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The map label for this gene is ywcA [H]

Identifier: 152975129

GI number: 152975129

Start: 1432394

End: 1433944

Strand: Direct

Name: ywcA [H]

Synonym: Bcer98_1330

Alternate gene names: 152975129

Gene position: 1432394-1433944 (Clockwise)

Preceding gene: 152975128

Following gene: 152975130

Centisome position: 35.05

GC content: 39.97

Gene sequence:

>1551_bases
GTGAATACGACGGCATTTATACTGTTTTTAATAATTGTGCTTGGTACGCTAGTGATCACGTATTTTGCCTCGAAAAAAAC
GAAAAATGCGAGCGAGTTTTATACAGCTGGCGGAGGATTAACGGGTTGGCAAAATGGACTGGCTATTGCTGGTGATTATA
TGTCAGCTGCCTCGTTTCTTGGAATTGCAGGAGCGATTGCGTTAACGGGATTTGATGGCTTTTTTTACAGCATTGGTTTT
CTAGTTGCTTATTTAGTCGTGTTATATTTAGTAGCTGAGCCCTTGCGGAATTTAGGGAAATATACACTAGCGGATATGAT
TGCAGCACGTTTTAATGCGAAAAAAGTGCGAGGCATTGCGGCGTTAAATACAATGACCATCTCCATTTTTTATATGATTG
CTCAATTGGTAGGAGCGGGTGCACTTATTAAATTATTGTTAGGGATTGAATATACAACGTCAGTTTTAATCGTTGGTACA
TTAATGACGGTATATGTTATTTTTGGGGGCATGACGGCAACGAGCTGGGTACAAATTGTAAAAGCGGTATTACTTATGGC
AGGTACATTTATTATTTCAGTCATTGTATTTGCCAAATTTCATTTTAGTATAACGGACATGTTCACCCAGATGAAAACAG
CAACACCGCTGAAAGAAGCATTCTTACATCCAGGAGTGAAATATAAAGATGGACTGGATACACTTTCTTTAAATTTAGGA
CTTGTTCTTGGAACAGCAGGCTTACCTCATATTCTTGTGCGCTTTTTTACGGTTCGCGATGCAAAAACAGCACGTCAATC
TGTTGTATGCGCAACATGGTTAATCGGTGCATTTTATATTATGACGATTTTTCTCGGCTTTGGTGCAGCTGCATTTGTTG
GAAATGCAGCGATTGTGAAGGCGAACCCAGCAGGGAATATGGCAGCGCCGCTATTAGCCAAAGCGCTGGGAGGAGATTTC
TTATTTGCCTTTGTTTCTGCTATTGCATTTGCAACGATTTTAGCCGTTGTAGCGGGACTTGTTTTAACAGCTGCTTCAGC
TTTTGCTCACGATTTTTATAATGAAATTATTCGCAAGGGGAAAGCGACCGAGAAAGAACAAGTATCGATGGCGCGCTATG
CATCACTTGGCGTAGCTATATTGTCGATTATTTTGGAGCTATTTGCTCAAACGCTCAATGTTGCGTTCTTAGTTTCCTTA
GCATTTGCAGTTGCTGCAAGTGCGAATTTACCCGTTATTTTATATACAATTTATTGGAAGCGTTTTAATACGACGGGGGC
TATTTGTGGAATGCTTGTTGGATTAATTTCAGCCATTGTTTTAGTAGCATTTAGTCCAAATGTGTGGAGCCCAGAAGCCG
GGAAAGCAATTTTTATTGGCGAGGCGTTATTCCCTTATACAACACCAGGAATTATTTCCATTCCACTCGGATTTTTGGCG
GCTTACTTAGGAACAATTTTTTCCAGCAGGAAAGAGGATAAAGCGAAATTTGATGAAATTCTTGTTAAATCTAATACAGG
ATATGGCGTGAGTGATGTTTCTAGTCATTAA

Upstream 100 bases:

>100_bases
TGACGTGGGCGCTTTGTATGATTTATAGCAAAAAAGCTGAATCATTTGATGAAATTGCTCAGAGGATTCTCCACGATGTG
AAAAAAGGGAGGGGATAAAA

Downstream 100 bases:

>100_bases
ACGAAAGAGCTTTCCGATTTGGGAGAGCTCTTTTTCATTTTAAACGCTGGAATGGGTAGGATTTGTATCGTTCATGTGGA
ATGAAGATAAGCAGGAAGTT

Product: SSS family solute/sodium (Na+) symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNTTAFILFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFNAKKVRGIAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFHFSITDMFTQMKTATPLKEAFLHPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVCATWLIGAFYIMTIFLGFGAAAFVGNAAIVKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKATEKEQVSMARYASLGVAILSIILELFAQTLNVAFLVSL
AFAVAASANLPVILYTIYWKRFNTTGAICGMLVGLISAIVLVAFSPNVWSPEAGKAIFIGEALFPYTTPGIISIPLGFLA
AYLGTIFSSRKEDKAKFDEILVKSNTGYGVSDVSSH

Sequences:

>Translated_516_residues
MNTTAFILFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFNAKKVRGIAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFHFSITDMFTQMKTATPLKEAFLHPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVCATWLIGAFYIMTIFLGFGAAAFVGNAAIVKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKATEKEQVSMARYASLGVAILSIILELFAQTLNVAFLVSL
AFAVAASANLPVILYTIYWKRFNTTGAICGMLVGLISAIVLVAFSPNVWSPEAGKAIFIGEALFPYTTPGIISIPLGFLA
AYLGTIFSSRKEDKAKFDEILVKSNTGYGVSDVSSH
>Mature_516_residues
MNTTAFILFLIIVLGTLVITYFASKKTKNASEFYTAGGGLTGWQNGLAIAGDYMSAASFLGIAGAIALTGFDGFFYSIGF
LVAYLVVLYLVAEPLRNLGKYTLADMIAARFNAKKVRGIAALNTMTISIFYMIAQLVGAGALIKLLLGIEYTTSVLIVGT
LMTVYVIFGGMTATSWVQIVKAVLLMAGTFIISVIVFAKFHFSITDMFTQMKTATPLKEAFLHPGVKYKDGLDTLSLNLG
LVLGTAGLPHILVRFFTVRDAKTARQSVVCATWLIGAFYIMTIFLGFGAAAFVGNAAIVKANPAGNMAAPLLAKALGGDF
LFAFVSAIAFATILAVVAGLVLTAASAFAHDFYNEIIRKGKATEKEQVSMARYASLGVAILSIILELFAQTLNVAFLVSL
AFAVAASANLPVILYTIYWKRFNTTGAICGMLVGLISAIVLVAFSPNVWSPEAGKAIFIGEALFPYTTPGIISIPLGFLA
AYLGTIFSSRKEDKAKFDEILVKSNTGYGVSDVSSH

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI310128183, Length=456, Percent_Identity=25.8771929824561, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1790503, Length=529, Percent_Identity=45.9357277882798, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1787251, Length=457, Percent_Identity=27.1334792122538, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87082237, Length=448, Percent_Identity=22.7678571428571, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 54875; Mature: 54875

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00456 NA_SOLUT_SYMP_1 ; PS00457 NA_SOLUT_SYMP_2 ; PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]