| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is xseA [H]
Identifier: 152971366
GI number: 152971366
Start: 3112649
End: 3114040
Strand: Direct
Name: xseA [H]
Synonym: KPN_02835
Alternate gene names: 152971366
Gene position: 3112649-3114040 (Clockwise)
Preceding gene: 152971363
Following gene: 152971382
Centisome position: 58.56
GC content: 61.85
Gene sequence:
>1392_bases ATGTTACCCTCTCAATCCCCCGCAATTTTTACCGTAAGCCGCCTCAATCAGACGGTGCGTCTGCTGCTTGAGCGCGAAAT GGGCCAGGTTTGGATCAGCGGCGAGATCTCTAACTTCAGCCAGCCTTCTTCCGGCCACTGGTACTTCACCTTAAAAGACG ATAACGCCCAGGTGCGCTGCGCGATGTTCCGCAACAGCAACCGCCGGGTGACGTTTCGCCCACAGCACGGGCAGCAGGTG CTGGTTCGCGCCAACATCACCCTGTATGAGCCGCGCGGCGACTACCAGATTATCGTCGAAAGCATGCAGCCCGCCGGCGA AGGGTTATTACAGCAGAAGTATGAGCAGCTCAAAGCGCAGTTAACGGCGGAAGGACTGTTCGAGCAAAAACATAAGCAGG CGCTCCCCTCCCCCGCCCACTGCGTCGGCGTCATCACCTCGAAAACCGGTGCGGCGCTGCACGATATTCTCCATGTTCTC AGGCGCCGCGATCCCGGGCTGCCGGTGATCATCTACCCAACCTCGGTCCAGGGTGACGACGCCCCCGGGCAGATTGTGCG CGCCATCGCGCTGGCCAACGCGCGCCAGGAGTGTGACGTACTGATTGTCGGACGCGGCGGCGGTTCGCTGGAGGATCTGT GGAGTTTTAACGATGAGCGGGTGGCGCGGGCTATTTTCGCCAGCCAGATCCCTATCGTCAGCGCCGTCGGCCATGAAACC GACGTCACGATCGCTGATTTTGTTGCCGACCTGCGGGCACCGACTCCCTCAGCCGCCGCGGAAATCGTCAGCCGCAACCA GCAGGAGCTGCTGCGCCAGCTGCAGTCCGGACAGCAGCGGCTGGAGATGGCGATGGACTATTTCCTCGCCAGTCGCCAGC GCCGTTTTACCCAGCTGTTCCATCGCCTGCAGCAACAGCATCCACAGCTGCGCTTGGCCCGCCAGCAGACCGCCCTGGAA CGCCTGCGCCAGCGGATGCGTATCGCCGTGGAGTCACAGCTTAAGCGCGCAGAACAGCGGCAAAAGCGCACCGTTCAGCG TCTGAATCACTACAACCCGCAGCCACGGATCCACCGCGCGCAGTCGCGGATCCAGCAGCTGGAATACCGGCTGGCGGAAA TTATGCGTGGCCGCCTCAGCGAGCGGCGTGAACGGTTTGGCAACGCGGTGACCCATCTGGAGGCGGTGAGCCCCTTAGCC ACCCTGGCGCGGGGCTACAGCGTCACCTCGGTGAGCGACGGTACGGTGCTGAAGCAGACAAAACAGGTCAAAACCGGCGA TCTGCTCACCACCCGCCTGAAAGACGGCTGGGTCGAAAGCGAAGTGAAGCAGATCGCGCCGGTGAAAAAAACGCGGGCCA GAAAGCCTTCGCCCACTAAACCAGCGGAATAA
Upstream 100 bases:
>100_bases GATTGCATCTACCCTTTTTTGCAAATAATACTTGCCATCCCCTCTGAGCGCGTTACTATCGACTGAATAACCTGCTGATT TAAAGTTTGATCTTGCTCAC
Downstream 100 bases:
>100_bases ATTCCACCCGTTTTTTCGAGATAAGGCCATGCCCATGCTGGCAAAAGTAATCCACCGCGCCGCACGCCTTCAGCACCTCC AGCGGCTGGTGGCATTCCGG
Product: exodeoxyribonuclease VII large subunit
Products: NA
Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]
Number of amino acids: Translated: 463; Mature: 463
Protein sequence:
>463_residues MLPSQSPAIFTVSRLNQTVRLLLEREMGQVWISGEISNFSQPSSGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAQLTAEGLFEQKHKQALPSPAHCVGVITSKTGAALHDILHVL RRRDPGLPVIIYPTSVQGDDAPGQIVRAIALANARQECDVLIVGRGGGSLEDLWSFNDERVARAIFASQIPIVSAVGHET DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQLQSGQQRLEMAMDYFLASRQRRFTQLFHRLQQQHPQLRLARQQTALE RLRQRMRIAVESQLKRAEQRQKRTVQRLNHYNPQPRIHRAQSRIQQLEYRLAEIMRGRLSERRERFGNAVTHLEAVSPLA TLARGYSVTSVSDGTVLKQTKQVKTGDLLTTRLKDGWVESEVKQIAPVKKTRARKPSPTKPAE
Sequences:
>Translated_463_residues MLPSQSPAIFTVSRLNQTVRLLLEREMGQVWISGEISNFSQPSSGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAQLTAEGLFEQKHKQALPSPAHCVGVITSKTGAALHDILHVL RRRDPGLPVIIYPTSVQGDDAPGQIVRAIALANARQECDVLIVGRGGGSLEDLWSFNDERVARAIFASQIPIVSAVGHET DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQLQSGQQRLEMAMDYFLASRQRRFTQLFHRLQQQHPQLRLARQQTALE RLRQRMRIAVESQLKRAEQRQKRTVQRLNHYNPQPRIHRAQSRIQQLEYRLAEIMRGRLSERRERFGNAVTHLEAVSPLA TLARGYSVTSVSDGTVLKQTKQVKTGDLLTTRLKDGWVESEVKQIAPVKKTRARKPSPTKPAE >Mature_463_residues MLPSQSPAIFTVSRLNQTVRLLLEREMGQVWISGEISNFSQPSSGHWYFTLKDDNAQVRCAMFRNSNRRVTFRPQHGQQV LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAQLTAEGLFEQKHKQALPSPAHCVGVITSKTGAALHDILHVL RRRDPGLPVIIYPTSVQGDDAPGQIVRAIALANARQECDVLIVGRGGGSLEDLWSFNDERVARAIFASQIPIVSAVGHET DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQLQSGQQRLEMAMDYFLASRQRRFTQLFHRLQQQHPQLRLARQQTALE RLRQRMRIAVESQLKRAEQRQKRTVQRLNHYNPQPRIHRAQSRIQQLEYRLAEIMRGRLSERRERFGNAVTHLEAVSPLA TLARGYSVTSVSDGTVLKQTKQVKTGDLLTTRLKDGWVESEVKQIAPVKKTRARKPSPTKPAE
Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]
COG id: COG1570
COG function: function code L; Exonuclease VII, large subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the xseA family [H]
Homologues:
Organism=Escherichia coli, GI1788856, Length=454, Percent_Identity=84.5814977973568, Blast_Score=793, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003753 - InterPro: IPR020579 - InterPro: IPR004365 [H]
Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]
EC number: =3.1.11.6 [H]
Molecular weight: Translated: 52482; Mature: 52482
Theoretical pI: Translated: 10.87; Mature: 10.87
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLPSQSPAIFTVSRLNQTVRLLLEREMGQVWISGEISNFSQPSSGHWYFTLKDDNAQVRC CCCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEE AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAQ EEEECCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH LTAEGLFEQKHKQALPSPAHCVGVITSKTGAALHDILHVLRRRDPGLPVIIYPTSVQGDD HHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCC APGQIVRAIALANARQECDVLIVGRGGGSLEDLWSFNDERVARAIFASQIPIVSAVGHET CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCC DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQLQSGQQRLEMAMDYFLASRQRRFTQLF CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HRLQQQHPQLRLARQQTALERLRQRMRIAVESQLKRAEQRQKRTVQRLNHYNPQPRIHRA HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH QSRIQQLEYRLAEIMRGRLSERRERFGNAVTHLEAVSPLATLARGYSVTSVSDGTVLKQT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHH KQVKTGDLLTTRLKDGWVESEVKQIAPVKKTRARKPSPTKPAE HHCCCCCHHHHHHHCCHHHHHHHHHCCHHHHHCCCCCCCCCCC >Mature Secondary Structure MLPSQSPAIFTVSRLNQTVRLLLEREMGQVWISGEISNFSQPSSGHWYFTLKDDNAQVRC CCCCCCCCEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEE AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAQ EEEECCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHEEHHCCCCCHHHHHHHHHHHHH LTAEGLFEQKHKQALPSPAHCVGVITSKTGAALHDILHVLRRRDPGLPVIIYPTSVQGDD HHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCC APGQIVRAIALANARQECDVLIVGRGGGSLEDLWSFNDERVARAIFASQIPIVSAVGHET CHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHCCCCCC DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQLQSGQQRLEMAMDYFLASRQRRFTQLF CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HRLQQQHPQLRLARQQTALERLRQRMRIAVESQLKRAEQRQKRTVQRLNHYNPQPRIHRA HHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH QSRIQQLEYRLAEIMRGRLSERRERFGNAVTHLEAVSPLATLARGYSVTSVSDGTVLKQT HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHH KQVKTGDLLTTRLKDGWVESEVKQIAPVKKTRARKPSPTKPAE HHCCCCCHHHHHHHCCHHHHHHHHHCCHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA