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The map label for this gene is emrR [H]

Identifier: 152971540

GI number: 152971540

Start: 3311615

End: 3312046

Strand: Direct

Name: emrR [H]

Synonym: KPN_03013

Alternate gene names: 152971540

Gene position: 3311615-3312046 (Clockwise)

Preceding gene: 152971539

Following gene: 152971541

Centisome position: 62.31

GC content: 52.78

Gene sequence:

>432_bases
ATGCATATGCAAGGTAAGCTGCTGGAAAATCGCAATAAAATGCTCAAAGCGCAGGGAATTAACGAGACATTATTTATGGC
GCTGATTACGCTGGAGTCACAGGAAAACCACAGCATCCAGCCGTCCGAGCTGAGCTGTGCGCTGGGCTCGTCACGTACCA
ACGCCACCCGTATCGCTGATGAACTGGAAAAACGCGGCTGGATTGAGCGCCGCGAGAGCGATAACGATCGTCGCTGTTTG
CATCTGCAACTGACCGAAAAGGGCCATCAGTTTTTGCGTGAAGTCCTGCCGCCGCAGCATAACTGCCTGCATCAGCTGTG
GTCTTCACTTAGCACCAGCGAAAAAGATCAGCTCGAACACATCACCCGCAAACTCCTGAGCCGCCTTGATCAGATGGAAG
AAGAAGGCGTGCTAGCGGACTCTCTACGCTAA

Upstream 100 bases:

>100_bases
AATGGATAGTTCGTTTACTCCCATTGAGCAAATGCTCAAGTTCCGCGCCAGCCGCCATGAAGATTTCCCGTTTCAGGAGA
TCCTGTTAACTCGTCTTTGC

Downstream 100 bases:

>100_bases
GGGCGGCGTCGCTCAGCCCATTTTTACGTTGCAAGGAAAACAGCCAGGCCAGCAGATCTCTGCTGGCCTTTCTGATAAAC
AGGTCGGCTCAGCCGATGTG

Product: transcriptional repressor MprA

Products: NA

Alternate protein names: Protein emrR [H]

Number of amino acids: Translated: 143; Mature: 143

Protein sequence:

>143_residues
MHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCL
HLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGVLADSLR

Sequences:

>Translated_143_residues
MHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCL
HLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGVLADSLR
>Mature_143_residues
MHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIERRESDNDRRCL
HLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEHITRKLLSRLDQMEEEGVLADSLR

Specific function: Negative regulator of the multidrug operon emrAB [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789040, Length=142, Percent_Identity=91.5492957746479, Blast_Score=271, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16598; Mature: 16598

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIAD
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHH
ELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEH
HHHHCCCHHHCCCCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
ITRKLLSRLDQMEEEGVLADSLR
HHHHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MHMQGKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIAD
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHH
ELEKRGWIERRESDNDRRCLHLQLTEKGHQFLREVLPPQHNCLHQLWSSLSTSEKDQLEH
HHHHCCCHHHCCCCCCCEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
ITRKLLSRLDQMEEEGVLADSLR
HHHHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]