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The map label for this gene is rocE [H]

Identifier: 152974371

GI number: 152974371

Start: 621778

End: 623196

Strand: Direct

Name: rocE [H]

Synonym: Bcer98_0544

Alternate gene names: 152974371

Gene position: 621778-623196 (Clockwise)

Preceding gene: 152974370

Following gene: 152974372

Centisome position: 15.21

GC content: 37.28

Gene sequence:

>1419_bases
ATGCAGCAAACAACGAACGAGAAATTACATCGAACGATGAAGAGTAGACATTTATTTATGATTGCGCTTGGGGGTGTCAT
CGGAACAGGTTTTTTTCTTGGATCAGGGTATACGATTAACCAGGCAGGACCAGGGGGAGCTATTCTTTCTTATTTAGTTG
GTGGATTTATTATGTATTTAACGATGCTTTGTCTCGGTGAACTAACTGTCGCGATGCCAGTTTCTGGATCTTTTCAAAAA
TATGCGACGAAATTTATTGGGCCAGGAACAGGTTTTATGATTGGATGGTTATATTGGCTAGGATGGGCTGTTACAGTTGG
ATTAGAGCTAACATCAATAGGCTTGATGATGAAAAGATGGTTTCCATCTGTAGGTGTTTGGGTATGGTGTTTGATCTTTG
GACTTATTTTATACATTTCGAATGCAATTTCAGCGAAAAGCTATGCTGAATTAGAGTTTTGGTTCTCTAGTATAAAAGTA
ATTACAATTGTTGTATTTGTCGTTTTAGGAGGCTGTGCATTGCTTGGCTTTTTACCGTATGATGGAAAAGCGGCAGCACC
TCTTTTTTCTAACTTTGTAAATGACGGTGGATTGTTTCCAAATGGGGTTGCTGCTGTACTTCTTACAATGATTACAGTTA
ATTTTTCTTTTCAAGGAACAGAACTTATCGGGATAGCAGCTGGAGAAAGTGAACAGCCAGAGAAAACAATTCCTCGTGCC
ATTCGTAACACAGTATGGCGCATCATGTTATTCTTTATTTTAACAATGACGATTTTAGTAGGATTAATTTCATGGAAAGA
AGCAGGGGTTATTGAAAGCCCGTTCGTTGTTGTATTTGATAAAATTGGGATTCCTTATGCAGCCGATATTATGAACTTTG
TCATTATTACAGCGCTATTATCTGTAGCAAATTCTGGATTATACGCAGCGACGCGTATACTATGGTCTCTTGCAAATGAA
GGAATGGCACCGACTTCTTTCAAAAAAGTAAATAAACGTGGTATTCCAATTACAGCGTTAATTGTTACGATTGCTGTAGC
TGGTTTATCTTTACTGACAAGCTTCTTTGCAGAAGATACAGTATACATGTATCTATTGTCTGTAGCAGGATTATCTGCTG
TTGCTAGCTGGGTTATTATTGCGCTATCACAACTTCGTTTTAGAAGTCAGTATGTAAAGGATGGAGGCAAGTTAGAAGAC
TTGAAATATAAGACTCCGCTATATCCAATTGTTCCAATTCTAGCTCTCGTTACAAATAGTATCGTTATCATTAGTTTAGC
GTTTATTCCAGAACAACGGATGGCTTTATATTGCGGTATTCCATTTATCATTTGTTGCTATGTGTATTATTATATAAATA
AGAAGCGGCAAAAAGTGATGAAAGTGGAGATGGATAAAGCGTATGAGACTAACAATTAA

Upstream 100 bases:

>100_bases
GAAAAGTTTTAATTTTATATAGAAATTGTAAACGCTTTCGTGTATATTTTTATTATCAGAAAATTTTCAAAACAGAGGGT
TTTTATAGGGGAGGATTACG

Downstream 100 bases:

>100_bases
GCATGATCATATTCAAGCTGAGTATTCGTATGGACAGTTGTCAATTGGAAAAGAAAATGGGTATTCCCCGTTAGAACTAT
TCATTTCTTCCATTGCAGGA

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPSVGVWVWCLIFGLILYISNAISAKSYAELEFWFSSIKV
ITIVVFVVLGGCALLGFLPYDGKAAAPLFSNFVNDGGLFPNGVAAVLLTMITVNFSFQGTELIGIAAGESEQPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFKKVNKRGIPITALIVTIAVAGLSLLTSFFAEDTVYMYLLSVAGLSAVASWVIIALSQLRFRSQYVKDGGKLED
LKYKTPLYPIVPILALVTNSIVIISLAFIPEQRMALYCGIPFIICCYVYYYINKKRQKVMKVEMDKAYETNN

Sequences:

>Translated_472_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPSVGVWVWCLIFGLILYISNAISAKSYAELEFWFSSIKV
ITIVVFVVLGGCALLGFLPYDGKAAAPLFSNFVNDGGLFPNGVAAVLLTMITVNFSFQGTELIGIAAGESEQPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFKKVNKRGIPITALIVTIAVAGLSLLTSFFAEDTVYMYLLSVAGLSAVASWVIIALSQLRFRSQYVKDGGKLED
LKYKTPLYPIVPILALVTNSIVIISLAFIPEQRMALYCGIPFIICCYVYYYINKKRQKVMKVEMDKAYETNN
>Mature_472_residues
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPSVGVWVWCLIFGLILYISNAISAKSYAELEFWFSSIKV
ITIVVFVVLGGCALLGFLPYDGKAAAPLFSNFVNDGGLFPNGVAAVLLTMITVNFSFQGTELIGIAAGESEQPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFKKVNKRGIPITALIVTIAVAGLSLLTSFFAEDTVYMYLLSVAGLSAVASWVIIALSQLRFRSQYVKDGGKLED
LKYKTPLYPIVPILALVTNSIVIISLAFIPEQRMALYCGIPFIICCYVYYYINKKRQKVMKVEMDKAYETNN

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=351, Percent_Identity=24.5014245014245, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI71999149, Length=349, Percent_Identity=23.2091690544413, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=49.5689655172414, Blast_Score=484, Evalue=1e-138,
Organism=Escherichia coli, GI1788480, Length=481, Percent_Identity=41.995841995842, Blast_Score=374, Evalue=1e-104,
Organism=Escherichia coli, GI1786302, Length=461, Percent_Identity=34.9240780911063, Blast_Score=301, Evalue=7e-83,
Organism=Escherichia coli, GI1786789, Length=436, Percent_Identity=36.697247706422, Blast_Score=291, Evalue=7e-80,
Organism=Escherichia coli, GI1789017, Length=434, Percent_Identity=36.1751152073733, Blast_Score=285, Evalue=4e-78,
Organism=Escherichia coli, GI87081915, Length=406, Percent_Identity=38.1773399014778, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI48994972, Length=465, Percent_Identity=34.1935483870968, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1786602, Length=455, Percent_Identity=34.7252747252747, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1790653, Length=465, Percent_Identity=32.6881720430108, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI87081869, Length=243, Percent_Identity=25.5144032921811, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI2367353, Length=346, Percent_Identity=23.4104046242775, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=442, Percent_Identity=23.9819004524887, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540018, Length=370, Percent_Identity=24.8648648648649, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=442, Percent_Identity=33.2579185520362, Blast_Score=256, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=32.3040380047506, Blast_Score=246, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6324059, Length=427, Percent_Identity=32.7868852459016, Blast_Score=223, Evalue=4e-59,
Organism=Saccharomyces cerevisiae, GI6324553, Length=407, Percent_Identity=32.4324324324324, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6320717, Length=483, Percent_Identity=30.2277432712215, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6322892, Length=494, Percent_Identity=30.7692307692308, Blast_Score=214, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6319824, Length=495, Percent_Identity=29.2929292929293, Blast_Score=210, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6324990, Length=494, Percent_Identity=28.5425101214575, Blast_Score=209, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6319542, Length=416, Percent_Identity=32.2115384615385, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6320251, Length=421, Percent_Identity=31.1163895486936, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6319543, Length=417, Percent_Identity=29.2565947242206, Blast_Score=205, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321629, Length=420, Percent_Identity=28.0952380952381, Blast_Score=203, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6322967, Length=505, Percent_Identity=27.9207920792079, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6321053, Length=417, Percent_Identity=26.8585131894484, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=458, Percent_Identity=29.6943231441048, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=509, Percent_Identity=29.2730844793713, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6319608, Length=438, Percent_Identity=26.4840182648402, Blast_Score=163, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6320364, Length=555, Percent_Identity=23.4234234234234, Blast_Score=112, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24667468, Length=408, Percent_Identity=23.5294117647059, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221512776, Length=435, Percent_Identity=21.8390804597701, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24666159, Length=435, Percent_Identity=21.8390804597701, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51860; Mature: 51860

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPSVGVWVWCLIFGLILYISNAISAKSYAELEFWFSSIKVITIVVFVVLGGCALLGFLPY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGKAAAPLFSNFVNDGGLFPNGVAAVLLTMITVNFSFQGTELIGIAAGESEQPEKTIPRA
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFKKVNKRGIPITALIVTIAVAGLSLLTSFFAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSVAGLSAVASWVIIALSQLRFRSQYVKDGGKLEDLKYKTPLYPIVPILALVTNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVIISLAFIPEQRMALYCGIPFIICCYVYYYINKKRQKVMKVEMDKAYETNN
HHEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQQTTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPSVGVWVWCLIFGLILYISNAISAKSYAELEFWFSSIKVITIVVFVVLGGCALLGFLPY
CCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DGKAAAPLFSNFVNDGGLFPNGVAAVLLTMITVNFSFQGTELIGIAAGESEQPEKTIPRA
CCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFKKVNKRGIPITALIVTIAVAGLSLLTSFFAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSVAGLSAVASWVIIALSQLRFRSQYVKDGGKLEDLKYKTPLYPIVPILALVTNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVIISLAFIPEQRMALYCGIPFIICCYVYYYINKKRQKVMKVEMDKAYETNN
HHEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]