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The map label for this gene is fabF [H]

Identifier: 152974704

GI number: 152974704

Start: 1007047

End: 1008285

Strand: Direct

Name: fabF [H]

Synonym: Bcer98_0891

Alternate gene names: 152974704

Gene position: 1007047-1008285 (Clockwise)

Preceding gene: 152974703

Following gene: 152974705

Centisome position: 24.64

GC content: 42.45

Gene sequence:

>1239_bases
ATGGAAAAAAAGAGGGTCGTAATTACTGGATTAGGAGCTGTAACGCCAGTTGGAACAGATGTTGAAACTGCTTGGGAAAA
TATTAAAAATGGTGTATCTGGAATCGGACGACTAACACGATTAGATCCAGAGCAATTTCCAGCAAAAGTAGCAGCAGAAA
TTAACGACTTTGAAGTCGAAAAATATATTGAGAAAAAAGAAGCGCGTCGCATGGATCGATTTACACAATATGCGGTAGCG
GCAGCAAAAATGGCAGTTGCTGATGCGAAATTAGAAATTACAGAAGAAAATGCACCGCGCATTGGTGTATGGATTGGTTC
TGGAATTGGGGGTATGGAAACATACGAAGAACAATTCAAAATCTTCATGGAAAAAGGCGCGCGCCGCGTAAGTCCGTTCT
TCGTACCGATGATGATTCCTGATATGGCAGCTGGTCAAGTATCGATTGCGACAGGTGCAAAAGGAATTAACACTTGCTCC
GTAACAGCTTGTGCATCAGGAGCAAACTCAATTGGAGATGCTTTTAAAGTCATTCAGCGCGGGGATGCTGATGCGATGAT
TGCAGGGGGGGCAGAAGCGCCTCTTACGCATATGGCATTTGCAGGATTTAGTTCAGCGAAAGCATTAACATTTAATGAAG
ATCCAGCGACTGCATGTCGTCCATTTGATAAAAATCGCAGCGGTTTTGTCATGGGAGAAGGTGCAGGTATTCTTATTCTT
GAAGAATTAGAACATGCATTAGCACGCGGTGCTCATATTTATGCAGAAGTTGCTGGTTATGGTGCAACAGGAGATGCATT
CCATATTACACTACCTGCGCCAGGTGGTGAAGGCGGCGTGCGCGCAATGCGTCAAGCTTTAGCTGATGCAGGTCTTAAAC
CAGAAGATATTGACTACATTAATGCGCATGGTACAAGTACAGATGCCAATGAAAAATATGAAACAATGGCGATTAAAGAA
GCATTTGGTGAACATGCATATAAAGTAGCAATTAGTTCCACGAAATCAATGACAGGTCACTTATTAGGAGCAGCTGGTGC
TGTTGAGGCAATTTTCTCTATTAAGTCCATTACAGATGGAGTCATTCCTCCAACAATCAACTATGAAACACCAGATCCAG
AATGTGATTTAGATTACGTACCAAATGAAGCAAGACATCAAGAAGTCCGCGCCGTATTAAGTAACTCATTAGGATTTGGC
GGACATAACGCAGCGCTAGTATTTAAGGCATATAAATAA

Upstream 100 bases:

>100_bases
TCTTATCATACTCGTTGGCTTTGGTGGTGGATTAACATGGGGGGCAGTTGCTCTTCGTTGGGGTAAATAAGGACTGAGAG
AAAAAAGGAGTGTATTTTGT

Downstream 100 bases:

>100_bases
TGAGAACGAAAGAGGCTGTCCAAAGTAGGGCGGCCTCTATTTATTTTTGTCCTTAATGTGCCCTCTTCTTTTTCTGCATA
TATATAAGAAAAGGAGGTAG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MEKKRVVITGLGAVTPVGTDVETAWENIKNGVSGIGRLTRLDPEQFPAKVAAEINDFEVEKYIEKKEARRMDRFTQYAVA
AAKMAVADAKLEITEENAPRIGVWIGSGIGGMETYEEQFKIFMEKGARRVSPFFVPMMIPDMAAGQVSIATGAKGINTCS
VTACASGANSIGDAFKVIQRGDADAMIAGGAEAPLTHMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGAGILIL
EELEHALARGAHIYAEVAGYGATGDAFHITLPAPGGEGGVRAMRQALADAGLKPEDIDYINAHGTSTDANEKYETMAIKE
AFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNEARHQEVRAVLSNSLGFG
GHNAALVFKAYK

Sequences:

>Translated_412_residues
MEKKRVVITGLGAVTPVGTDVETAWENIKNGVSGIGRLTRLDPEQFPAKVAAEINDFEVEKYIEKKEARRMDRFTQYAVA
AAKMAVADAKLEITEENAPRIGVWIGSGIGGMETYEEQFKIFMEKGARRVSPFFVPMMIPDMAAGQVSIATGAKGINTCS
VTACASGANSIGDAFKVIQRGDADAMIAGGAEAPLTHMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGAGILIL
EELEHALARGAHIYAEVAGYGATGDAFHITLPAPGGEGGVRAMRQALADAGLKPEDIDYINAHGTSTDANEKYETMAIKE
AFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNEARHQEVRAVLSNSLGFG
GHNAALVFKAYK
>Mature_412_residues
MEKKRVVITGLGAVTPVGTDVETAWENIKNGVSGIGRLTRLDPEQFPAKVAAEINDFEVEKYIEKKEARRMDRFTQYAVA
AAKMAVADAKLEITEENAPRIGVWIGSGIGGMETYEEQFKIFMEKGARRVSPFFVPMMIPDMAAGQVSIATGAKGINTCS
VTACASGANSIGDAFKVIQRGDADAMIAGGAEAPLTHMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGAGILIL
EELEHALARGAHIYAEVAGYGATGDAFHITLPAPGGEGGVRAMRQALADAGLKPEDIDYINAHGTSTDANEKYETMAIKE
AFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDGVIPPTINYETPDPECDLDYVPNEARHQEVRAVLSNSLGFG
GHNAALVFKAYK

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=415, Percent_Identity=47.4698795180723, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI223972627, Length=166, Percent_Identity=51.2048192771084, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI41872631, Length=432, Percent_Identity=25, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=51.5815085158151, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1788663, Length=418, Percent_Identity=38.2775119617225, Blast_Score=248, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=37.378640776699, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=255, Percent_Identity=43.1372549019608, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17550940, Length=417, Percent_Identity=23.7410071942446, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=375, Percent_Identity=26.4, Blast_Score=108, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=38.7527839643653, Blast_Score=272, Evalue=7e-74,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=44.2583732057416, Blast_Score=350, Evalue=7e-97,
Organism=Drosophila melanogaster, GI221330659, Length=430, Percent_Identity=25.5813953488372, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920632, Length=430, Percent_Identity=25.5813953488372, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24581345, Length=433, Percent_Identity=23.7875288683603, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43719; Mature: 43719

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKRVVITGLGAVTPVGTDVETAWENIKNGVSGIGRLTRLDPEQFPAKVAAEINDFEVE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHCCCHHHHH
KYIEKKEARRMDRFTQYAVAAAKMAVADAKLEITEENAPRIGVWIGSGIGGMETYEEQFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHH
IFMEKGARRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTACASGANSIGDAFKVIQR
HHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEEEEHHCCCHHHHHHHHHHHC
GDADAMIAGGAEAPLTHMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGAGILIL
CCCCEEEECCCCCCHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCCEEEECCCCEEEH
EELEHALARGAHIYAEVAGYGATGDAFHITLPAPGGEGGVRAMRQALADAGLKPEDIDYI
HHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEE
NAHGTSTDANEKYETMAIKEAFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDG
ECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VIPPTINYETPDPECDLDYVPNEARHQEVRAVLSNSLGFGGHNAALVFKAYK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MEKKRVVITGLGAVTPVGTDVETAWENIKNGVSGIGRLTRLDPEQFPAKVAAEINDFEVE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHHHCCCHHHHH
KYIEKKEARRMDRFTQYAVAAAKMAVADAKLEITEENAPRIGVWIGSGIGGMETYEEQFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCHHHHHHHHH
IFMEKGARRVSPFFVPMMIPDMAAGQVSIATGAKGINTCSVTACASGANSIGDAFKVIQR
HHHHHCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEEEEHHCCCHHHHHHHHHHHC
GDADAMIAGGAEAPLTHMAFAGFSSAKALTFNEDPATACRPFDKNRSGFVMGEGAGILIL
CCCCEEEECCCCCCHHHHHHCCCCCCEEEEECCCCCHHCCCCCCCCCCEEEECCCCEEEH
EELEHALARGAHIYAEVAGYGATGDAFHITLPAPGGEGGVRAMRQALADAGLKPEDIDYI
HHHHHHHHCCCEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCEE
NAHGTSTDANEKYETMAIKEAFGEHAYKVAISSTKSMTGHLLGAAGAVEAIFSIKSITDG
ECCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
VIPPTINYETPDPECDLDYVPNEARHQEVRAVLSNSLGFGGHNAALVFKAYK
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]