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The map label for this gene is yisK [H]

Identifier: 152974681

GI number: 152974681

Start: 985169

End: 986077

Strand: Direct

Name: yisK [H]

Synonym: Bcer98_0868

Alternate gene names: 152974681

Gene position: 985169-986077 (Clockwise)

Preceding gene: 152974673

Following gene: 152974683

Centisome position: 24.1

GC content: 38.72

Gene sequence:

>909_bases
GTGGAAATTTTGCGTTTGGTGACGGTGAAGAAAGATGAGAAAGTGTTTATTGGTGTTGTAGACGAAGAGGAAAAGAAAGT
GCTGCATTTAAGAGAAGCACAAAAACAAAAGGGTGAAAAAGTTACGCTTCCAATTACCATGTTAGAATGTATTGAAAGAG
GAAGCGAATGTATGGAAAAGGTGCGTGAAATTGTAAATTGGGCAAACGAAAATAAACTAGCAGCTTACTATTCCTTACAA
GAAGTGAAACTATTAGCTCCTATACCGAGACCACGGAAAAATATTCTTTGTGTTGGGAAGAATTACCGTGAACATGCGAT
CGAAATGGGAGGAGAGGAATCTATCCCAAACAATATAATGATTTTTACGAAGGCACCTACGACTGTAATAGGGAATGGTG
AAAAAATTAATAGCCATTCGCACGCGACGAGTGAATTGGATTATGAAGGGGAACTCGCGATTGTCATTGGAAAGCGAGGC
AAACAAATTCCAAAAGATAAAGCAATGGAATATATATTTGGTTATACGATTGTAAATGATATAACAGCGCGGGATATTCA
AAGGAAGCATAAACAATTTTTCTTGGGGAAAAGTTTTGATACATTTTGCCCGATGGGGCCGTATTTAGTGCATACATCAG
GGATTCAGTCTCCCAGTCAATTACACATTGAAACAAAGGTAAACGGGGAAGTTAGACAAACTTCTAATACGGAAAATATG
ATATTTCCGATAGAAGAAATTATTTCTACTGTGAGTAAAGGAATGACGCTTGAGCCTGGAGATATCATTGCAACCGGGAC
GCCCGCGGGCGTTGGAAAAGGCTTTAATCCACCAAAATTTTTGCGTGCTGGTGATGAAGTGATCGTAACAGTCGAGGGCA
TTGGAACATTAAAAAATATCGTAAAGTAA

Upstream 100 bases:

>100_bases
ATTGTAAAATAAAGAATATTGTAAAAAATAAGGAAGGATAGAAGGTTTTTTTCTAAGGAATGCGAATACAATTATAGTGT
ATGGAGTTTTAGGATGGAGA

Downstream 100 bases:

>100_bases
AAGACTACCTTTTTGAAAAGAGGTAGTCTTTCTTTCAATCTTTTAGTTCAAATGTCATTTCAAATCGTAAGAGAGGCTGT
CCGAAAAAAGAGGATCGCCT

Product: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MEILRLVTVKKDEKVFIGVVDEEEKKVLHLREAQKQKGEKVTLPITMLECIERGSECMEKVREIVNWANENKLAAYYSLQ
EVKLLAPIPRPRKNILCVGKNYREHAIEMGGEESIPNNIMIFTKAPTTVIGNGEKINSHSHATSELDYEGELAIVIGKRG
KQIPKDKAMEYIFGYTIVNDITARDIQRKHKQFFLGKSFDTFCPMGPYLVHTSGIQSPSQLHIETKVNGEVRQTSNTENM
IFPIEEIISTVSKGMTLEPGDIIATGTPAGVGKGFNPPKFLRAGDEVIVTVEGIGTLKNIVK

Sequences:

>Translated_302_residues
MEILRLVTVKKDEKVFIGVVDEEEKKVLHLREAQKQKGEKVTLPITMLECIERGSECMEKVREIVNWANENKLAAYYSLQ
EVKLLAPIPRPRKNILCVGKNYREHAIEMGGEESIPNNIMIFTKAPTTVIGNGEKINSHSHATSELDYEGELAIVIGKRG
KQIPKDKAMEYIFGYTIVNDITARDIQRKHKQFFLGKSFDTFCPMGPYLVHTSGIQSPSQLHIETKVNGEVRQTSNTENM
IFPIEEIISTVSKGMTLEPGDIIATGTPAGVGKGFNPPKFLRAGDEVIVTVEGIGTLKNIVK
>Mature_302_residues
MEILRLVTVKKDEKVFIGVVDEEEKKVLHLREAQKQKGEKVTLPITMLECIERGSECMEKVREIVNWANENKLAAYYSLQ
EVKLLAPIPRPRKNILCVGKNYREHAIEMGGEESIPNNIMIFTKAPTTVIGNGEKINSHSHATSELDYEGELAIVIGKRG
KQIPKDKAMEYIFGYTIVNDITARDIQRKHKQFFLGKSFDTFCPMGPYLVHTSGIQSPSQLHIETKVNGEVRQTSNTENM
IFPIEEIISTVSKGMTLEPGDIIATGTPAGVGKGFNPPKFLRAGDEVIVTVEGIGTLKNIVK

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=265, Percent_Identity=41.5094339622642, Blast_Score=197, Evalue=8e-51,
Organism=Homo sapiens, GI40786394, Length=265, Percent_Identity=41.1320754716981, Blast_Score=195, Evalue=4e-50,
Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=43.4782608695652, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI13654274, Length=209, Percent_Identity=39.7129186602871, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI66348062, Length=206, Percent_Identity=40.2912621359223, Blast_Score=139, Evalue=5e-33,
Organism=Escherichia coli, GI1787428, Length=207, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17557057, Length=183, Percent_Identity=42.0765027322404, Blast_Score=137, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=229, Percent_Identity=29.2576419213974, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28572127, Length=221, Percent_Identity=42.9864253393665, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24663695, Length=221, Percent_Identity=39.3665158371041, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI28571789, Length=199, Percent_Identity=32.1608040201005, Blast_Score=98, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 33709; Mature: 33709

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEILRLVTVKKDEKVFIGVVDEEEKKVLHLREAQKQKGEKVTLPITMLECIERGSECMEK
CCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
VREIVNWANENKLAAYYSLQEVKLLAPIPRPRKNILCVGKNYREHAIEMGGEESIPNNIM
HHHHHHHCCCCCEEEEEEHHHHHEECCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCEE
IFTKAPTTVIGNGEKINSHSHATSELDYEGELAIVIGKRGKQIPKDKAMEYIFGYTIVND
EEECCCCEEECCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
ITARDIQRKHKQFFLGKSFDTFCPMGPYLVHTSGIQSPSQLHIETKVNGEVRQTSNTENM
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCCE
IFPIEEIISTVSKGMTLEPGDIIATGTPAGVGKGFNPPKFLRAGDEVIVTVEGIGTLKNI
EECHHHHHHHHHCCCEECCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHH
VK
CC
>Mature Secondary Structure
MEILRLVTVKKDEKVFIGVVDEEEKKVLHLREAQKQKGEKVTLPITMLECIERGSECMEK
CCCEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHH
VREIVNWANENKLAAYYSLQEVKLLAPIPRPRKNILCVGKNYREHAIEMGGEESIPNNIM
HHHHHHHCCCCCEEEEEEHHHHHEECCCCCCCCCEEEECCCHHHHHHHCCCCCCCCCCEE
IFTKAPTTVIGNGEKINSHSHATSELDYEGELAIVIGKRGKQIPKDKAMEYIFGYTIVND
EEECCCCEEECCCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHH
ITARDIQRKHKQFFLGKSFDTFCPMGPYLVHTSGIQSPSQLHIETKVNGEVRQTSNTENM
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCCE
IFPIEEIISTVSKGMTLEPGDIIATGTPAGVGKGFNPPKFLRAGDEVIVTVEGIGTLKNI
EECHHHHHHHHHCCCEECCCCEEEECCCCCCCCCCCCHHHHCCCCEEEEEEECCHHHHHH
VK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377 [H]