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The map label for this gene is aspB [H]

Identifier: 152975068

GI number: 152975068

Start: 1375897

End: 1377084

Strand: Direct

Name: aspB [H]

Synonym: Bcer98_1268

Alternate gene names: 152975068

Gene position: 1375897-1377084 (Clockwise)

Preceding gene: 152975067

Following gene: 152975069

Centisome position: 33.67

GC content: 36.2

Gene sequence:

>1188_bases
ATGAAATTAGCAAAGCGAGTAGCTGCTTTAACACCGTCTGCAACTTTAGAGATTACAGCAAAGGCTCAGGTACTAAAGGC
CGAAGGGCATGATGTCATTGGTTTAGGAGCAGGAGAACCTGATTTTAATACGCCGGAGCATATTATAGATGCTGCACATA
AAGCGATGTTACAAGGACATACAAAATATACACCTACTGGTGGGTTACAAACGCTAAAACAAGAAATTGTAAAGAAATTT
ATGCGTGATCAAAAACTAACGTATGATCCGACAGAAATTATTATATGTAACGGTGCAAAACATTCACTTTATACACTCTT
TCAAGTATTGCTTGATGAAGGGGATGAAGTGATTATTCCAACTCCTTATTGGGTAAGTTATCCAGAACAAGTAAAACTTG
CTGGTGGAAAACCAGTTTATGTGGAAGGGTTAGAAGAGAATCAATATAAAATTACAGCAGAGCAGCTACGTGAAGCGATT
ACAGAGAAAACAAAAGCTGTTATTATTAATTCACCGAGCAATCCAACAGGAATGATTTATAGCAAGGAAGAATTAAAACA
GCTTGGAGAAGTATGCTTAGAACATGACATTTTAATTGTTTCTGATGAAATTTATGAAAAGTTAGTTTATGGCGGAGTAG
AATATACTTCAATTGCTCAGCTTTCTAATGAATTGAAAGAACAAACGATTATTATAAATGGTGTATCTAAATCACATTCT
ATGACAGGATGGCGAATTGGATATGCAGCAGGAAATAAGCAGCTTATTAAAGCAATGACCAATTTAGCAAGTCATAGTAC
ATCAAACCCTACTTCAATTGCTCAATACGGTGCAATTGCTGCATATGCAGGGCCACAAGAACCTGTGGAAATGATGCGAC
AAGCATTCGAAGAAAGATTAAACATTATTTATAATAAATTAATTCAAGTTCCTGGTTTCACTTGTATCAAACCACAAGGC
GCATTTTACTTATTTCCAAATGTAAAAGAAGCGGTAGCACTAGCTGGATACAAAACAGTAGATGAATGGGCAAAAGCGCT
GTTAGAGGAAGAAAAAGTAGCACTTGTTCCTGGAACAGGATTTGGTGCTCCAAACAATGTTCGTTTATCATATGCTACAT
CTCTTGAGCAATTAGAGAAAGCTTTAGAACGAATTCATACATTTATGAAAGGTAAAGTGCAGGCTTAA

Upstream 100 bases:

>100_bases
ATCAAGAAGGTCGTTATAAGTATTATTATTTGAGATTTCAAGATGGGGAATTTGCTGCATTTTACAGCATTGAAAAATAG
ATACAGGGGGAAAACCGCAA

Downstream 100 bases:

>100_bases
AAAGAATATTTTGGATTTGCACTTTTGAACAAATGAACATGACCTCCCTATATAGGGAGGTTTTTTGACGAATTGTGGAA
AAAGAAATGCTATGAGGTTG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKLAKRVAALTPSATLEITAKAQVLKAEGHDVIGLGAGEPDFNTPEHIIDAAHKAMLQGHTKYTPTGGLQTLKQEIVKKF
MRDQKLTYDPTEIIICNGAKHSLYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENQYKITAEQLREAI
TEKTKAVIINSPSNPTGMIYSKEELKQLGEVCLEHDILIVSDEIYEKLVYGGVEYTSIAQLSNELKEQTIIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGPQEPVEMMRQAFEERLNIIYNKLIQVPGFTCIKPQG
AFYLFPNVKEAVALAGYKTVDEWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQLEKALERIHTFMKGKVQA

Sequences:

>Translated_395_residues
MKLAKRVAALTPSATLEITAKAQVLKAEGHDVIGLGAGEPDFNTPEHIIDAAHKAMLQGHTKYTPTGGLQTLKQEIVKKF
MRDQKLTYDPTEIIICNGAKHSLYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENQYKITAEQLREAI
TEKTKAVIINSPSNPTGMIYSKEELKQLGEVCLEHDILIVSDEIYEKLVYGGVEYTSIAQLSNELKEQTIIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGPQEPVEMMRQAFEERLNIIYNKLIQVPGFTCIKPQG
AFYLFPNVKEAVALAGYKTVDEWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQLEKALERIHTFMKGKVQA
>Mature_395_residues
MKLAKRVAALTPSATLEITAKAQVLKAEGHDVIGLGAGEPDFNTPEHIIDAAHKAMLQGHTKYTPTGGLQTLKQEIVKKF
MRDQKLTYDPTEIIICNGAKHSLYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEENQYKITAEQLREAI
TEKTKAVIINSPSNPTGMIYSKEELKQLGEVCLEHDILIVSDEIYEKLVYGGVEYTSIAQLSNELKEQTIIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGPQEPVEMMRQAFEERLNIIYNKLIQVPGFTCIKPQG
AFYLFPNVKEAVALAGYKTVDEWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQLEKALERIHTFMKGKVQA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=324, Percent_Identity=29.6296296296296, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI169881279, Length=324, Percent_Identity=29.6296296296296, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI56713254, Length=342, Percent_Identity=28.9473684210526, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI56713256, Length=342, Percent_Identity=28.9473684210526, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=24.8663101604278, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI169881281, Length=321, Percent_Identity=25.2336448598131, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4885351, Length=378, Percent_Identity=25.6613756613757, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI215599424, Length=366, Percent_Identity=24.0437158469945, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI19263340, Length=374, Percent_Identity=24.0641711229947, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI187936925, Length=370, Percent_Identity=22.972972972973, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI14211921, Length=370, Percent_Identity=22.972972972973, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI149944424, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=398, Percent_Identity=29.8994974874372, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788722, Length=391, Percent_Identity=28.9002557544757, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=25.5434782608696, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787909, Length=365, Percent_Identity=22.4657534246575, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790797, Length=391, Percent_Identity=24.5524296675192, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48994949, Length=312, Percent_Identity=24.6794871794872, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=418, Percent_Identity=30.1435406698565, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71994476, Length=418, Percent_Identity=30.1435406698565, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17567369, Length=398, Percent_Identity=28.643216080402, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=27.4666666666667, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322401, Length=393, Percent_Identity=29.7709923664122, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=25.8823529411765, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323118, Length=342, Percent_Identity=27.7777777777778, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28573069, Length=295, Percent_Identity=31.1864406779661, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646114, Length=295, Percent_Identity=31.1864406779661, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573067, Length=295, Percent_Identity=31.1864406779661, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573065, Length=295, Percent_Identity=31.1864406779661, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=25.4691689008043, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=22.2784810126582, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43546; Mature: 43546

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAKRVAALTPSATLEITAKAQVLKAEGHDVIGLGAGEPDFNTPEHIIDAAHKAMLQGH
CCHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTGGLQTLKQEIVKKFMRDQKLTYDPTEIIICNGAKHSLYTLFQVLLDEGDEVIIP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVYVEGLEENQYKITAEQLREAITEKTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEE
SKEELKQLGEVCLEHDILIVSDEIYEKLVYGGVEYTSIAQLSNELKEQTIIINGVSKSHS
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCC
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGPQEPVEMMRQAFEERL
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHHH
NIIYNKLIQVPGFTCIKPQGAFYLFPNVKEAVALAGYKTVDEWAKALLEEEKVALVPGTG
HHHHHHHHHCCCCEEECCCCCEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCC
FGAPNNVRLSYATSLEQLEKALERIHTFMKGKVQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLAKRVAALTPSATLEITAKAQVLKAEGHDVIGLGAGEPDFNTPEHIIDAAHKAMLQGH
CCHHHHHHHCCCCCEEEEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTGGLQTLKQEIVKKFMRDQKLTYDPTEIIICNGAKHSLYTLFQVLLDEGDEVIIP
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVYVEGLEENQYKITAEQLREAITEKTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEE
SKEELKQLGEVCLEHDILIVSDEIYEKLVYGGVEYTSIAQLSNELKEQTIIINGVSKSHS
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCC
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGPQEPVEMMRQAFEERL
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHHH
NIIYNKLIQVPGFTCIKPQGAFYLFPNVKEAVALAGYKTVDEWAKALLEEEKVALVPGTG
HHHHHHHHHCCCCEEECCCCCEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCC
FGAPNNVRLSYATSLEQLEKALERIHTFMKGKVQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]