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The map label for this gene is ndhF [H]

Identifier: 152974910

GI number: 152974910

Start: 1217268

End: 1218800

Strand: Direct

Name: ndhF [H]

Synonym: Bcer98_1106

Alternate gene names: 152974910

Gene position: 1217268-1218800 (Clockwise)

Preceding gene: 152974909

Following gene: 152974911

Centisome position: 29.78

GC content: 37.18

Gene sequence:

>1533_bases
ATGTTAATTTCGCTAAATTCATCAACACTATTAACATTATTGTTCATTACGCTTAGTGCTTCTTTGCTAAGTGGATTATT
GTTTTTAAATTCAAGGATACCCTTACATTTTGTTCGTATTCATATTGGCATCGCTGCTTTACCATCATTCGTTTCCTTAC
TTGCACTTATTCATACAAATGTAGATGGAGTTATTGGTCCTTGGCATCTAGATTCTTTAGCTTGGTTAATGGCTTTCTTT
GTTCTTACAATTGGTTTTATCATTCAGCGTTTTTCTTTACGTTACTTAATGGGAGATCGCTCATATCGAAAATATTTTAT
ACTTTTCACATTCACTACAGGCGCCTCTTCCATTGCATGGTTAAGTAATGATCTTCGTTTAATGGTCATTTGTTGGGGAG
TAACTCTTGTCGGATTGCTCCTACTCATAAGATTAAATAGCAGTTGGAAAGTGGTAAGTGAAGCAACGAAAATTTCTGGT
CGTTTATTTACAATAAGTTGGGTGGCTCTATTATTAGCTGTCATTTGGCTTTCTCAAGTAACTGGCCAGTGGCAGTTAAC
ATCCGTTTTAGGGGATGAAAGTTTAGCTCAATATGGAAAATGGGAGAAAGCGGGGATTAACCTATTAATCCTATTAGCTG
TGATGATTCCGGCAGCCCAATGGCCTTTCCAACGATGGCTCATTGAATCTGCTATTGCTCCAACTCCTGTTTCCGCTATT
ATGCATGCAGGTTTAGTAAATGCTGGCGGTATCATGCTAACTAGATTTTCACCTCTTTTTCATGATGATATAGCACAAAT
TATTTTACTTATTTTCTCTAGTATCTCTGTATTAATAGGAACTGGAATTAGTCTAGTCCAAGTTGACTACAAACGTCAGC
TAGTGGGTTCAACGATTGCACAAATGGGATTTATGCTCATTCAATGCGCATTGGGTGCTTATTTAGCTGCCATTATTCAT
TTAATTTTACATGGTCTGTTCAAAGCTACATTGTTTTTACAAGCTGGTTCTTCCGTACGCCATTTTGAGGTTGTGAAACA
CTCTCATGAAAAGGCATCGTATTTATGGATTATGATTGGACGTATTTTAGGCTTACTTATAGCAATTGGTTTCTGGCTTA
TGACTCCTAAAGAGGGATATCAATTGGTGAGTGCGCTAATCTTAGGATGGTCATTATACTTTTCATGGAAACAGCTTGTT
GTTTTCGGAGAGGGAAAAATTGGTCGAATTGCTGGCTTATCTTTTTTGATTGGATTTTCGCTCATTTACTTTACCGTTCA
TACCCTTTTTTATGAGTGGTTGCATACAGATGTGTATCAAAATGTTCAACCTCCAGTTCTAGCTATTACCTTTGTTATCT
GTCTCTTACTATTTGGTAGCGCTATTGTTGCTTTGGTTGCTCGCAATCGATCCTTTACTATATTCGCTATATTATACCTT
TGGTTAGTTCGAGTAGGCGAGGCAAATCAAAAGTCAGTAGAAAGTCACCCTAACTACTTGAAACACTATGTATCACAGGG
AGGTAATCAGTGA

Upstream 100 bases:

>100_bases
TATTCGCTAAAAGAAGGAAATGAAGATTTGAAATTCTGAAAAATTACCTTGATGAAACAGAAGTTTGTATAAGTTCGTCG
TTGGGAAGGGAGTAAGTTAA

Downstream 100 bases:

>100_bases
TGAGCGTATCATCTGTAGTAACGAAAGAAAGTTTTAAAAAGAAAGACGTAAATATGAATATTCAGGAAAAGGATATAAAT
GATTTCGTTCAATCTGCTAG

Product: NADH dehydrogenase subunit 5

Products: NA

Alternate protein names: NADH dehydrogenase subunit 5 [H]

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MLISLNSSTLLTLLFITLSASLLSGLLFLNSRIPLHFVRIHIGIAALPSFVSLLALIHTNVDGVIGPWHLDSLAWLMAFF
VLTIGFIIQRFSLRYLMGDRSYRKYFILFTFTTGASSIAWLSNDLRLMVICWGVTLVGLLLLIRLNSSWKVVSEATKISG
RLFTISWVALLLAVIWLSQVTGQWQLTSVLGDESLAQYGKWEKAGINLLILLAVMIPAAQWPFQRWLIESAIAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVRHFEVVKHSHEKASYLWIMIGRILGLLIAIGFWLMTPKEGYQLVSALILGWSLYFSWKQLV
VFGEGKIGRIAGLSFLIGFSLIYFTVHTLFYEWLHTDVYQNVQPPVLAITFVICLLLFGSAIVALVARNRSFTIFAILYL
WLVRVGEANQKSVESHPNYLKHYVSQGGNQ

Sequences:

>Translated_510_residues
MLISLNSSTLLTLLFITLSASLLSGLLFLNSRIPLHFVRIHIGIAALPSFVSLLALIHTNVDGVIGPWHLDSLAWLMAFF
VLTIGFIIQRFSLRYLMGDRSYRKYFILFTFTTGASSIAWLSNDLRLMVICWGVTLVGLLLLIRLNSSWKVVSEATKISG
RLFTISWVALLLAVIWLSQVTGQWQLTSVLGDESLAQYGKWEKAGINLLILLAVMIPAAQWPFQRWLIESAIAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVRHFEVVKHSHEKASYLWIMIGRILGLLIAIGFWLMTPKEGYQLVSALILGWSLYFSWKQLV
VFGEGKIGRIAGLSFLIGFSLIYFTVHTLFYEWLHTDVYQNVQPPVLAITFVICLLLFGSAIVALVARNRSFTIFAILYL
WLVRVGEANQKSVESHPNYLKHYVSQGGNQ
>Mature_510_residues
MLISLNSSTLLTLLFITLSASLLSGLLFLNSRIPLHFVRIHIGIAALPSFVSLLALIHTNVDGVIGPWHLDSLAWLMAFF
VLTIGFIIQRFSLRYLMGDRSYRKYFILFTFTTGASSIAWLSNDLRLMVICWGVTLVGLLLLIRLNSSWKVVSEATKISG
RLFTISWVALLLAVIWLSQVTGQWQLTSVLGDESLAQYGKWEKAGINLLILLAVMIPAAQWPFQRWLIESAIAPTPVSAI
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIAQMGFMLIQCALGAYLAAIIH
LILHGLFKATLFLQAGSSVRHFEVVKHSHEKASYLWIMIGRILGLLIAIGFWLMTPKEGYQLVSALILGWSLYFSWKQLV
VFGEGKIGRIAGLSFLIGFSLIYFTVHTLFYEWLHTDVYQNVQPPVLAITFVICLLLFGSAIVALVARNRSFTIFAILYL
WLVRVGEANQKSVESHPNYLKHYVSQGGNQ

Specific function: Ndh-1 Shuttles Electrons From NADH, Via Fmn And Iron- Sulfur (Fe-S) Centers, To Quinones In The Respiratory Chain. The Immediate Electron Acceptor For The Enzyme In This Species Is Believed To Be Ubiquinone. Couples The Redox Reaction To Proton Translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=286, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1788614, Length=283, Percent_Identity=29.6819787985866, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788831, Length=125, Percent_Identity=33.6, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1788829, Length=296, Percent_Identity=27.3648648648649, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 56832; Mature: 56832

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLISLNSSTLLTLLFITLSASLLSGLLFLNSRIPLHFVRIHIGIAALPSFVSLLALIHTN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCC
VDGVIGPWHLDSLAWLMAFFVLTIGFIIQRFSLRYLMGDRSYRKYFILFTFTTGASSIAW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHH
LSNDLRLMVICWGVTLVGLLLLIRLNSSWKVVSEATKISGRLFTISWVALLLAVIWLSQV
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TGQWQLTSVLGDESLAQYGKWEKAGINLLILLAVMIPAAQWPFQRWLIESAIAPTPVSAI
CCCEEEHHHHCHHHHHHCCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIA
HHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAIIHLILHGLFKATLFLQAGSSVRHFEVVKHSHEKASYLWIMIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
RILGLLIAIGFWLMTPKEGYQLVSALILGWSLYFSWKQLVVFGEGKIGRIAGLSFLIGFS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
LIYFTVHTLFYEWLHTDVYQNVQPPVLAITFVICLLLFGSAIVALVARNRSFTIFAILYL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WLVRVGEANQKSVESHPNYLKHYVSQGGNQ
HHHHHCCCCHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MLISLNSSTLLTLLFITLSASLLSGLLFLNSRIPLHFVRIHIGIAALPSFVSLLALIHTN
CEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCC
VDGVIGPWHLDSLAWLMAFFVLTIGFIIQRFSLRYLMGDRSYRKYFILFTFTTGASSIAW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHH
LSNDLRLMVICWGVTLVGLLLLIRLNSSWKVVSEATKISGRLFTISWVALLLAVIWLSQV
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
TGQWQLTSVLGDESLAQYGKWEKAGINLLILLAVMIPAAQWPFQRWLIESAIAPTPVSAI
CCCEEEHHHHCHHHHHHCCCCHHCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHH
MHAGLVNAGGIMLTRFSPLFHDDIAQIILLIFSSISVLIGTGISLVQVDYKRQLVGSTIA
HHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHH
QMGFMLIQCALGAYLAAIIHLILHGLFKATLFLQAGSSVRHFEVVKHSHEKASYLWIMIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHH
RILGLLIAIGFWLMTPKEGYQLVSALILGWSLYFSWKQLVVFGEGKIGRIAGLSFLIGFS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHH
LIYFTVHTLFYEWLHTDVYQNVQPPVLAITFVICLLLFGSAIVALVARNRSFTIFAILYL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WLVRVGEANQKSVESHPNYLKHYVSQGGNQ
HHHHHCCCCHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]