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The map label for this gene is yhjB [H]

Identifier: 152974422

GI number: 152974422

Start: 676590

End: 678062

Strand: Direct

Name: yhjB [H]

Synonym: Bcer98_0596

Alternate gene names: 152974422

Gene position: 676590-678062 (Clockwise)

Preceding gene: 152974421

Following gene: 152974423

Centisome position: 16.55

GC content: 37.14

Gene sequence:

>1473_bases
ATGATAGCACTTATTATCATTGTTGTATTTCTATGTTTGGCATTATTTTTAGGAGTTCGTGCAAGAAGTGGAAAAGACAT
GAATTTGGAACAATGGTCGGTTGGGGGAAGGGGATTTGGAACAGTCTTTGTCTTTCTTCTTATGGCAGGAGAAATATATA
CGACGTTTACTTTTCTGGGAGGAAGTGGATGGGCATATAGCAAAGGTGCACCTACATTTTATATTTTAGGATACAGTGCA
TTAGCATATATTTTATCTTACTTTCTCTTACCTCCAGTTTGGAAGTATGCCAAAGAGCATAGATTGATTTCGCAACCAGA
TTTCTTTACCAAAAAATATAATAGTAAAGCGTTAGGGATTATTGTATCGATCATCGGTGTCATTTCAATTATTCCATATC
TTGTACTGCAGTTAAAAGGGTTGGGGATTATTGTTTCTGAAGCTTCTTATGGAAAAGTATCACCAGTTCTTGCTGTTTGG
ATTGGCGGAATAACAATTACAATATATGTGATGATTTCTGGTATACATGGTTCCGCTTGGACAGCTGCATTAAAAGATAT
GATGATCCTATTTATCGTTATGGTTTTAGGTATTTATTTACCCTATCATTATTACGGAGGGTTTCAGCCGATGTTTGAAG
CGGTAGAAGCTGCAAAACCAGGATTTTTATCTTTACCTGAACAAGGAATGAGTGTCTCATGGTTTGTTTCTACTATTATA
TTAACAGCGCTAGGGTTTTATATGTGGCCCCATACATTTGCTGCCGCTTTTTCAGCAAAGAGTGAAAAGGTATTTCGAAA
AAACGCCACTATTATGCCATTATACTCTTTCGTATTACTCTTTGTATTTTTTGCAGGATTTGCGGCTATCTTACAAGTAC
CTAGATTACAGGGGGCAGATGCAGACTTGTCTTTATTCCGCCTTGCTATTCAAACATTTGATCCGTGGTTTATTGGGATC
ATTGGAAGTGCTGGAGTACTAACTGCATTAGTTCCGGGATCTATGCTTCTTATGGCTGCATCTACTTTGTTAGCAAAAAA
TATTTATCAAGTGCTCGCGCCATCCGTATCAGATCAGCAAGTGGCACGAGTAGCCAAGCTATTTGTGCCTATTGTGACGA
TTGTATCTGTTTTCTTTACCTTCAAAGGAGGAGAAACAATTGGAGCTCTGCTTTTAATGGGATACAGCATTGTGACGCAA
CTTTTTCCGGCGCTTGTATGCAGTTTATTTCCACGTCAATTTGTAACAAAACAAGGTGCTATCTCTGGAATGATAGTTGG
ATTATTCATGGTGGCTTATATTACATTATCTGGATCGACTCTCTCTACTATATTTCCAATTTTTCCGCAATATATGAAAG
ATTTAAATGTAGGGATTGTTGCATTAGGAATCAACATCATTGTTATGTTAGCAGTGAGTATCATGACTAGAAAAATTGAA
GTACAGCATACTTCTACTATGTTAGATCGATAA

Upstream 100 bases:

>100_bases
TGCCATTTTTATTATTTTGGATTTTATTATCTGTGTTCATTACCTCCTTTTGTATGTGGATTGTATATTGGCTAGATCCT
GCTAACAAGGAGGAGATGAA

Downstream 100 bases:

>100_bases
AGTGAAACTTAAATCATTTTCTACAAATTATGAGCCGCCACCAATCGGGCTATTACACCTCTAAAATAGCGGGATAAAAA
AATGTTATCTTTCCTTAGGG

Product: Na+ symporter

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MIALIIIVVFLCLALFLGVRARSGKDMNLEQWSVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYSKGAPTFYILGYSA
LAYILSYFLLPPVWKYAKEHRLISQPDFFTKKYNSKALGIIVSIIGVISIIPYLVLQLKGLGIIVSEASYGKVSPVLAVW
IGGITITIYVMISGIHGSAWTAALKDMMILFIVMVLGIYLPYHYYGGFQPMFEAVEAAKPGFLSLPEQGMSVSWFVSTII
LTALGFYMWPHTFAAAFSAKSEKVFRKNATIMPLYSFVLLFVFFAGFAAILQVPRLQGADADLSLFRLAIQTFDPWFIGI
IGSAGVLTALVPGSMLLMAASTLLAKNIYQVLAPSVSDQQVARVAKLFVPIVTIVSVFFTFKGGETIGALLLMGYSIVTQ
LFPALVCSLFPRQFVTKQGAISGMIVGLFMVAYITLSGSTLSTIFPIFPQYMKDLNVGIVALGINIIVMLAVSIMTRKIE
VQHTSTMLDR

Sequences:

>Translated_490_residues
MIALIIIVVFLCLALFLGVRARSGKDMNLEQWSVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYSKGAPTFYILGYSA
LAYILSYFLLPPVWKYAKEHRLISQPDFFTKKYNSKALGIIVSIIGVISIIPYLVLQLKGLGIIVSEASYGKVSPVLAVW
IGGITITIYVMISGIHGSAWTAALKDMMILFIVMVLGIYLPYHYYGGFQPMFEAVEAAKPGFLSLPEQGMSVSWFVSTII
LTALGFYMWPHTFAAAFSAKSEKVFRKNATIMPLYSFVLLFVFFAGFAAILQVPRLQGADADLSLFRLAIQTFDPWFIGI
IGSAGVLTALVPGSMLLMAASTLLAKNIYQVLAPSVSDQQVARVAKLFVPIVTIVSVFFTFKGGETIGALLLMGYSIVTQ
LFPALVCSLFPRQFVTKQGAISGMIVGLFMVAYITLSGSTLSTIFPIFPQYMKDLNVGIVALGINIIVMLAVSIMTRKIE
VQHTSTMLDR
>Mature_490_residues
MIALIIIVVFLCLALFLGVRARSGKDMNLEQWSVGGRGFGTVFVFLLMAGEIYTTFTFLGGSGWAYSKGAPTFYILGYSA
LAYILSYFLLPPVWKYAKEHRLISQPDFFTKKYNSKALGIIVSIIGVISIIPYLVLQLKGLGIIVSEASYGKVSPVLAVW
IGGITITIYVMISGIHGSAWTAALKDMMILFIVMVLGIYLPYHYYGGFQPMFEAVEAAKPGFLSLPEQGMSVSWFVSTII
LTALGFYMWPHTFAAAFSAKSEKVFRKNATIMPLYSFVLLFVFFAGFAAILQVPRLQGADADLSLFRLAIQTFDPWFIGI
IGSAGVLTALVPGSMLLMAASTLLAKNIYQVLAPSVSDQQVARVAKLFVPIVTIVSVFFTFKGGETIGALLLMGYSIVTQ
LFPALVCSLFPRQFVTKQGAISGMIVGLFMVAYITLSGSTLSTIFPIFPQYMKDLNVGIVALGINIIVMLAVSIMTRKIE
VQHTSTMLDR

Specific function: Catalyzes The Sodium-Dependent Uptake Of Extracellular Pantothenate. [C]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI87082237, Length=430, Percent_Identity=22.5581395348837, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53542; Mature: 53542

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALIIIVVFLCLALFLGVRARSGKDMNLEQWSVGGRGFGTVFVFLLMAGEIYTTFTFLG
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GSGWAYSKGAPTFYILGYSALAYILSYFLLPPVWKYAKEHRLISQPDFFTKKYNSKALGI
CCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHH
IVSIIGVISIIPYLVLQLKGLGIIVSEASYGKVSPVLAVWIGGITITIYVMISGIHGSAW
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
TAALKDMMILFIVMVLGIYLPYHYYGGFQPMFEAVEAAKPGFLSLPEQGMSVSWFVSTII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LTALGFYMWPHTFAAAFSAKSEKVFRKNATIMPLYSFVLLFVFFAGFAAILQVPRLQGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADLSLFRLAIQTFDPWFIGIIGSAGVLTALVPGSMLLMAASTLLAKNIYQVLAPSVSDQQ
CHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VARVAKLFVPIVTIVSVFFTFKGGETIGALLLMGYSIVTQLFPALVCSLFPRQFVTKQGA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISGMIVGLFMVAYITLSGSTLSTIFPIFPQYMKDLNVGIVALGINIIVMLAVSIMTRKIE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VQHTSTMLDR
HHHHHHHHCC
>Mature Secondary Structure
MIALIIIVVFLCLALFLGVRARSGKDMNLEQWSVGGRGFGTVFVFLLMAGEIYTTFTFLG
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEC
GSGWAYSKGAPTFYILGYSALAYILSYFLLPPVWKYAKEHRLISQPDFFTKKYNSKALGI
CCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHH
IVSIIGVISIIPYLVLQLKGLGIIVSEASYGKVSPVLAVWIGGITITIYVMISGIHGSAW
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
TAALKDMMILFIVMVLGIYLPYHYYGGFQPMFEAVEAAKPGFLSLPEQGMSVSWFVSTII
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LTALGFYMWPHTFAAAFSAKSEKVFRKNATIMPLYSFVLLFVFFAGFAAILQVPRLQGAD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
ADLSLFRLAIQTFDPWFIGIIGSAGVLTALVPGSMLLMAASTLLAKNIYQVLAPSVSDQQ
CHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VARVAKLFVPIVTIVSVFFTFKGGETIGALLLMGYSIVTQLFPALVCSLFPRQFVTKQGA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ISGMIVGLFMVAYITLSGSTLSTIFPIFPQYMKDLNVGIVALGINIIVMLAVSIMTRKIE
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
VQHTSTMLDR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]