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The map label for this gene is yfkJ [H]

Identifier: 152974227

GI number: 152974227

Start: 449548

End: 450012

Strand: Direct

Name: yfkJ [H]

Synonym: Bcer98_0393

Alternate gene names: 152974227

Gene position: 449548-450012 (Clockwise)

Preceding gene: 152974226

Following gene: 152974228

Centisome position: 11.0

GC content: 36.56

Gene sequence:

>465_bases
GTGATTCAAGTATTGTTTGTTTGTCTTGGAAACATTTGTCGGTCACCTATGGCAGAGGCGATTTTTAGAAAACTTGTTAG
AAACGAAGGGTTAGAAAATGAGATTCAAATTGATTCTGCTGGGACAGGAGATTGGCATATTGGACAGCCGCCTCATAAAG
GAACGCAAAAAATTTTAACAGAAAATGAAGTCTCTTTTGAAGGAATTAAAGCACGTCAAATAGAAAAAGAAGACTTAACA
AAGTTTGATTATATTATTGCCATGGACAATAGGAATATAGTGGATTTAGAAAAAATTGGTAAATGTGGAGGCTATATTGG
TAGACTGTCCGATTTTGTTCCAGATAGTGGCTGGACAGATGTTCCTGACCCTTATTTTACAGGGAACTTTCAAGAAGTAT
ACGACCTTGTAACAGAAGGGTGCGCAAAGTTATTAACATTCATTCGCAATGAGCAAGGAATATGA

Upstream 100 bases:

>100_bases
TTTTCAATCCTATTAAATTAGTAGGAATTTCCTTTATAATTAATCATTGGTTGTTTATACTATATGTATATAAGAAAGCA
ACAAGAAGGGAAGAACAAAT

Downstream 100 bases:

>100_bases
GTAAGTTTAGAAAGACATACTTTCTAACATAAGAAAAAGAAAGGGTGAAGGAATATGGCAAAAAAGAATAATATAGCTCG
AAATATTGCAATTGGGGTAG

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MIQVLFVCLGNICRSPMAEAIFRKLVRNEGLENEIQIDSAGTGDWHIGQPPHKGTQKILTENEVSFEGIKARQIEKEDLT
KFDYIIAMDNRNIVDLEKIGKCGGYIGRLSDFVPDSGWTDVPDPYFTGNFQEVYDLVTEGCAKLLTFIRNEQGI

Sequences:

>Translated_154_residues
MIQVLFVCLGNICRSPMAEAIFRKLVRNEGLENEIQIDSAGTGDWHIGQPPHKGTQKILTENEVSFEGIKARQIEKEDLT
KFDYIIAMDNRNIVDLEKIGKCGGYIGRLSDFVPDSGWTDVPDPYFTGNFQEVYDLVTEGCAKLLTFIRNEQGI
>Mature_154_residues
MIQVLFVCLGNICRSPMAEAIFRKLVRNEGLENEIQIDSAGTGDWHIGQPPHKGTQKILTENEVSFEGIKARQIEKEDLT
KFDYIIAMDNRNIVDLEKIGKCGGYIGRLSDFVPDSGWTDVPDPYFTGNFQEVYDLVTEGCAKLLTFIRNEQGI

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=148, Percent_Identity=39.1891891891892, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI6005988, Length=148, Percent_Identity=39.8648648648649, Blast_Score=106, Evalue=9e-24,
Organism=Homo sapiens, GI96304457, Length=76, Percent_Identity=46.0526315789474, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1788375, Length=151, Percent_Identity=29.1390728476821, Blast_Score=67, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325330, Length=145, Percent_Identity=37.2413793103448, Blast_Score=90, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78706770, Length=154, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI78706772, Length=154, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=5e-23,
Organism=Drosophila melanogaster, GI78711846, Length=165, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=9e-23,
Organism=Drosophila melanogaster, GI78706766, Length=148, Percent_Identity=31.0810810810811, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706768, Length=148, Percent_Identity=31.0810810810811, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706764, Length=130, Percent_Identity=33.0769230769231, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648069, Length=152, Percent_Identity=32.8947368421053, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17359; Mature: 17359

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVLFVCLGNICRSPMAEAIFRKLVRNEGLENEIQIDSAGTGDWHIGQPPHKGTQKILT
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHH
ENEVSFEGIKARQIEKEDLTKFDYIIAMDNRNIVDLEKIGKCGGYIGRLSDFVPDSGWTD
CCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCC
VPDPYFTGNFQEVYDLVTEGCAKLLTFIRNEQGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIQVLFVCLGNICRSPMAEAIFRKLVRNEGLENEIQIDSAGTGDWHIGQPPHKGTQKILT
CHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHH
ENEVSFEGIKARQIEKEDLTKFDYIIAMDNRNIVDLEKIGKCGGYIGRLSDFVPDSGWTD
CCCCCCCCCHHHHCCHHHHHHHHEEEEECCCCEECHHHHHHHHHHHHHHHHHCCCCCCCC
VPDPYFTGNFQEVYDLVTEGCAKLLTFIRNEQGI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]