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The map label for this gene is phnW

Identifier: 152974856

GI number: 152974856

Start: 1170174

End: 1171271

Strand: Direct

Name: phnW

Synonym: Bcer98_1052

Alternate gene names: 152974856

Gene position: 1170174-1171271 (Clockwise)

Preceding gene: 152974855

Following gene: 152974857

Centisome position: 28.63

GC content: 37.07

Gene sequence:

>1098_bases
ATGAAGAATCATCACTATTTATTATTAACGCCAGGGCCATTAACAACAACAAAAACCGTCAAGGAAGTAATGCTATACGA
TTGGTGCACATGGGATACAGAATATAACGAGTTAGTACAAGAAATACGAAAACGTCTTGTATCATTGGCGACGAAAGAAG
AGGAATATTATACAACTGTTTTCATGCAAGGAAGCGGTACATTCTCCGTAGAATCAGTTATTGGATCCGTGATTCCACAA
GAAGGAAAGCTACTTGTTTGTACGAATGGAGCATATGGAAAGCGAATCGTTCAAATAGCAACAACATTACATATTAATGT
TGTTGAGAGTTATACAAATGAATGGGAACCAACGAATCTTGCAGAAGTAGAAGAGATATTACAAAAAGACTCGGAAATTA
CGCATATTGCGGTGGTGCATTGTGAAACAACAACAGGAATAATCAATCCAATCGCTGATGTATGTCGGTTAGGAAAACAA
TATGGAAAAGTTACAATTGTGGATGCTATGAGTAGTTTTGGCGGAGTAGAAATGGATGTTGCTGATTTACAAATTGATTT
TATGATTAGCAGTGCAAATAAATGTATTCAAGGTGTTCCAGGATTTGGATTTGTCATTGCAAAGCGTACGGAGTTAGAAC
AATGTAAAGGAAGGGCTCGCTCTTTATCATTAGACCTTTATGACCAGTGGGAAACAATGGAACTTCAAAATGGGAAGTGG
CGTTTTACATCGCCAACTCATACTGTACGTGCATTTTATCAAGCCTTGCTCGAGTTAGAAGAAGAGGGGGGAGTGAAAGC
GCGAAATACCCGTTACCGTAACAATCAACAAGTATTAGTGAAGAGAATGAGAGAAGTTGGGTTTGAGCCATTGTTAGATG
AAGCATATCAGTCTCCTATTATTACATCTTTTCTATATCCAGGGGAAGGTTTTACATTTCAGCAGTTATATGAGGAGTTA
AAAGAGCATGGATTTGTTATTTATCCTGGAAAAATTTCAAAGGTAGATACATTCCGAATTGGGAATATTGGTGATGTGTA
TGAAAGTGATATTCATCAATTAGTAGATTGTATTTCTGAAGGAGTTGTAATTGGATGA

Upstream 100 bases:

>100_bases
GCGGCGCTCATTATGTAATCGAAACAATGAAAGAGTTACCTCAAGTAATCGAATATATCGAAAAACAAGAATTTATCATT
TCTTGAAAGGAGCATAAATT

Downstream 100 bases:

>100_bases
AAGTATTTTGTTTAAGCGTGCAAGTAAAACTTGTCGAGAAGCACATTTAGATTTCATACAATATTTATCTTTTGAAATGA
AAAAAACGTATTTTGCATAA

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MKNHHYLLLTPGPLTTTKTVKEVMLYDWCTWDTEYNELVQEIRKRLVSLATKEEEYYTTVFMQGSGTFSVESVIGSVIPQ
EGKLLVCTNGAYGKRIVQIATTLHINVVESYTNEWEPTNLAEVEEILQKDSEITHIAVVHCETTTGIINPIADVCRLGKQ
YGKVTIVDAMSSFGGVEMDVADLQIDFMISSANKCIQGVPGFGFVIAKRTELEQCKGRARSLSLDLYDQWETMELQNGKW
RFTSPTHTVRAFYQALLELEEEGGVKARNTRYRNNQQVLVKRMREVGFEPLLDEAYQSPIITSFLYPGEGFTFQQLYEEL
KEHGFVIYPGKISKVDTFRIGNIGDVYESDIHQLVDCISEGVVIG

Sequences:

>Translated_365_residues
MKNHHYLLLTPGPLTTTKTVKEVMLYDWCTWDTEYNELVQEIRKRLVSLATKEEEYYTTVFMQGSGTFSVESVIGSVIPQ
EGKLLVCTNGAYGKRIVQIATTLHINVVESYTNEWEPTNLAEVEEILQKDSEITHIAVVHCETTTGIINPIADVCRLGKQ
YGKVTIVDAMSSFGGVEMDVADLQIDFMISSANKCIQGVPGFGFVIAKRTELEQCKGRARSLSLDLYDQWETMELQNGKW
RFTSPTHTVRAFYQALLELEEEGGVKARNTRYRNNQQVLVKRMREVGFEPLLDEAYQSPIITSFLYPGEGFTFQQLYEEL
KEHGFVIYPGKISKVDTFRIGNIGDVYESDIHQLVDCISEGVVIG
>Mature_365_residues
MKNHHYLLLTPGPLTTTKTVKEVMLYDWCTWDTEYNELVQEIRKRLVSLATKEEEYYTTVFMQGSGTFSVESVIGSVIPQ
EGKLLVCTNGAYGKRIVQIATTLHINVVESYTNEWEPTNLAEVEEILQKDSEITHIAVVHCETTTGIINPIADVCRLGKQ
YGKVTIVDAMSSFGGVEMDVADLQIDFMISSANKCIQGVPGFGFVIAKRTELEQCKGRARSLSLDLYDQWETMELQNGKW
RFTSPTHTVRAFYQALLELEEEGGVKARNTRYRNNQQVLVKRMREVGFEPLLDEAYQSPIITSFLYPGEGFTFQQLYEEL
KEHGFVIYPGKISKVDTFRIGNIGDVYESDIHQLVDCISEGVVIG

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=295, Percent_Identity=23.3898305084746, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536281, Length=370, Percent_Identity=22.972972972973, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_BACCN (A7GMM0)

Other databases:

- EMBL:   CP000764
- RefSeq:   YP_001374373.1
- ProteinModelPortal:   A7GMM0
- SMR:   A7GMM0
- STRING:   A7GMM0
- EnsemblBacteria:   EBBACT00000036625
- GeneID:   5344129
- GenomeReviews:   CP000764_GR
- KEGG:   bcy:Bcer98_1052
- eggNOG:   COG0075
- GeneTree:   EBGT00050000000896
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- BioCyc:   BCER315749:BCER98_1052-MONOMER
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 41331; Mature: 41331

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHHYLLLTPGPLTTTKTVKEVMLYDWCTWDTEYNELVQEIRKRLVSLATKEEEYYTTV
CCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
FMQGSGTFSVESVIGSVIPQEGKLLVCTNGAYGKRIVQIATTLHINVVESYTNEWEPTNL
EEECCCCEEHHHHHHHHCCCCCCEEEEECCCCHHHHEEEHHHHEEEEHHHHCCCCCCCCH
AEVEEILQKDSEITHIAVVHCETTTGIINPIADVCRLGKQYGKVTIVDAMSSFGGVEMDV
HHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
ADLQIDFMISSANKCIQGVPGFGFVIAKRTELEQCKGRARSLSLDLYDQWETMELQNGKW
EHEEEEEEEECHHHHHHCCCCCEEEEEECCHHHHHCCHHHEEEEEECCCCCEEEECCCEE
RFTSPTHTVRAFYQALLELEEEGGVKARNTRYRNNQQVLVKRMREVGFEPLLDEAYQSPI
EECCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCC
ITSFLYPGEGFTFQQLYEELKEHGFVIYPGKISKVDTFRIGNIGDVYESDIHQLVDCISE
CEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
GVVIG
CEECC
>Mature Secondary Structure
MKNHHYLLLTPGPLTTTKTVKEVMLYDWCTWDTEYNELVQEIRKRLVSLATKEEEYYTTV
CCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
FMQGSGTFSVESVIGSVIPQEGKLLVCTNGAYGKRIVQIATTLHINVVESYTNEWEPTNL
EEECCCCEEHHHHHHHHCCCCCCEEEEECCCCHHHHEEEHHHHEEEEHHHHCCCCCCCCH
AEVEEILQKDSEITHIAVVHCETTTGIINPIADVCRLGKQYGKVTIVDAMSSFGGVEMDV
HHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEEE
ADLQIDFMISSANKCIQGVPGFGFVIAKRTELEQCKGRARSLSLDLYDQWETMELQNGKW
EHEEEEEEEECHHHHHHCCCCCEEEEEECCHHHHHCCHHHEEEEEECCCCCEEEECCCEE
RFTSPTHTVRAFYQALLELEEEGGVKARNTRYRNNQQVLVKRMREVGFEPLLDEAYQSPI
EECCCHHHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCC
ITSFLYPGEGFTFQQLYEELKEHGFVIYPGKISKVDTFRIGNIGDVYESDIHQLVDCISE
CEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHC
GVVIG
CEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA