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The map label for this gene is alr [H]

Identifier: 152974082

GI number: 152974082

Start: 249928

End: 251097

Strand: Direct

Name: alr [H]

Synonym: Bcer98_0238

Alternate gene names: 152974082

Gene position: 249928-251097 (Clockwise)

Preceding gene: 152974081

Following gene: 152974083

Centisome position: 6.12

GC content: 39.15

Gene sequence:

>1170_bases
ATGGAAGAATTATCGTTTTACCGTGATACGTGGGTTGAAGTAGACTTGGATGCAATTTATAACAATGTTACGCGCATTAA
AGAATTAATCCGAGATGATGTAGAGATTTTTGCTGTAGTAAAAGGGAATGCATATGGACATGGCTATGTACCAGTAGCCA
AAACAGCATTAGAGGCCGGAGCGACAAGATTAGCAGTTGCGTTTTTAGATGAAGCTTTGATCCTTCGGCGTGCAGGTATT
ACAGCACCTATTTTAGTATTAGGTCCCTCAGCGCCACGCGATGTAAATGTAGCTGCGGAACATGATGTTACATTAACTGT
GTTTCAAAAAGAATGGGTGGAAGAAGCGATAAAACTTTGGAATAGTCCAGTTTCAATGAAATTTCATCTTAACTTTGATA
GTGGTATGGGGAGAATTGGGATTCGTGAGCGCGGGGAATTAGAAGGATTTTTAAGAAGTTTAGAAAATGCTCCATTTCTA
GAGTTTGAAGGAGTTTATACACATTTTGCAACAGCGGACGAAGTAGAGACATCGTACTTTGATAAACAATACAATACATT
TTTAGAGCAACTGAGTTGGTTGGAAAAACTTGGAGTCAGTCCGAGGCTTGTTCATGCAGCGAATAGTGCAGCTACTTTGA
GATTCCATGGAATTACATTTAATGCTGTTCGGATCGGAATTGCAATGTATGGGGTAACACCATCTATAGAAATAAGCCCT
TTTTTACCAATACAATTAGAAGCGGCCCTTTCTCTTCATTCAACTGTTGCACATATTAAGCAAGTTATGAAAGGAGATGG
GGTTAGCTATGGTGTTACGTATCAGACGAGGACGGAGGAGTGGATTGCTACCATACCGATTGGTTATGCGGATGGCTGGC
TTAGAAGATTACAAGGATTTAAAGTGCTTGTAAATGGAAAACGAGTTCCGATTGTAGGTAGAGTTACAATGGACCAATTG
ATGTTGCGTCTTCCTTATAAAGTTTCTCTTGGTACAAAAGTCACACTTATTGGCAAACAAGGGAGTGAATATATTCACGC
AGCAGAAGTTGCGGAGTACACAAGTACGATTAATTACGAGATTATAACAACGACTAGTTTTCGTGTACCGCGTATATTCA
TTCGAAATGGGAAAGTAGTAGAAGTAATCAACTATTTGAATGATATATAA

Upstream 100 bases:

>100_bases
ATATACACCACGTTTTTTCTTACTTCAAGGAATGGATTTCGTGAAAAGTTGCATATAAAAGAATAAGCTTCGTATATCTT
ATATAAGGAAGTGTTTTTTT

Downstream 100 bases:

>100_bases
AAGAAGTATTTAAGATTAGCTCGTAGGCATAAAGGTATTATATGATGTTGAAATTAGAAAAGGAAAAATAAAAGAGAATG
AATGTTTTGTTTGTGAATTG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MEELSFYRDTWVEVDLDAIYNNVTRIKELIRDDVEIFAVVKGNAYGHGYVPVAKTALEAGATRLAVAFLDEALILRRAGI
TAPILVLGPSAPRDVNVAAEHDVTLTVFQKEWVEEAIKLWNSPVSMKFHLNFDSGMGRIGIRERGELEGFLRSLENAPFL
EFEGVYTHFATADEVETSYFDKQYNTFLEQLSWLEKLGVSPRLVHAANSAATLRFHGITFNAVRIGIAMYGVTPSIEISP
FLPIQLEAALSLHSTVAHIKQVMKGDGVSYGVTYQTRTEEWIATIPIGYADGWLRRLQGFKVLVNGKRVPIVGRVTMDQL
MLRLPYKVSLGTKVTLIGKQGSEYIHAAEVAEYTSTINYEIITTTSFRVPRIFIRNGKVVEVINYLNDI

Sequences:

>Translated_389_residues
MEELSFYRDTWVEVDLDAIYNNVTRIKELIRDDVEIFAVVKGNAYGHGYVPVAKTALEAGATRLAVAFLDEALILRRAGI
TAPILVLGPSAPRDVNVAAEHDVTLTVFQKEWVEEAIKLWNSPVSMKFHLNFDSGMGRIGIRERGELEGFLRSLENAPFL
EFEGVYTHFATADEVETSYFDKQYNTFLEQLSWLEKLGVSPRLVHAANSAATLRFHGITFNAVRIGIAMYGVTPSIEISP
FLPIQLEAALSLHSTVAHIKQVMKGDGVSYGVTYQTRTEEWIATIPIGYADGWLRRLQGFKVLVNGKRVPIVGRVTMDQL
MLRLPYKVSLGTKVTLIGKQGSEYIHAAEVAEYTSTINYEIITTTSFRVPRIFIRNGKVVEVINYLNDI
>Mature_389_residues
MEELSFYRDTWVEVDLDAIYNNVTRIKELIRDDVEIFAVVKGNAYGHGYVPVAKTALEAGATRLAVAFLDEALILRRAGI
TAPILVLGPSAPRDVNVAAEHDVTLTVFQKEWVEEAIKLWNSPVSMKFHLNFDSGMGRIGIRERGELEGFLRSLENAPFL
EFEGVYTHFATADEVETSYFDKQYNTFLEQLSWLEKLGVSPRLVHAANSAATLRFHGITFNAVRIGIAMYGVTPSIEISP
FLPIQLEAALSLHSTVAHIKQVMKGDGVSYGVTYQTRTEEWIATIPIGYADGWLRRLQGFKVLVNGKRVPIVGRVTMDQL
MLRLPYKVSLGTKVTLIGKQGSEYIHAAEVAEYTSTINYEIITTTSFRVPRIFIRNGKVVEVINYLNDI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=379, Percent_Identity=31.6622691292876, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1787439, Length=375, Percent_Identity=30.4, Blast_Score=129, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 43579; Mature: 43579

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEELSFYRDTWVEVDLDAIYNNVTRIKELIRDDVEIFAVVKGNAYGHGYVPVAKTALEAG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHC
ATRLAVAFLDEALILRRAGITAPILVLGPSAPRDVNVAAEHDVTLTVFQKEWVEEAIKLW
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHH
NSPVSMKFHLNFDSGMGRIGIRERGELEGFLRSLENAPFLEFEGVYTHFATADEVETSYF
CCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHH
DKQYNTFLEQLSWLEKLGVSPRLVHAANSAATLRFHGITFNAVRIGIAMYGVTPSIEISP
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECEEEEHEEEEEEEECCCCCCEECC
FLPIQLEAALSLHSTVAHIKQVMKGDGVSYGVTYQTRTEEWIATIPIGYADGWLRRLQGF
CCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCHHHHHHHCCC
KVLVNGKRVPIVGRVTMDQLMLRLPYKVSLGTKVTLIGKQGSEYIHAAEVAEYTSTINYE
EEEECCCEEEEEECCCHHHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEE
IITTTSFRVPRIFIRNGKVVEVINYLNDI
EEEECCCCCCEEEEECCCEEHHHHHHHCC
>Mature Secondary Structure
MEELSFYRDTWVEVDLDAIYNNVTRIKELIRDDVEIFAVVKGNAYGHGYVPVAKTALEAG
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCHHHHHHHHHC
ATRLAVAFLDEALILRRAGITAPILVLGPSAPRDVNVAAEHDVTLTVFQKEWVEEAIKLW
CHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEEHHHHHHHHHHHHH
NSPVSMKFHLNFDSGMGRIGIRERGELEGFLRSLENAPFLEFEGVYTHFATADEVETSYF
CCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCEEEECCHHHHHHHHH
DKQYNTFLEQLSWLEKLGVSPRLVHAANSAATLRFHGITFNAVRIGIAMYGVTPSIEISP
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEECEEEEHEEEEEEEECCCCCCEECC
FLPIQLEAALSLHSTVAHIKQVMKGDGVSYGVTYQTRTEEWIATIPIGYADGWLRRLQGF
CCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCHHHHHHHCCC
KVLVNGKRVPIVGRVTMDQLMLRLPYKVSLGTKVTLIGKQGSEYIHAAEVAEYTSTINYE
EEEECCCEEEEEECCCHHHHHHHCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHCCEEE
IITTTSFRVPRIFIRNGKVVEVINYLNDI
EEEECCCCCCEEEEECCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2835089; 2496744; 3730360; 9063881; 9671513; 10079072; 10194319; 10502689 [H]