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The map label for this gene is flk [H]

Identifier: 152971249

GI number: 152971249

Start: 2980691

End: 2981581

Strand: Direct

Name: flk [H]

Synonym: KPN_02711

Alternate gene names: 152971249

Gene position: 2980691-2981581 (Clockwise)

Preceding gene: 152971233

Following gene: 152971252

Centisome position: 56.08

GC content: 64.87

Gene sequence:

>891_bases
ATGCAGCAACGCACCGTTCTGGAGCGACTGATCACGCGCCTGGTGGCGCTGACCTCGCAGCAGAACGCGGAAGTGTGGGC
CTGCGTCAAACATGACCTCGGACTGAAAGGCGACTCGCCCCTGCTGGCCTGCCATTTCAGCGCCGCGGAGGCCAGTCTCA
ACCAGCGCTTAGCCGCCGCTCAGGATAATCATCATCATCGCCAGACCTTAGCGCAGCTCAGCGATCTGCTCGGTCAGGGC
AATAACCGCCAGGCGGTGAGCGATTATATTCGTCAGCATTATGGGCAAACGGCGCTGCATGCCCTTAGCCAGACGCAGCT
GGAGACCATTCTGCATCTGCTGCAGCATGGCCAGCTGTCGATCCCGCAGCCGCAGCAGCGCCCGCCGACCCTGCGCCCGC
TGTTGCCAGCCGAGCATAATACGCTCAATCAGCTGGTGACTAAGCTGGCGGCCGCCACCGGCGAACCAAGCAAGCTGATT
TGGCAATCCATGCTGGAGCTTTGCGGCGTCAAGTCCGGGGAGCTGATCCCGGCGACGCACTTCCTGCCGCTTTCGTACTG
GCTGCAGGCGCGGCAAACGCTGAGTGCGCAAAGCGCGCCGACGCTCACCTCGCTGCAGGGAGCGCTCAAGCAGCCGCTGG
AGGCCGCGGAGTGGCAGACAATTGTCGACTTTGCCCGTCGCAGCTGGCAGGTCACGCCGCGGACCACGCTGAGCCCGGCG
CAGATCCTGGCGCTGCTGAACAAGGTGTTTGTGCTGCGGGTGGCCCGCGCCCAGGAGACGCTGGCCATCCCGCAGGAGGA
GCCTGTCGCCAGGCGGACGTGGAGCGCTAAGCCGTGGCAGCTGGCGCTGGGCGCGGTTGTCCTGCTCCTTGTGCTGTGGC
TCCTGCTGTAG

Upstream 100 bases:

>100_bases
GAAAGGATGAATCATGACGCACCCCCTTGCTGATATGCCAGACCGTCCTCCAGGGCGAGGCCCATCAGGCACTGCCGCCA
CCGGCGAACCTTCGCTTTCC

Downstream 100 bases:

>100_bases
TCCAGCAGCCACCGGCGGCGTTTACGGCTCCCCTTCATGCCAAACGCCGCGGTGTTTCCTACAGCGTTTTCAGGCCGGAC
AATAACCTAGCGGCGAAATG

Product: flagella biosynthesis regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQQRTVLERLITRLVALTSQQNAEVWACVKHDLGLKGDSPLLACHFSAAEASLNQRLAAAQDNHHHRQTLAQLSDLLGQG
NNRQAVSDYIRQHYGQTALHALSQTQLETILHLLQHGQLSIPQPQQRPPTLRPLLPAEHNTLNQLVTKLAAATGEPSKLI
WQSMLELCGVKSGELIPATHFLPLSYWLQARQTLSAQSAPTLTSLQGALKQPLEAAEWQTIVDFARRSWQVTPRTTLSPA
QILALLNKVFVLRVARAQETLAIPQEEPVARRTWSAKPWQLALGAVVLLLVLWLLL

Sequences:

>Translated_296_residues
MQQRTVLERLITRLVALTSQQNAEVWACVKHDLGLKGDSPLLACHFSAAEASLNQRLAAAQDNHHHRQTLAQLSDLLGQG
NNRQAVSDYIRQHYGQTALHALSQTQLETILHLLQHGQLSIPQPQQRPPTLRPLLPAEHNTLNQLVTKLAAATGEPSKLI
WQSMLELCGVKSGELIPATHFLPLSYWLQARQTLSAQSAPTLTSLQGALKQPLEAAEWQTIVDFARRSWQVTPRTTLSPA
QILALLNKVFVLRVARAQETLAIPQEEPVARRTWSAKPWQLALGAVVLLLVLWLLL
>Mature_296_residues
MQQRTVLERLITRLVALTSQQNAEVWACVKHDLGLKGDSPLLACHFSAAEASLNQRLAAAQDNHHHRQTLAQLSDLLGQG
NNRQAVSDYIRQHYGQTALHALSQTQLETILHLLQHGQLSIPQPQQRPPTLRPLLPAEHNTLNQLVTKLAAATGEPSKLI
WQSMLELCGVKSGELIPATHFLPLSYWLQARQTLSAQSAPTLTSLQGALKQPLEAAEWQTIVDFARRSWQVTPRTTLSPA
QILALLNKVFVLRVARAQETLAIPQEEPVARRTWSAKPWQLALGAVVLLLVLWLLL

Specific function: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor flgM upon sensing ring completion or hook elongation. Flk could inhibit flgM secretion by acting as a braking system for the flagellar- associated ty

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flk family [H]

Homologues:

Organism=Escherichia coli, GI1788661, Length=299, Percent_Identity=54.180602006689, Blast_Score=283, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32901; Mature: 32901

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQRTVLERLITRLVALTSQQNAEVWACVKHDLGLKGDSPLLACHFSAAEASLNQRLAAA
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHH
QDNHHHRQTLAQLSDLLGQGNNRQAVSDYIRQHYGQTALHALSQTQLETILHLLQHGQLS
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
IPQPQQRPPTLRPLLPAEHNTLNQLVTKLAAATGEPSKLIWQSMLELCGVKSGELIPATH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHH
FLPLSYWLQARQTLSAQSAPTLTSLQGALKQPLEAAEWQTIVDFARRSWQVTPRTTLSPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
QILALLNKVFVLRVARAQETLAIPQEEPVARRTWSAKPWQLALGAVVLLLVLWLLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQQRTVLERLITRLVALTSQQNAEVWACVKHDLGLKGDSPLLACHFSAAEASLNQRLAAA
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHH
QDNHHHRQTLAQLSDLLGQGNNRQAVSDYIRQHYGQTALHALSQTQLETILHLLQHGQLS
HCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCC
IPQPQQRPPTLRPLLPAEHNTLNQLVTKLAAATGEPSKLIWQSMLELCGVKSGELIPATH
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHH
FLPLSYWLQARQTLSAQSAPTLTSLQGALKQPLEAAEWQTIVDFARRSWQVTPRTTLSPA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
QILALLNKVFVLRVARAQETLAIPQEEPVARRTWSAKPWQLALGAVVLLLVLWLLL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9079927; 11677609 [H]