
MIERLAKEAMKDPQTVGNPRDLTVKDYEWIYKRCFNLVPKTV
HHHHHHHHHHCCCHHCCCCCCCEEHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SLNMKVEQMYKFHQFEVPTAIKHGIGSIRHIGKEVKNLGVSKVLLVTDPGIFNAGVVDP
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHH
VMKYLREENVEVVIFHKVEPNPPVRLVAEGSALYKKEGCDGLVAVGGGSSMDTAKAIGVE
HHHHHHHCCCEEEEEEECCCCCCEEEEECCCHHHHHCCCCEEEEECCCCCCCHHHHHCCC
ATHEGSILEYEAAEGKKPLENRIPPLTTIPTTAGTGSEVTQWAVITDEEREFKFNTGGPL
CCCCCCEEEEECCCCCCCHHHCCCCCEECCCCCCCCCCCEEEEEEECCCCCEEECCCCCE
IAAHLTIIDPELHISMPPHVTAMTGVDALAHAIECYTMKYAQPITDAVALMAIEYASKYI
EEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGP
HHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEECCCCCHHHHHHCC
VMEFNWKGNPEKFARIAQAVGINTHELSTEDAAKAAVNWMYDLVENLEIPTLEKQGVPAD
CEEECCCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
MIERLAKEAMKDPQTVGNPRDLTVKDYEWIYKRCFNLVPKTV
HHHHHHHHHHCCCHHCCCCCCCEEHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8752328; 9384377 [H]