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The map label for this gene is aroA

Identifier: 152975042

GI number: 152975042

Start: 1352628

End: 1353902

Strand: Direct

Name: aroA

Synonym: Bcer98_1242

Alternate gene names: 152975042

Gene position: 1352628-1353902 (Clockwise)

Preceding gene: 152975041

Following gene: 152975043

Centisome position: 33.1

GC content: 39.14

Gene sequence:

>1275_bases
ATGGCAAATATAAGGCGAGAAAAAGGGTTAAATGGAACGATTGCGATACCTGGAGATAAATCGATTTCACATCGCGCTGT
CATGTTTGGAGCGATAGCGGAAGGTACAACAAAAGTTTCAAATTTTTTATTAGGAGAAGATTGTTTAAGTACCATTGCAT
GTTTTCGAAAACTCGGTGTGAAAATTGATCAAAGTGGAAATGATGTCACGATATATGGAAAAGGATTAACTGGATTGCAA
GAGCCCAAAGAGGTATTAGATGTGGGAAATTCGGGAACGACCATTCGCCTTATGCTCGGTATTTTAGCAAATGTACCTTT
CCATTGTACAATCATAGGCGACGATTCTATTGGAAAACGTCCTATGAAACGTGTTACAGATCCTCTTCGTGAAATGAATG
CACAAATAGATGGTCGAGAAGATGGACAATATACGCCATTATCGATTCGAGGCGGGAATATAAAAGGGATACATTATGAT
TCTCCTGTTGCAAGTGCACAAGTAAAATCAGCAATTTTACTTGCTGGATTAAAAGGAGAGGGCGTTACAACAGTAACGGA
ACCACTACAATCACGCGATCATACTGAGCGTATGCTCCGTGCATTTGGCTGTACAGTGGAAGTAACGGGCCAAACAGTTT
CACTGCGAGGAGGACAATCCCTCATAGGGACGGAGATTGAAGTGCCTGGTGATATTTCTTCAGCAGCCTTTTTCTTAGTT
GCAGGTGCGATTGTTCCGAATAGTAAAATCGTCTTGAAAAATGTTGGCTTAAATCCAACGAGAACAGGGATTATAGACGT
TTTACAAAAAATGGGGGCAATTCTTTCGGTTGATCATGTACGAAATGAAGAATTTGAGCCATGTGGAGATATTACAATTG
AAACTTCAAAATTACAAGGAATCGAAATTGGAGGCTCGTTAATTCCAAGATTAATTGATGAAATTCCTATTATTGCTTTA
CTAGCGACACAGGCAACTGGCACAACCGTTATTAAAGATGCTGAAGAATTAAAAGTAAAAGAAACAAATCGTATTGATAC
AGTTGTACAAGAACTAAAAAAGCTAGGCGTAAAAATTGAAGCGACATCAGATGGTATGATTATATATGGAAATCAGAAGC
TACAAGGAGGGATTGTTGATAGTCATGGGGATCATCGCATTGGGATGATGCTTGCGATTGCTTCTTGTATCGCTGATGGC
GAGGTTGAAATACAAAGAAGTGATGCGGTTTCTGTATCTTATCCAAACTTTTTTGATCAGTTGGCATCTTTGTAA

Upstream 100 bases:

>100_bases
AAAAGTTTCGTTTTATGTGTTTGCACGGCAGAGAAAGAAAGCTGTACAATAAAGATAGATAATACATATATAAGTAAGTA
CACATATAGGAGGGCAAAGG

Downstream 100 bases:

>100_bases
AGAAAAGGAAGGCACTTTCTTTGAGAAAATTCTTTTCCATTTCTTTTAGTTGCTTAGTAGTCAACTGTTGTTTATGATTA
AGTGAATAGATGAGAATATT

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGVKIDQSGNDVTIYGKGLTGLQ
EPKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKRPMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYD
SPVASAQVKSAILLAGLKGEGVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLV
AGAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQGIEIGGSLIPRLIDEIPIIAL
LATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIEATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADG
EVEIQRSDAVSVSYPNFFDQLASL

Sequences:

>Translated_424_residues
MANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGVKIDQSGNDVTIYGKGLTGLQ
EPKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKRPMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYD
SPVASAQVKSAILLAGLKGEGVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLV
AGAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQGIEIGGSLIPRLIDEIPIIAL
LATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIEATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADG
EVEIQRSDAVSVSYPNFFDQLASL
>Mature_423_residues
ANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGVKIDQSGNDVTIYGKGLTGLQE
PKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKRPMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYDS
PVASAQVKSAILLAGLKGEGVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLVA
GAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQGIEIGGSLIPRLIDEIPIIALL
ATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIEATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADGE
VEIQRSDAVSVSYPNFFDQLASL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family

Homologues:

Organism=Escherichia coli, GI1787137, Length=429, Percent_Identity=30.3030303030303, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6320332, Length=465, Percent_Identity=24.3010752688172, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROA_BACCN (A7GN56)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001374559.1
- ProteinModelPortal:   A7GN56
- SMR:   A7GN56
- STRING:   A7GN56
- EnsemblBacteria:   EBBACT00000039048
- GeneID:   5345185
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_1242
- eggNOG:   COG0128
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG646626
- OMA:   PAPSRDH
- ProtClustDB:   PRK02427
- BioCyc:   BCER315749:BCER98_1242-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00210
- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792
- Gene3D:   G3DSA:3.65.10.10
- PIRSF:   PIRSF000505
- TIGRFAMs:   TIGR01356

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.19

Molecular weight: Translated: 45229; Mature: 45098

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00104 EPSP_SYNTHASE_1; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGV
CCCCCCCCCCCCEEEECCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
KIDQSGNDVTIYGKGLTGLQEPKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKR
EEECCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCC
PMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYDSPVASAQVKSAILLAGLKGE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHEEEEEECCCC
GVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLV
CCCHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEECCCCCCCCCEEECCCCCHHHHHHHH
AGAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQG
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHEEHHHHCCCCCCCCCCEEEEECCCCC
IEIGGSLIPRLIDEIPIIALLATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIE
EEECHHHHHHHHHHCCEEEEEECCCCCCEEECCHHHHEECCCCHHHHHHHHHHHCCEEEE
ATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADGEVEIQRSDAVSVSYPNFFDQ
ECCCCEEEECCCEECCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHHH
LASL
HHCC
>Mature Secondary Structure 
ANIRREKGLNGTIAIPGDKSISHRAVMFGAIAEGTTKVSNFLLGEDCLSTIACFRKLGV
CCCCCCCCCCCEEEECCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
KIDQSGNDVTIYGKGLTGLQEPKEVLDVGNSGTTIRLMLGILANVPFHCTIIGDDSIGKR
EEECCCCEEEEEECCCCCCCCCHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCC
PMKRVTDPLREMNAQIDGREDGQYTPLSIRGGNIKGIHYDSPVASAQVKSAILLAGLKGE
HHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCCCCHHHHHHHEEEEEECCCC
GVTTVTEPLQSRDHTERMLRAFGCTVEVTGQTVSLRGGQSLIGTEIEVPGDISSAAFFLV
CCCHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEECCCCCCCCCEEECCCCCHHHHHHHH
AGAIVPNSKIVLKNVGLNPTRTGIIDVLQKMGAILSVDHVRNEEFEPCGDITIETSKLQG
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCHHEEHHHHCCCCCCCCCCEEEEECCCCC
IEIGGSLIPRLIDEIPIIALLATQATGTTVIKDAEELKVKETNRIDTVVQELKKLGVKIE
EEECHHHHHHHHHHCCEEEEEECCCCCCEEECCHHHHEECCCCHHHHHHHHHHHCCEEEE
ATSDGMIIYGNQKLQGGIVDSHGDHRIGMMLAIASCIADGEVEIQRSDAVSVSYPNFFDQ
ECCCCEEEECCCEECCCEECCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCHHHHH
LASL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA