Click here to switch to the map view.

The map label for this gene is queC [H]

Identifier: 152974868

GI number: 152974868

Start: 1180788

End: 1181450

Strand: Direct

Name: queC [H]

Synonym: Bcer98_1064

Alternate gene names: 152974868

Gene position: 1180788-1181450 (Clockwise)

Preceding gene: 152974867

Following gene: 152974869

Centisome position: 28.89

GC content: 37.56

Gene sequence:

>663_bases
ATGAAAAAAGAGAAAGCAGTTGTTGTTTTTAGTGGTGGTCAAGATAGTACAACTTGTTTATTTTGGGCTATGCAACAGTT
TGCAGAAGTAGAGGCTGTAACGTTCAACTATAATCAACGTCATAAATTAGAAATTGAATGTGCAGCAAATATTGCAAAGG
AATTAGGAATTAAGCATACAGTACTAGATATGAGCCTTTTAAATCAACTTGCTCCCAATGCTTTAACAAGAACAGATATC
GATATTACGCATGAAGAAGGTGAATTACCATCTACCTTTGTTGAGGGACGAAATTTACTGTTCTTATCATTTGCAGCTGT
TTTAGCGAAACAAGTAGGAGCACGTCATATTGTAACTGGCGTGTGCGAAACAGATTTTAGTGGCTATCCTGATTGCCGTG
ATGCATTTGTAAAGTCATTAAATGTTACCTTAAATTTATCTATGGATTATCCGTTTGTCATTCATACTCCGCTTATGTGG
ATTGATAAGGCGGACACATGGAAGCTATCAGATGAATTAGGTGCATTTGATTTTGTGAGAGAAAAGACTTTAACGTGTTA
TAACGGAATCATTGGCGATGGATGCGGTGAATGTCCAGCATGTCAACTTCGCAAAGCAGGTTTAGATACGTACCTACAAG
AACGTGAAGGAGCGAAGGCATAA

Upstream 100 bases:

>100_bases
TGAGAACAACAATATCTTAAGGTATTGTTTTGTTTTTTTATTATGATAGTTCAAGAACGTTCTTTCTTCTTATTTATAAT
AGAGAAGGAGAATGAGTAAA

Downstream 100 bases:

>100_bases
TGGAACAAAGTTTTTTTGGGTTTCGTGTTGTAGAAAACTTACAAAAAATAGATAAGGATATTCAGCGTCAGCAATTAAAA
TATCATAATAAACGCGTAAT

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MKKEKAVVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLEIECAANIAKELGIKHTVLDMSLLNQLAPNALTRTDI
DITHEEGELPSTFVEGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDAFVKSLNVTLNLSMDYPFVIHTPLMW
IDKADTWKLSDELGAFDFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGAKA

Sequences:

>Translated_220_residues
MKKEKAVVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLEIECAANIAKELGIKHTVLDMSLLNQLAPNALTRTDI
DITHEEGELPSTFVEGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDAFVKSLNVTLNLSMDYPFVIHTPLMW
IDKADTWKLSDELGAFDFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGAKA
>Mature_220_residues
MKKEKAVVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLEIECAANIAKELGIKHTVLDMSLLNQLAPNALTRTDI
DITHEEGELPSTFVEGRNLLFLSFAAVLAKQVGARHIVTGVCETDFSGYPDCRDAFVKSLNVTLNLSMDYPFVIHTPLMW
IDKADTWKLSDELGAFDFVREKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGAKA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=216, Percent_Identity=57.8703703703704, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24453; Mature: 24453

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKAVVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLEIECAANIAKELGIKHT
CCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHCCCHHH
VLDMSLLNQLAPNALTRTDIDITHEEGELPSTFVEGRNLLFLSFAAVLAKQVGARHIVTG
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHE
VCETDFSGYPDCRDAFVKSLNVTLNLSMDYPFVIHTPLMWIDKADTWKLSDELGAFDFVR
HHCCCCCCCCCHHHHHHHHCCEEEEEECCCCEEEECCEEEEECCCCEECHHHHCHHHHHH
EKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGAKA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKKEKAVVVFSGGQDSTTCLFWAMQQFAEVEAVTFNYNQRHKLEIECAANIAKELGIKHT
CCCCCEEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHCCCHHH
VLDMSLLNQLAPNALTRTDIDITHEEGELPSTFVEGRNLLFLSFAAVLAKQVGARHIVTG
HHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHE
VCETDFSGYPDCRDAFVKSLNVTLNLSMDYPFVIHTPLMWIDKADTWKLSDELGAFDFVR
HHCCCCCCCCCHHHHHHHHCCEEEEEECCCCEEEECCEEEEECCCCEECHHHHCHHHHHH
EKTLTCYNGIIGDGCGECPACQLRKAGLDTYLQEREGAKA
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA