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The map label for this gene is intA [H]

Identifier: 152971470

GI number: 152971470

Start: 3231820

End: 3233067

Strand: Direct

Name: intA [H]

Synonym: KPN_02943

Alternate gene names: 152971470

Gene position: 3231820-3233067 (Clockwise)

Preceding gene: 152971469

Following gene: 152971471

Centisome position: 60.8

GC content: 56.49

Gene sequence:

>1248_bases
ATGCCTAAGGTATTGAAATCCCTAACCAATACCGAGATCGCTGCCGCCAAACCGCAGAAGACTGAGTATATGCTGCGCGA
TGGCGACGGACTGGCGTTGTTGATTAAGCCATCCGGCAGAAAGATCTGGTACTTCGAATACGCTCCCCCGGCGCTGAAAA
AACGGACCAAAATCAGCATTGGCCCCTACCCGGTAGTCACCCTCGCCATGGCGCGAGATTTCAGGTTGCAATACCGGCGT
TTACTTGTGCAGGGCATCGACCCGCAGGCCCATCTGGAGCAGGTTGCAGAGGAGCAACGACTCCAGAATGAATGCACGCT
GGAAAAAGTTGCGGAACAGTGGCTCAAAGAGAAAAAACGGACTAGCGATCTTAGCGAAGATCACGCCAAAGATGTCTGGC
GCTCGCTGGAGATGCACGTCTTCCCCTCTTTGGGTAACACGCCCGTCACTGAGATCCGCCCGAAGATGCTCAAGGAACAC
CTCACGCTACTGGAAGAACAGGGCATACTGGAAACGCTGCGGCGGGTGATCTCACGGCTCAATGAAATCTTCCGTTTTGC
CATCTCCGAAGAGCTCATCGAGTTCAATCCGGCTGACAACCTGGTCGCCCGCTTCAAGAAACCGAAAAAGCAGAACATGC
CCGCCCTTCACCCCAGTGAACTGGGTAGGCTGATGCTGGCCTTACAGAACGCTTCTATCCGCAAGGAAACCCGCTGCCTT
ATCGAATGGGAGCTACTGACCTGGGTTCGCCCCGGCGAAGCCGTCAGCGCCCGCTGGTGCGACATCGACATGAAAAAAGC
GGAATGGCGCATCCCCGACACCTTTATGAAGATGAACCGTTCGCACACTGTGCCTCTCAGCAAACAGGCGCTGCGCGTTC
TTCAGATCATGGAGCCCGTCAGCCGCCATCGTCCGTGGGTGTTCCCCAGCATCCGCAAACCACTGGAGCATATGCACCAG
CAGACCGCGAACGCCGCGCTTATTCGTATGGGGTTCGGCGGTGAGCTGGTTGCCCACGGTATGCGCAGTATTGCCCGAAC
GGCGGGAGCAGGTCATTTCCCCCGTGAAGTTCTGGAATCTGCGCTGGCACACCAGAAAGAAGACGAGATCGAAGCGGCCT
ACAACCGCAGCGACTATCTGGAACAAAGGCGACCGCTGATGCAGTGGTGGGGAAACTACGTTGATGCCGCCAGACGGCAG
GCATTGCTCGGTGAAGAAGAACCGCTGCGGATCGTGGAAGGAGAATAA

Upstream 100 bases:

>100_bases
TTGTTGCATGTGTGGTCATGATCTCTGTATGAATCTTGAGCATTATGTATCTTGTTTTGTACCGCGTTGCCTGGACGCTA
AAAAAACAAGGTGCAAAAAC

Downstream 100 bases:

>100_bases
TGTGACCAGTCCCATTCGTCAGAATCTGTTTGAACGGGAATGCGATATGCCGCTGCTGGAAGCGCGGCATCTCGCCCTTC
TGCTTCTCGGCCTTGATGCT

Product: putative integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MPKVLKSLTNTEIAAAKPQKTEYMLRDGDGLALLIKPSGRKIWYFEYAPPALKKRTKISIGPYPVVTLAMARDFRLQYRR
LLVQGIDPQAHLEQVAEEQRLQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEH
LTLLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQ
QTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQ
ALLGEEEPLRIVEGE

Sequences:

>Translated_415_residues
MPKVLKSLTNTEIAAAKPQKTEYMLRDGDGLALLIKPSGRKIWYFEYAPPALKKRTKISIGPYPVVTLAMARDFRLQYRR
LLVQGIDPQAHLEQVAEEQRLQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEH
LTLLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQ
QTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQ
ALLGEEEPLRIVEGE
>Mature_414_residues
PKVLKSLTNTEIAAAKPQKTEYMLRDGDGLALLIKPSGRKIWYFEYAPPALKKRTKISIGPYPVVTLAMARDFRLQYRRL
LVQGIDPQAHLEQVAEEQRLQNECTLEKVAEQWLKEKKRTSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHL
TLLEEQGILETLRRVISRLNEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCLI
EWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPVSRHRPWVFPSIRKPLEHMHQQ
TANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLESALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQA
LLGEEEPLRIVEGE

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=405, Percent_Identity=48.8888888888889, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI145693166, Length=419, Percent_Identity=34.3675417661098, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1788690, Length=395, Percent_Identity=28.8607594936709, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 48066; Mature: 47935

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVLKSLTNTEIAAAKPQKTEYMLRDGDGLALLIKPSGRKIWYFEYAPPALKKRTKISI
CCHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCC
GPYPVVTLAMARDFRLQYRRLLVQGIDPQAHLEQVAEEQRLQNECTLEKVAEQWLKEKKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHLTLLEEQGILETLRRVISRL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
NEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPV
EEEHHHHHCCCCCHHCCEECCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLES
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
ALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGEEEPLRIVEGE
HHHCCCHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
>Mature Secondary Structure 
PKVLKSLTNTEIAAAKPQKTEYMLRDGDGLALLIKPSGRKIWYFEYAPPALKKRTKISI
CHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEEEECCCCEEEEEECCCHHHHHCCCCCC
GPYPVVTLAMARDFRLQYRRLLVQGIDPQAHLEQVAEEQRLQNECTLEKVAEQWLKEKKR
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSDLSEDHAKDVWRSLEMHVFPSLGNTPVTEIRPKMLKEHLTLLEEQGILETLRRVISRL
HCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
NEIFRFAISEELIEFNPADNLVARFKKPKKQNMPALHPSELGRLMLALQNASIRKETRCL
HHHHHHHHHHHHHHCCCHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHH
IEWELLTWVRPGEAVSARWCDIDMKKAEWRIPDTFMKMNRSHTVPLSKQALRVLQIMEPV
EEEHHHHHCCCCCHHCCEECCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHH
SRHRPWVFPSIRKPLEHMHQQTANAALIRMGFGGELVAHGMRSIARTAGAGHFPREVLES
HHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
ALAHQKEDEIEAAYNRSDYLEQRRPLMQWWGNYVDAARRQALLGEEEPLRIVEGE
HHHCCCHHHHHHHHCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]