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The map label for this gene is comK [H]

Identifier: 152974669

GI number: 152974669

Start: 973099

End: 973689

Strand: Direct

Name: comK [H]

Synonym: Bcer98_0856

Alternate gene names: 152974669

Gene position: 973099-973689 (Clockwise)

Preceding gene: 152974668

Following gene: 152974670

Centisome position: 23.81

GC content: 36.21

Gene sequence:

>591_bases
ATGGATGGTAGAGCTGAGCGCTATGTTGAAAATTACGTAATAAATAAAAAAACTATGGCTTTACTGCCTGTTATTTTAGG
GGAAAAAAATGTAATAACGAGAGTAATTGAAGTGGAAGACTCTTTTTTTATGTTCCAAAAGCCGCTTGATATTGTAGAAC
GAAGCTGTCGTAAGCATGGATCGAGTTTTTTAGGGAGGAAAGAAGGAACCAAAGAGTTAACACGTATTACTCATAAAGCA
CCTATCGCAATTAGTCCCACCGATCAACTTTATTTCTTTCCCACGTATTCCTATTCAAGAAAAGAATGTGCATGGCTCTC
TCATTTTCATATTGCAAGCAATAAAGAGTTAGCAGACGGCAATCTTATTATTCGGTTCATTAATGGGTTTGCAGTGAAAT
TAGAGATGTCAAAGAGTAGTTTTGAGAATCAACAAAACCGTACAGCAAAGCTGAGAACAGAATATGAAGATCGAAAAGAT
AAACAAGGAAACTTGCAGTTTAAGCCAGTTGCAAAAGAAGCGATATCAACGTTAAGACCAGCGTATGAAAAAGTCTACCT
TGTAAAGGAAGAAGATATAGAAGGAGAATGA

Upstream 100 bases:

>100_bases
GTAAAAAAATTGAAAATTTTAATTATTTTACAAAAGGTGTGATACAATTATTTGTGCAGCTGCTAATATAAATGAATTTT
ATAGAAGGAGTGAACACACC

Downstream 100 bases:

>100_bases
TTAATAAATCAGGTAAAATGCTCATATAATAAAAATGAAAAGAAACCAGATATGATGAAGTAACTGGTTTCTTTTTTGTT
ACATGGAAACATGAAAGGTG

Product: ComK family protein

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MDGRAERYVENYVINKKTMALLPVILGEKNVITRVIEVEDSFFMFQKPLDIVERSCRKHGSSFLGRKEGTKELTRITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFHIASNKELADGNLIIRFINGFAVKLEMSKSSFENQQNRTAKLRTEYEDRKD
KQGNLQFKPVAKEAISTLRPAYEKVYLVKEEDIEGE

Sequences:

>Translated_196_residues
MDGRAERYVENYVINKKTMALLPVILGEKNVITRVIEVEDSFFMFQKPLDIVERSCRKHGSSFLGRKEGTKELTRITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFHIASNKELADGNLIIRFINGFAVKLEMSKSSFENQQNRTAKLRTEYEDRKD
KQGNLQFKPVAKEAISTLRPAYEKVYLVKEEDIEGE
>Mature_196_residues
MDGRAERYVENYVINKKTMALLPVILGEKNVITRVIEVEDSFFMFQKPLDIVERSCRKHGSSFLGRKEGTKELTRITHKA
PIAISPTDQLYFFPTYSYSRKECAWLSHFHIASNKELADGNLIIRFINGFAVKLEMSKSSFENQQNRTAKLRTEYEDRKD
KQGNLQFKPVAKEAISTLRPAYEKVYLVKEEDIEGE

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22734; Mature: 22734

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGRAERYVENYVINKKTMALLPVILGEKNVITRVIEVEDSFFMFQKPLDIVERSCRKHG
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEEEECCCHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTRITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFHIASNKELADG
HHHHCCCCCHHHHHHHHHCCCEEECCCCCEEEEECCCCCCHHHHHHHEEEECCCCEECCC
NLIIRFINGFAVKLEMSKSSFENQQNRTAKLRTEYEDRKDKQGNLQFKPVAKEAISTLRP
CEEEEEECCEEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCH
AYEKVYLVKEEDIEGE
HHHEEEEEECCCCCCC
>Mature Secondary Structure
MDGRAERYVENYVINKKTMALLPVILGEKNVITRVIEVEDSFFMFQKPLDIVERSCRKHG
CCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEEEECCCHHHHHCCHHHHHHHHHHHC
SSFLGRKEGTKELTRITHKAPIAISPTDQLYFFPTYSYSRKECAWLSHFHIASNKELADG
HHHHCCCCCHHHHHHHHHCCCEEECCCCCEEEEECCCCCCHHHHHHHEEEECCCCEECCC
NLIIRFINGFAVKLEMSKSSFENQQNRTAKLRTEYEDRKDKQGNLQFKPVAKEAISTLRP
CEEEEEECCEEEEEEECHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECHHHHHHHHHHCH
AYEKVYLVKEEDIEGE
HHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]