Click here to switch to the map view.

The map label for this gene is yhxA [H]

Identifier: 152975130

GI number: 152975130

Start: 1434107

End: 1435462

Strand: Direct

Name: yhxA [H]

Synonym: Bcer98_1331

Alternate gene names: 152975130

Gene position: 1434107-1435462 (Clockwise)

Preceding gene: 152975129

Following gene: 152975132

Centisome position: 35.09

GC content: 40.12

Gene sequence:

>1356_bases
ATGGTGAAAATGAAGCAAACAGATGCACTACTTGTAAAGGATGAAAAATATGTTTGGCACGGCATGCGACCATTTAGCCC
GAAAGGAATAATGGTTGGAGCGAAAGCAGAAGGGTGCTGGGTAGAAGATATAGACGGGAAAAGATATTTAGATGGAATGA
GTGGTCTTTGGTGTGTAAATAGCGGATATGGGCGAAAAGAGCTTGCTGAGGCGGCGTATGAGCAATTGCAAAGGTTATCC
TATTTTCCAATGTCACAATCGCATGAGCCTGCAATAAAACTTGCCGAAAAATTAAATGAATGGTTAGGAGGAGAATATGT
TATTTTCTTCTCTAATAGTGGTTCGGAAGCAAACGAAACAGCATTTAAAATAGCAAGGCAATATTATGCCCAAAAAGGGG
AAGCATCCCGCTATAAATTTATATCGCGTTATCGCGGTTACCACGGAAATACGATGGCAACGATGGCAGCGACCGGACAG
GCGCAGCGTAAATATCAATATGAGCCATTTGCTTCAGGCTTTTTACATGTAACACCACCAGATTGTTATCGAATGCCGGA
AATAAAATCGCAAGACATTTATGATGTAGAGTGTGTAAAAGAAATCGATCGCGTTATGACATGGGAATTAGGCGGAACGA
TCGCTGGGTTTATTATGGAGCCAATCATTACAGGTGGTGGCATTTTAATGCCGCCACAATCCTATATGAAGGCTGTGCAT
GAAATTTGTCAAAAACATGGAGCTTTACTGATTAGTGATGAAGTTATTTGTGGTTTTGGTCGGACTGGAAAAGCATTTGG
CTTTATGAATTATGGTGTGAAACCTGATATTGTGACAATGGCAAAAGGGATAACAAGTGCATATTTACCATTGTCGGCGA
CAGCGGTAAAAAAAGAAATATATGAAGCATTTAAAGGGACAGGGGAATATGAGTTTTTCCGTCATATTAATACATTTGGT
GGAAACCCCGCAGCTTGTGCACTTGCACTTAAAAACTTAGAAATTATGGAAAATGAAAATTTAATTGAGCGTTCTGCACA
AATGGGAGCTCTCTTGTTAGAACAGTTAAAAGAAGAACTTGAAGAGCACCCTTTCGTCGGAGATATTCGAGGAAAAGGAT
TGCTTGTTGGGATTGAGTTAGTTCGTAATAAACAGACGAAAGAACCGATTGAGGATGAGAAAATAGCAAGCGTAGTGAAT
GGTTGTAAAGAAAAGGGATTAATCATTGGACGAAATGGGATGACAACAGCGGGCTACAACAATGTGTTAACGTTGGCACC
ACCGCTTATTATTTCAAGTGAGGAAATTGCTTTTGTAGTAGGGACGCTGAAAACAGCGATGGATTGTATAAAATAG

Upstream 100 bases:

>100_bases
TTGTATCGTTCATGTGGAATGAAGATAAGCAGGAAGTTTTAACTCATCATGGCACCAGCACAGCTTGAGAAAGAATAAGT
TGTTATGAAAGGTGGAATGT

Downstream 100 bases:

>100_bases
GAAACAGCAAGCCATATTGTTTGGCTTGCTGTTTTATGATGAAGATTATGCACTTTGCTTTAACTGCTTATCTTTCACAC
CGAAAGAGTACTTCAGCATT

Product: aminotransferase

Products: S-adenosyl-4-methylthio-2-oxobutanoate; 7,8-diaminononanoate

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MVKMKQTDALLVKDEKYVWHGMRPFSPKGIMVGAKAEGCWVEDIDGKRYLDGMSGLWCVNSGYGRKELAEAAYEQLQRLS
YFPMSQSHEPAIKLAEKLNEWLGGEYVIFFSNSGSEANETAFKIARQYYAQKGEASRYKFISRYRGYHGNTMATMAATGQ
AQRKYQYEPFASGFLHVTPPDCYRMPEIKSQDIYDVECVKEIDRVMTWELGGTIAGFIMEPIITGGGILMPPQSYMKAVH
EICQKHGALLISDEVICGFGRTGKAFGFMNYGVKPDIVTMAKGITSAYLPLSATAVKKEIYEAFKGTGEYEFFRHINTFG
GNPAACALALKNLEIMENENLIERSAQMGALLLEQLKEELEEHPFVGDIRGKGLLVGIELVRNKQTKEPIEDEKIASVVN
GCKEKGLIIGRNGMTTAGYNNVLTLAPPLIISSEEIAFVVGTLKTAMDCIK

Sequences:

>Translated_451_residues
MVKMKQTDALLVKDEKYVWHGMRPFSPKGIMVGAKAEGCWVEDIDGKRYLDGMSGLWCVNSGYGRKELAEAAYEQLQRLS
YFPMSQSHEPAIKLAEKLNEWLGGEYVIFFSNSGSEANETAFKIARQYYAQKGEASRYKFISRYRGYHGNTMATMAATGQ
AQRKYQYEPFASGFLHVTPPDCYRMPEIKSQDIYDVECVKEIDRVMTWELGGTIAGFIMEPIITGGGILMPPQSYMKAVH
EICQKHGALLISDEVICGFGRTGKAFGFMNYGVKPDIVTMAKGITSAYLPLSATAVKKEIYEAFKGTGEYEFFRHINTFG
GNPAACALALKNLEIMENENLIERSAQMGALLLEQLKEELEEHPFVGDIRGKGLLVGIELVRNKQTKEPIEDEKIASVVN
GCKEKGLIIGRNGMTTAGYNNVLTLAPPLIISSEEIAFVVGTLKTAMDCIK
>Mature_451_residues
MVKMKQTDALLVKDEKYVWHGMRPFSPKGIMVGAKAEGCWVEDIDGKRYLDGMSGLWCVNSGYGRKELAEAAYEQLQRLS
YFPMSQSHEPAIKLAEKLNEWLGGEYVIFFSNSGSEANETAFKIARQYYAQKGEASRYKFISRYRGYHGNTMATMAATGQ
AQRKYQYEPFASGFLHVTPPDCYRMPEIKSQDIYDVECVKEIDRVMTWELGGTIAGFIMEPIITGGGILMPPQSYMKAVH
EICQKHGALLISDEVICGFGRTGKAFGFMNYGVKPDIVTMAKGITSAYLPLSATAVKKEIYEAFKGTGEYEFFRHINTFG
GNPAACALALKNLEIMENENLIERSAQMGALLLEQLKEELEEHPFVGDIRGKGLLVGIELVRNKQTKEPIEDEKIASVVN
GCKEKGLIIGRNGMTTAGYNNVLTLAPPLIISSEEIAFVVGTLKTAMDCIK

Specific function: Essential for glycerol catabolism [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=428, Percent_Identity=33.1775700934579, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI24119277, Length=449, Percent_Identity=30.5122494432071, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI37574042, Length=421, Percent_Identity=34.2042755344418, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI226442705, Length=419, Percent_Identity=34.3675417661098, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=34.7715736040609, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI4557809, Length=434, Percent_Identity=26.7281105990783, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI284507298, Length=329, Percent_Identity=29.483282674772, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI188536080, Length=414, Percent_Identity=24.6376811594203, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679950, Length=414, Percent_Identity=24.6376811594203, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38679946, Length=414, Percent_Identity=24.6376811594203, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI1789016, Length=439, Percent_Identity=30.2961275626424, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI145693181, Length=411, Percent_Identity=29.1970802919708, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=29.8029556650246, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787560, Length=433, Percent_Identity=30.9468822170901, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1786991, Length=442, Percent_Identity=30.9954751131222, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=29.4258373205742, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=26.2839879154079, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=458, Percent_Identity=32.7510917030568, Blast_Score=207, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI71992977, Length=449, Percent_Identity=31.6258351893096, Blast_Score=187, Evalue=9e-48,
Organism=Caenorhabditis elegans, GI25144271, Length=426, Percent_Identity=28.8732394366197, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=424, Percent_Identity=26.1792452830189, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=411, Percent_Identity=23.1143552311436, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323470, Length=446, Percent_Identity=30.0448430493274, Blast_Score=180, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6324386, Length=470, Percent_Identity=26.8085106382979, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=31.615925058548, Blast_Score=215, Evalue=6e-56,
Organism=Drosophila melanogaster, GI28574759, Length=428, Percent_Identity=31.3084112149533, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=32.5526932084309, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21357415, Length=435, Percent_Identity=27.3563218390805, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI281366494, Length=406, Percent_Identity=23.1527093596059, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667139, Length=406, Percent_Identity=23.1527093596059, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24667143, Length=406, Percent_Identity=23.1527093596059, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.62

Molecular weight: Translated: 50138; Mature: 50138

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKMKQTDALLVKDEKYVWHGMRPFSPKGIMVGAKAEGCWVEDIDGKRYLDGMSGLWCVN
CCCCCCCCEEEEECCCCEECCCCCCCCCCEEEECCCCCCEEECCCCCHHHCCCCCEEEEC
SGYGRKELAEAAYEQLQRLSYFPMSQSHEPAIKLAEKLNEWLGGEYVIFFSNSGSEANET
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
AFKIARQYYAQKGEASRYKFISRYRGYHGNTMATMAATGQAQRKYQYEPFASGFLHVTPP
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCCCCCCCCEEECCCC
DCYRMPEIKSQDIYDVECVKEIDRVMTWELGGTIAGFIMEPIITGGGILMPPQSYMKAVH
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHH
EICQKHGALLISDEVICGFGRTGKAFGFMNYGVKPDIVTMAKGITSAYLPLSATAVKKEI
HHHHHCCCEEEECCEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
YEAFKGTGEYEFFRHINTFGGNPAACALALKNLEIMENENLIERSAQMGALLLEQLKEEL
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EEHPFVGDIRGKGLLVGIELVRNKQTKEPIEDEKIASVVNGCKEKGLIIGRNGMTTAGYN
HHCCCEECCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCC
NVLTLAPPLIISSEEIAFVVGTLKTAMDCIK
CEEEECCCEEECCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MVKMKQTDALLVKDEKYVWHGMRPFSPKGIMVGAKAEGCWVEDIDGKRYLDGMSGLWCVN
CCCCCCCCEEEEECCCCEECCCCCCCCCCEEEECCCCCCEEECCCCCHHHCCCCCEEEEC
SGYGRKELAEAAYEQLQRLSYFPMSQSHEPAIKLAEKLNEWLGGEYVIFFSNSGSEANET
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
AFKIARQYYAQKGEASRYKFISRYRGYHGNTMATMAATGQAQRKYQYEPFASGFLHVTPP
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCCCCCCCCEEECCCC
DCYRMPEIKSQDIYDVECVKEIDRVMTWELGGTIAGFIMEPIITGGGILMPPQSYMKAVH
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHH
EICQKHGALLISDEVICGFGRTGKAFGFMNYGVKPDIVTMAKGITSAYLPLSATAVKKEI
HHHHHCCCEEEECCEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHH
YEAFKGTGEYEFFRHINTFGGNPAACALALKNLEIMENENLIERSAQMGALLLEQLKEEL
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EEHPFVGDIRGKGLLVGIELVRNKQTKEPIEDEKIASVVNGCKEKGLIIGRNGMTTAGYN
HHCCCEECCCCCEEEEEHHHHHCCCCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCC
NVLTLAPPLIISSEEIAFVVGTLKTAMDCIK
CEEEECCCEEECCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; 8-amino-7-oxononanoate

Specific reaction: S-adenosyl-L-methionine + 8-amino-7-oxononanoate = S-adenosyl-4-methylthio-2-oxobutanoate + 7,8-diaminononanoate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 8969498; 8436953 [H]