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The map label for this gene is nylB [H]

Identifier: 152971159

GI number: 152971159

Start: 2877275

End: 2878582

Strand: Direct

Name: nylB [H]

Synonym: KPN_02620

Alternate gene names: 152971159

Gene position: 2877275-2878582 (Clockwise)

Preceding gene: 152971157

Following gene: 152971161

Centisome position: 54.13

GC content: 60.24

Gene sequence:

>1308_bases
ATGGCAAACGAGGAAATGACAATGATAAGAAAACCACTGGCCCTGGCATTAATATTGGCGGCGCTGCCGGCGGCGGCAAT
GGCGCAACACTGCGGCAGCCTGACGCTGGATGTCTGCCCAACGCCTTACGATCAAACGCTACCCGCGGCCAAAGACATGC
TCAGCTGGGATCAGACTTCACGCGTGATTGGCTTTCGCAATCACTATCGCAACTATGCCGGCGATGTCTTCCGCCACGGC
GCCTCGACGCCGCTGGAGCGCGCTGAAAAACAACTGACCGATGCCCGCTATACGCTCAACGGCCACACCTGGAATTTGCA
GGATTACCTGAAGCGCGAGAACGTCAGCGGTATGCTGGTGCTGAAAGATGGTAAAGTCGCCTGGAAATATCTCGCCGAAG
GTAATACCGACACCACCCTGTGGACCTCGCGCTCGGTAGGCAAATCGGTGGTCTCGACGCTGGTCGGTATCGCCATTCGA
CAGGGTAAAATCCACTCCCTTGATGACCTGATTACCGTTTATGAACCCGAACTGAAAGGCACCGCCTGGGACGGCGTAAC
GCTGAAGCAGTTGATTCAACACACCAGCGGGGTGGAATGGAATGAAGACTACACCGACCCGCAGTCGCATTTCGCCCGCC
TGACCCAGTGTGAAGCGCACCCCGGCGTCTATGCCTGCGTGCGTAAGATCGTCACCGGCCTGGCGCGTCAACACCCGGCG
GGCGAGCAGTGGTCCTACTCTTCCGGCGGCGCCTGGCTGCTTGGGGATATCCTGGAGCGCGCCACCGGCATGTCGCTGGC
CGCCTGGCTTGAACAGGCTCTATGGCAGCCGGCCGGGATGGCCCACGACGGCGTGTGGCATGCTTATCAGCAAGGGAAGC
ACGACGTCGGCGCCCACGGCTTTAACGCCACCCTTGAAGACTGGGGCCGCTTTGGTGAATTCGTCGCCCGTGACGGTCGG
TTAAGCAATGGCAAACAGCTGGTGCCGACTGGCTGGTTCGATCAAGCCGCCAGCTGGACCAAGGCGCTAAACTCGGTCTC
GGCAGCGCATCCGGAGGGTATTTACGGCTATCTGTGGTGGAATAACGCGATTCCGGCGAATGCGCAAAACGTACAGCCGA
CGCCGCAGGAAGGGCTTAAAGGGTCGCTGTGGGCGCTGGGGATCTACGGCCAGGTGATCATGGTGAACCGCGCGGAACAC
CTGGTGATCGTCCAGTGGTCGACCTGGCCGCAGGCGGAACCTTCCTTCAACGCTCAGCCGTTGGAAGCGGCGCTGATGTA
CAGCGCCATTGCCCGCGAGCTGCGTTAA

Upstream 100 bases:

>100_bases
TACTGTAGGGTTTTCATCCTTTTTCTCCCTTAAGGGGGAAAATCCCCCATGTGCTGATTTTAGCCGGCGCGCGCCGATTT
ATATACTGCGCAGCGAATCT

Downstream 100 bases:

>100_bases
CTCCCCGCTCCTTGCCGCTCAGCCGGCGAGGAGCGTGTCGGCATTCAGCGCCAGGTGTTGCAGCAGGATAATGGTTTTAG
CATCCATGATCTCGCCATCG

Product: putative beta-lactamase

Products: NA

Alternate protein names: Nylon oligomers-degrading enzyme EII [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTSRVIGFRNHYRNYAGDVFRHG
ASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKDGKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIR
QGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNEDYTDPQSHFARLTQCEAHPGVYACVRKIVTGLARQHPA
GEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGR
LSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYLWWNNAIPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEH
LVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR

Sequences:

>Translated_435_residues
MANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTSRVIGFRNHYRNYAGDVFRHG
ASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKDGKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIR
QGKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNEDYTDPQSHFARLTQCEAHPGVYACVRKIVTGLARQHPA
GEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGR
LSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYLWWNNAIPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEH
LVIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR
>Mature_434_residues
ANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTSRVIGFRNHYRNYAGDVFRHGA
STPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLVLKDGKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIRQ
GKIHSLDDLITVYEPELKGTAWDGVTLKQLIQHTSGVEWNEDYTDPQSHFARLTQCEAHPGVYACVRKIVTGLARQHPAG
EQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHGFNATLEDWGRFGEFVARDGRL
SNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYLWWNNAIPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHL
VIVQWSTWPQAEPSFNAQPLEAALMYSAIARELR

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.1.46 [H]

Molecular weight: Translated: 48191; Mature: 48060

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
RVIGFRNHYRNYAGDVFRHGASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEECCCEECHHHHHHHCCCCEEEE
LKDGKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIRQGKIHSLDDLITVYEPELKG
EECCCEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
TAWDGVTLKQLIQHTSGVEWNEDYTDPQSHFARLTQCEAHPGVYACVRKIVTGLARQHPA
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
GEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCC
FNATLEDWGRFGEFVARDGRLSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYLWW
CCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
NNAIPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQP
CCCCCCCCCCCCCCHHHCCCCCEEEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCH
LEAALMYSAIARELR
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANEEMTMIRKPLALALILAALPAAAMAQHCGSLTLDVCPTPYDQTLPAAKDMLSWDQTS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
RVIGFRNHYRNYAGDVFRHGASTPLERAEKQLTDARYTLNGHTWNLQDYLKRENVSGMLV
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCEEEECCCEECHHHHHHHCCCCEEEE
LKDGKVAWKYLAEGNTDTTLWTSRSVGKSVVSTLVGIAIRQGKIHSLDDLITVYEPELKG
EECCCEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCC
TAWDGVTLKQLIQHTSGVEWNEDYTDPQSHFARLTQCEAHPGVYACVRKIVTGLARQHPA
CCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCC
GEQWSYSSGGAWLLGDILERATGMSLAAWLEQALWQPAGMAHDGVWHAYQQGKHDVGAHG
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCC
FNATLEDWGRFGEFVARDGRLSNGKQLVPTGWFDQAASWTKALNSVSAAHPEGIYGYLWW
CCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEE
NNAIPANAQNVQPTPQEGLKGSLWALGIYGQVIMVNRAEHLVIVQWSTWPQAEPSFNAQP
CCCCCCCCCCCCCCHHHCCCCCEEEEEECCEEEEEECCCEEEEEEECCCCCCCCCCCCCH
LEAALMYSAIARELR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6646204; 6389532; 2512123 [H]