Click here to switch to the map view.

The map label for this gene is gltT [H]

Identifier: 152974956

GI number: 152974956

Start: 1264705

End: 1265976

Strand: Direct

Name: gltT [H]

Synonym: Bcer98_1153

Alternate gene names: 152974956

Gene position: 1264705-1265976 (Clockwise)

Preceding gene: 152974954

Following gene: 152974957

Centisome position: 30.94

GC content: 36.24

Gene sequence:

>1272_bases
ATGAAGAGGATTGGACTTGCATGGCAAATATTAATAGGGCTTGCACTCGGTATTGCAGTTGGGGCGATTTTTTATGGCAA
TCCAGAGGTTGCAAAGTTTTTACAACCAATTGGTGATATTTTTATTCGATTAATTAAGATGATTGTTGTACCAATCGTTG
TAGCGAGCATCGTTGTTGGGGTTGCAGGTGTTGGAGATGTGAAAAAGCTAGGTCGATTAGGCGGAAAAACAATTATTTAT
TTTGAGATTATTACAACAATTGCGATTGTTGTCGGCTTGCTGGTAGCGAATATTTTCCAACCAGGAAAAGGTATTAATAT
GAATGAATTAACAAAAACAGATATTTCAAAATATACAGCTACAACTGAGCAAGTACAGAGTCATTCATTTGCGGATACAT
TTGTAAACATTGTTCCGACAAATATTATAGAATCACTGGCAAAAGGTGATATGCTTGCTATTATTTTCTTCTCTGTATTA
TTTGGTTTAGGGATTGCAGCGATTGGTGAAAGAGGAAAACCGGTTCTGCAATTTTTCCAAGGGGTAGCAGATGCAATGTT
TTATGTTACAAACCAAGTAATGAAGTTTGCACCATTTGGGGTATTTGCTTTAATTGGTGTGACCGTTTCTAAATTTGGTC
TAGCATCATTAATCCCACTAGGGAAGTTAGTGATTGTTGTGTATGGATCGATGATTTTCTTTGTTGTTGTCGTACTAGGA
CTTACAGCGAAAATCTTTGGAATTAACATATTTCAGTTCTTTAAAATTTTAAAAGATGAGCTTATTTTAGCGTATTCTAC
AGCGAGCTCAGAAACAGTTTTGCCAAAAATTATGGAGAAGATGGAGAAATTCGGCTGTCCAAAGGCGATTTCATCTTTCG
TTATTCCAACTGGTTATTCATTTAACCTAGATGGATCAACGCTATACCAAGCGATTGCTGCAATTTTCTTAGCACAAATG
TATGGTATTGATTTATCGATTACACAGCAAATTACATTGTTACTTGTATTAATGTTAACATCAAAAGGGATTGCAGGGGT
ACCAGGTGTATCATTCGTTGTACTATTAGCAACGTTAGGTACAGTTGGAATTCCGGCAGAAGGTTTAGCGTTTATCGCAG
GTATTGACCGTATTTTAGATATGGCACGTACAGCAGTTAACGTTGTTGGAAACTCTTTAGCAGCTGTTGTTATGTCTAAA
TGGGAAGGACAATATGATGATATAAAAGGACAAGCTTATTTGAAAGAGATATCTGGAAAACAAGTAGCGTAA

Upstream 100 bases:

>100_bases
ACAAATGTAGTGAATTGTCGAATTATATGTAATACGCTTAATTTCTTTATTTCATAGAAAAATAGAGTTATAGCATCTAA
GAAGGGGGTTGGCAGCAAGT

Downstream 100 bases:

>100_bases
TAACGATTGAAAAAGCTCTCGCATCAATATGTGGGAGCTTTTCTATATTGGAAAGGAGTGGGATGTATAATGAAGAGAAA
ATATGGAAATGGTGCTTCGT

Product: sodium:dicarboxylate symporter

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKRIGLAWQILIGLALGIAVGAIFYGNPEVAKFLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIVVGLLVANIFQPGKGINMNELTKTDISKYTATTEQVQSHSFADTFVNIVPTNIIESLAKGDMLAIIFFSVL
FGLGIAAIGERGKPVLQFFQGVADAMFYVTNQVMKFAPFGVFALIGVTVSKFGLASLIPLGKLVIVVYGSMIFFVVVVLG
LTAKIFGINIFQFFKILKDELILAYSTASSETVLPKIMEKMEKFGCPKAISSFVIPTGYSFNLDGSTLYQAIAAIFLAQM
YGIDLSITQQITLLLVLMLTSKGIAGVPGVSFVVLLATLGTVGIPAEGLAFIAGIDRILDMARTAVNVVGNSLAAVVMSK
WEGQYDDIKGQAYLKEISGKQVA

Sequences:

>Translated_423_residues
MKRIGLAWQILIGLALGIAVGAIFYGNPEVAKFLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIVVGLLVANIFQPGKGINMNELTKTDISKYTATTEQVQSHSFADTFVNIVPTNIIESLAKGDMLAIIFFSVL
FGLGIAAIGERGKPVLQFFQGVADAMFYVTNQVMKFAPFGVFALIGVTVSKFGLASLIPLGKLVIVVYGSMIFFVVVVLG
LTAKIFGINIFQFFKILKDELILAYSTASSETVLPKIMEKMEKFGCPKAISSFVIPTGYSFNLDGSTLYQAIAAIFLAQM
YGIDLSITQQITLLLVLMLTSKGIAGVPGVSFVVLLATLGTVGIPAEGLAFIAGIDRILDMARTAVNVVGNSLAAVVMSK
WEGQYDDIKGQAYLKEISGKQVA
>Mature_423_residues
MKRIGLAWQILIGLALGIAVGAIFYGNPEVAKFLQPIGDIFIRLIKMIVVPIVVASIVVGVAGVGDVKKLGRLGGKTIIY
FEIITTIAIVVGLLVANIFQPGKGINMNELTKTDISKYTATTEQVQSHSFADTFVNIVPTNIIESLAKGDMLAIIFFSVL
FGLGIAAIGERGKPVLQFFQGVADAMFYVTNQVMKFAPFGVFALIGVTVSKFGLASLIPLGKLVIVVYGSMIFFVVVVLG
LTAKIFGINIFQFFKILKDELILAYSTASSETVLPKIMEKMEKFGCPKAISSFVIPTGYSFNLDGSTLYQAIAAIFLAQM
YGIDLSITQQITLLLVLMLTSKGIAGVPGVSFVVLLATLGTVGIPAEGLAFIAGIDRILDMARTAVNVVGNSLAAVVMSK
WEGQYDDIKGQAYLKEISGKQVA

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI40254478, Length=475, Percent_Identity=27.1578947368421, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI169790839, Length=475, Percent_Identity=28, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI21314632, Length=421, Percent_Identity=28.2660332541568, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI4827012, Length=458, Percent_Identity=26.4192139737991, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI66773030, Length=471, Percent_Identity=27.6008492569002, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI194239697, Length=441, Percent_Identity=26.984126984127, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI5032093, Length=434, Percent_Identity=26.9585253456221, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI262359914, Length=392, Percent_Identity=27.2959183673469, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI223468564, Length=276, Percent_Identity=27.1739130434783, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI223468566, Length=276, Percent_Identity=27.1739130434783, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI301601644, Length=185, Percent_Identity=31.8918918918919, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790514, Length=430, Percent_Identity=61.3953488372093, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1789947, Length=405, Percent_Identity=40.9876543209877, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI1788024, Length=413, Percent_Identity=27.6029055690073, Blast_Score=118, Evalue=8e-28,
Organism=Escherichia coli, GI1789473, Length=285, Percent_Identity=23.859649122807, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537407, Length=426, Percent_Identity=29.1079812206573, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI71996953, Length=439, Percent_Identity=27.5626423690205, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193206505, Length=455, Percent_Identity=27.9120879120879, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71983099, Length=438, Percent_Identity=26.4840182648402, Blast_Score=155, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI71983106, Length=438, Percent_Identity=26.4840182648402, Blast_Score=155, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI17541374, Length=405, Percent_Identity=26.4197530864197, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI193206654, Length=420, Percent_Identity=24.5238095238095, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24583025, Length=404, Percent_Identity=24.7524752475248, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI17137668, Length=404, Percent_Identity=24.7524752475248, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24583023, Length=404, Percent_Identity=24.7524752475248, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI281360483, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137666, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360481, Length=442, Percent_Identity=24.6606334841629, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 45189; Mature: 45189

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1 ; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1359385 [H]