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The map label for this gene is dppE [H]

Identifier: 152974714

GI number: 152974714

Start: 1020343

End: 1021980

Strand: Direct

Name: dppE [H]

Synonym: Bcer98_0902

Alternate gene names: 152974714

Gene position: 1020343-1021980 (Clockwise)

Preceding gene: 152974712

Following gene: 152974716

Centisome position: 24.97

GC content: 35.04

Gene sequence:

>1638_bases
ATGAGGAAAAAACTACCGATTTTCGTAGCATCTACGATGGCAGTAAGTATGGTGTTAGGGGCATGTAGTTATCAAAAAGA
TGAACCGAAGGCAAAAGGGACTAGCGGTAAAAGCGGTGCAAAGCAAGTCTTAAATTTAATTGAAACACAAGAAATTCCAA
CGATGGATCCAGCTTTATCAGCCGATTCGCTTTCTGCCGAAGTAATGAATAATACAATGGAAGGATTGTATCGCCTTGGA
AAAGGAGATAAATTAGTTCCAGGAATCGCGACAGAATTTAAAAAATCAGATGACGGTAAGAAATATACATTTACATTACG
GAAAGATGCGAAATGGTCTAACGGAGATCTTGTAACAGCGAAAGATTTTGAATATGCATGGAAGCGAGCAATTAATCCTG
ATACGGCTGCAAAATCTGCATATATGATGTACGATATAAAAAATGCTGAAAAGATTAATAAAAAAGAAATGGCACCGGAT
CAATTAGGGGTAAAAGCCATTAATGATTATACATTGGAAGTAGAATTAGAGCATGCTGTACCATATTTTGTAGACTTATT
AATATATCCTTTATTTTATCCTGTAAATGAAAAGTATGTAACAGAGCAAGGGGATAAATTTGGACTAGAAGCGAACACAA
CACTTTACAACGGTCCATTTGTATTGAGTGAGTGGAAACATGAGAGAAGCTTCCAGATGAAAAAGAATCCATCTTATTGG
GAGCATAAAGAAGTAAAATTAGAAGAAGTGAATTTTAATATTGTAAAAGACACAGCTACACCGATTAATTTATATGAAAC
AAAAGCGGTAGATCGTGCTATATTATTGGCAGAATTTATCGATAAATATAAAGGAAAACCAGACTTTAAAACATTTGAAG
AAACAACAGTATTCTTCCTTCGTTTAAATCAAAAAGATCCAGCATTAGCGAATAAAAATATTCGTAAGGCCATTTCGCTT
GCTTTTGATAGAAAACCATTTGTGGAGACAATCTTAAACAATGGATCTACAGCAGCAACAGGGTTAATCCCGGGAAATTT
CATGTTTGGGCCGAATAAAAAAGATTTCCGGGTGGAAAATGGTGACATTGTGAAACCAAATATAAAAGAAGCTCAAAAAT
ATTGGGAAGCGGGTAAAAAAGAGCTTGGTAAAAATGAAATTGAATTAGAATTATTAAATGAAGATGTGGAATTGTCGAAA
AAAACAGGTGAGTATTTAAAAGGGGAATTAGAAAAGAACTTACCAGGTTTAACGCTGAAAATAAAGCAACAACCATTTGC
GCAAAAATTAAAACTAGAAGGTGCTGGCGACTATGTCATGTCATTCACTGGTTGGAGTGCTGATTTTCCAGATCCAATTT
CATACCTTGATATGTTTGTAACAGGTGGCACACAAAATAAAATGGGATACTCGAATCCAAAATATGATGAAATAATTATG
AAGGCAAAGAAAAATGGGAACGATGCAAATGCTCGCTGGAAAAGCTTACTTACAGCAGAAAAGATGCTGCTAGAAGATGC
AGCGATTGTACCAGTATACCAGCGCGGAAGAGCGTATTTACAAAGAGAAACAGTTAAGGATCTATACTTTCATAAATATG
GAGGAGATTTAAGCTTTAAATGGACATCTGTTGAATAA

Upstream 100 bases:

>100_bases
AAAAAATTATATTTATGTGTATAATATAAATTGTTGGAATATACATATATTTCTTTTTGTTCGAAAATGAAAAGGTTAAC
ATTTGTAGGGGGATGGAATT

Downstream 100 bases:

>100_bases
TTAAATCATTTCGTTAAAAAGGAAGAAACAGGAGTCAAACGGCTCCTGTTTCTTAATACACACGTTTTTTATAAATATCG
TTTCCGCCTACTTGTTTCCA

Product: extracellular solute-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MRKKLPIFVASTMAVSMVLGACSYQKDEPKAKGTSGKSGAKQVLNLIETQEIPTMDPALSADSLSAEVMNNTMEGLYRLG
KGDKLVPGIATEFKKSDDGKKYTFTLRKDAKWSNGDLVTAKDFEYAWKRAINPDTAAKSAYMMYDIKNAEKINKKEMAPD
QLGVKAINDYTLEVELEHAVPYFVDLLIYPLFYPVNEKYVTEQGDKFGLEANTTLYNGPFVLSEWKHERSFQMKKNPSYW
EHKEVKLEEVNFNIVKDTATPINLYETKAVDRAILLAEFIDKYKGKPDFKTFEETTVFFLRLNQKDPALANKNIRKAISL
AFDRKPFVETILNNGSTAATGLIPGNFMFGPNKKDFRVENGDIVKPNIKEAQKYWEAGKKELGKNEIELELLNEDVELSK
KTGEYLKGELEKNLPGLTLKIKQQPFAQKLKLEGAGDYVMSFTGWSADFPDPISYLDMFVTGGTQNKMGYSNPKYDEIIM
KAKKNGNDANARWKSLLTAEKMLLEDAAIVPVYQRGRAYLQRETVKDLYFHKYGGDLSFKWTSVE

Sequences:

>Translated_545_residues
MRKKLPIFVASTMAVSMVLGACSYQKDEPKAKGTSGKSGAKQVLNLIETQEIPTMDPALSADSLSAEVMNNTMEGLYRLG
KGDKLVPGIATEFKKSDDGKKYTFTLRKDAKWSNGDLVTAKDFEYAWKRAINPDTAAKSAYMMYDIKNAEKINKKEMAPD
QLGVKAINDYTLEVELEHAVPYFVDLLIYPLFYPVNEKYVTEQGDKFGLEANTTLYNGPFVLSEWKHERSFQMKKNPSYW
EHKEVKLEEVNFNIVKDTATPINLYETKAVDRAILLAEFIDKYKGKPDFKTFEETTVFFLRLNQKDPALANKNIRKAISL
AFDRKPFVETILNNGSTAATGLIPGNFMFGPNKKDFRVENGDIVKPNIKEAQKYWEAGKKELGKNEIELELLNEDVELSK
KTGEYLKGELEKNLPGLTLKIKQQPFAQKLKLEGAGDYVMSFTGWSADFPDPISYLDMFVTGGTQNKMGYSNPKYDEIIM
KAKKNGNDANARWKSLLTAEKMLLEDAAIVPVYQRGRAYLQRETVKDLYFHKYGGDLSFKWTSVE
>Mature_545_residues
MRKKLPIFVASTMAVSMVLGACSYQKDEPKAKGTSGKSGAKQVLNLIETQEIPTMDPALSADSLSAEVMNNTMEGLYRLG
KGDKLVPGIATEFKKSDDGKKYTFTLRKDAKWSNGDLVTAKDFEYAWKRAINPDTAAKSAYMMYDIKNAEKINKKEMAPD
QLGVKAINDYTLEVELEHAVPYFVDLLIYPLFYPVNEKYVTEQGDKFGLEANTTLYNGPFVLSEWKHERSFQMKKNPSYW
EHKEVKLEEVNFNIVKDTATPINLYETKAVDRAILLAEFIDKYKGKPDFKTFEETTVFFLRLNQKDPALANKNIRKAISL
AFDRKPFVETILNNGSTAATGLIPGNFMFGPNKKDFRVENGDIVKPNIKEAQKYWEAGKKELGKNEIELELLNEDVELSK
KTGEYLKGELEKNLPGLTLKIKQQPFAQKLKLEGAGDYVMSFTGWSADFPDPISYLDMFVTGGTQNKMGYSNPKYDEIIM
KAKKNGNDANARWKSLLTAEKMLLEDAAIVPVYQRGRAYLQRETVKDLYFHKYGGDLSFKWTSVE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=530, Percent_Identity=28.1132075471698, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1789397, Length=506, Percent_Identity=27.8656126482213, Blast_Score=188, Evalue=9e-49,
Organism=Escherichia coli, GI87081878, Length=492, Percent_Identity=28.0487804878049, Blast_Score=181, Evalue=9e-47,
Organism=Escherichia coli, GI1787762, Length=510, Percent_Identity=23.1372549019608, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1787052, Length=476, Percent_Identity=22.4789915966387, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1789887, Length=356, Percent_Identity=23.5955056179775, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61802; Mature: 61802

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKKLPIFVASTMAVSMVLGACSYQKDEPKAKGTSGKSGAKQVLNLIETQEIPTMDPALS
CCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADSLSAEVMNNTMEGLYRLGKGDKLVPGIATEFKKSDDGKKYTFTLRKDAKWSNGDLVTA
CHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
KDFEYAWKRAINPDTAAKSAYMMYDIKNAEKINKKEMAPDQLGVKAINDYTLEVELEHAV
CCHHHHHHHCCCCCHHHCCEEEEEEECCHHHCCHHHCCCHHHCCEEECCEEEEEEECCCC
PYFVDLLIYPLFYPVNEKYVTEQGDKFGLEANTTLYNGPFVLSEWKHERSFQMKKNPSYW
HHHHHHHHHHHHCCCCCCEECCCCCEECCEECCEEECCCEEEECCCCCCCCCCCCCCCCC
EHKEVKLEEVNFNIVKDTATPINLYETKAVDRAILLAEFIDKYKGKPDFKTFEETTVFFL
CCCCEEEEECCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
RLNQKDPALANKNIRKAISLAFDRKPFVETILNNGSTAATGLIPGNFMFGPNKKDFRVEN
EECCCCCCHHCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCEEECCCCCCEEECC
GDIVKPNIKEAQKYWEAGKKELGKNEIELELLNEDVELSKKTGEYLKGELEKNLPGLTLK
CCEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEE
IKQQPFAQKLKLEGAGDYVMSFTGWSADFPDPISYLDMFVTGGTQNKMGYSNPKYDEIIM
ECCCCCHHHEEECCCCCEEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHH
KAKKNGNDANARWKSLLTAEKMLLEDAAIVPVYQRGRAYLQRETVKDLYFHKYGGDLSFK
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
WTSVE
EECCC
>Mature Secondary Structure
MRKKLPIFVASTMAVSMVLGACSYQKDEPKAKGTSGKSGAKQVLNLIETQEIPTMDPALS
CCCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADSLSAEVMNNTMEGLYRLGKGDKLVPGIATEFKKSDDGKKYTFTLRKDAKWSNGDLVTA
CHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
KDFEYAWKRAINPDTAAKSAYMMYDIKNAEKINKKEMAPDQLGVKAINDYTLEVELEHAV
CCHHHHHHHCCCCCHHHCCEEEEEEECCHHHCCHHHCCCHHHCCEEECCEEEEEEECCCC
PYFVDLLIYPLFYPVNEKYVTEQGDKFGLEANTTLYNGPFVLSEWKHERSFQMKKNPSYW
HHHHHHHHHHHHCCCCCCEECCCCCEECCEECCEEECCCEEEECCCCCCCCCCCCCCCCC
EHKEVKLEEVNFNIVKDTATPINLYETKAVDRAILLAEFIDKYKGKPDFKTFEETTVFFL
CCCCEEEEECCEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEE
RLNQKDPALANKNIRKAISLAFDRKPFVETILNNGSTAATGLIPGNFMFGPNKKDFRVEN
EECCCCCCHHCHHHHHHHHHHCCCCHHHHHHHCCCCCEEEECCCCCEEECCCCCCEEECC
GDIVKPNIKEAQKYWEAGKKELGKNEIELELLNEDVELSKKTGEYLKGELEKNLPGLTLK
CCEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEE
IKQQPFAQKLKLEGAGDYVMSFTGWSADFPDPISYLDMFVTGGTQNKMGYSNPKYDEIIM
ECCCCCHHHEEECCCCCEEEEEECCCCCCCCHHHHHHHHEECCCCCCCCCCCCCHHHHHH
KAKKNGNDANARWKSLLTAEKMLLEDAAIVPVYQRGRAYLQRETVKDLYFHKYGGDLSFK
HHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEE
WTSVE
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]