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The map label for this gene is yeiQ [H]

Identifier: 152971144

GI number: 152971144

Start: 2859671

End: 2861137

Strand: Direct

Name: yeiQ [H]

Synonym: KPN_02605

Alternate gene names: 152971144

Gene position: 2859671-2861137 (Clockwise)

Preceding gene: 152971142

Following gene: 152971145

Centisome position: 53.8

GC content: 62.51

Gene sequence:

>1467_bases
ATGACAACAATTGCAACCGCTACGCTACCGAAGAACGTGCAATACCCTCAATACGATCGCAGCCAGCTCCGCTCGCGTAT
TGTCCATTTCGGCTTTGGCGCGTTTCACCGCGCGCACCAGGCGCTGCTCACCGATCGCGTGCTGAATAACGTCGGCGGCG
ACTGGGGGATCTGTGAAATCAGTCTGTTCAGCGGCGACACGCTGATGAGCCAGCTTCGCGAACAGGACCATCTGTTTACC
GTGCTGGAAAAAGGCGCCGACGGCAACCAGCCCATTGTGATCGGCGCGGTGCACGAATGTCTGAACGCCAGGCTCGATTC
GCTGGCGGCGATTATCGAAAAATTTTGCGAGCCGCAGGTAGCGATTGTCTCGCTGACCATTACGGAAAAAGGCTACTGCA
TCGATCCGGCGACCGGGAAACTGGATCCGACGCATCCGCGCATTATTCACGATCTGGAGAATCCGACGCTGCCGCAGTCA
GCTCCCGGTATTTTAGTTGAAGCGCTGGCCCGCCGCCGGGAACGAGGCCTTCCGCCCTTTACCGTGCTCTCCTGCGATAA
TATCCCCGACAACGGTCACGTGGTAAAAAATGCCGTCCTCGGCATGGCGGAAAAACGCAGCCCGGCGCTGGCGGACTGGA
TCGCCGACAACGTCAGCTTCCCGGGCACCATGGTGGATCGTATTGTTCCTGCGGCCACACCGGAGTCACTGGCGGAAATC
GCCACCGTGCTGGGGGTCGACGATCCCTGCGCCATCAGTTGCGAACCCTTCATTCAGTGGGTGGTCGAAGATCACTTTGT
CGCCGGGCGACCCGCCTGGGAGACGGCGGGCGTGCAGATGACCGATGACGTGTTGCCCTGGGAGCAAATGAAGCTGCGGA
TGCTCAACGGCAGCCACTCTTTCCTCGCCTGGCTTGGCTATCTGGCAGGGCATGCGCACATTAGCGACTGCATGCGGGAT
GAGGTCTTCCGCCGCGCCGCCCGCCAGCTGATGCTTGACGAACAGGCTCCGACGCTGACCATTACCGGCGTTGATCTGCT
GGCCTATGCCGACAGTCTCATCGCCCGCTTCAGCAATCCGGCGCTCAAACACCGCACCTGGCAAATCGCCATGGACGGTA
GCCAGAAGCTGCCCCAGCGCATGCTCGATGGCATCCGCGTACATCTGGCGCGCGACAGCCGTTGGCCGCTGCTGGCTCTC
GGCGTGGCCGGCTGGATGCGCTACGTCAGCGGCACGGACGACGCCGGTCAGACGATCGACGTGCGCGATCCGCTGGTCGA
CAAGATCCGGCAGCGGGTGGCCCAGAGCGATGAGCAGCAGCGCGTCGACGCCCTGCTGGGGCTGGAGGAAATATTTGGCC
GCGACCTGCCGCACAACGCCCAGTTTGTCGCCGGGATCCGCGCCGCCTGGCAACAGCTGGCGACGCACGGCGCCCGCGAG
GCCGTCGCCCGCGCGCTGAATTCTTAA

Upstream 100 bases:

>100_bases
AGCTCACAGTCAGCGGATAATTTCGGCTTACCAATTTAACTTCCTGTCATATAACTTTAGACTGGCATTGTTAATAAGCA
GTTAAACAGGTGTGGGAAGA

Downstream 100 bases:

>100_bases
CAATATTTGCGCTTATGCGGACAGAATTCTCTTCTGTCCGCCTCAGGACTTCTCTTTTCCCCCTTTTTTCGTCAGGATAG
GCGTAACTGTTACAACATTA

Product: putative mannitol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEISLFSGDTLMSQLREQDHLFT
VLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQS
APGILVEALARRRERGLPPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEI
ATVLGVDDPCAISCEPFIQWVVEDHFVAGRPAWETAGVQMTDDVLPWEQMKLRMLNGSHSFLAWLGYLAGHAHISDCMRD
EVFRRAARQLMLDEQAPTLTITGVDLLAYADSLIARFSNPALKHRTWQIAMDGSQKLPQRMLDGIRVHLARDSRWPLLAL
GVAGWMRYVSGTDDAGQTIDVRDPLVDKIRQRVAQSDEQQRVDALLGLEEIFGRDLPHNAQFVAGIRAAWQQLATHGARE
AVARALNS

Sequences:

>Translated_488_residues
MTTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEISLFSGDTLMSQLREQDHLFT
VLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQS
APGILVEALARRRERGLPPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEI
ATVLGVDDPCAISCEPFIQWVVEDHFVAGRPAWETAGVQMTDDVLPWEQMKLRMLNGSHSFLAWLGYLAGHAHISDCMRD
EVFRRAARQLMLDEQAPTLTITGVDLLAYADSLIARFSNPALKHRTWQIAMDGSQKLPQRMLDGIRVHLARDSRWPLLAL
GVAGWMRYVSGTDDAGQTIDVRDPLVDKIRQRVAQSDEQQRVDALLGLEEIFGRDLPHNAQFVAGIRAAWQQLATHGARE
AVARALNS
>Mature_487_residues
TTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEISLFSGDTLMSQLREQDHLFTV
LEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQSA
PGILVEALARRRERGLPPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEIA
TVLGVDDPCAISCEPFIQWVVEDHFVAGRPAWETAGVQMTDDVLPWEQMKLRMLNGSHSFLAWLGYLAGHAHISDCMRDE
VFRRAARQLMLDEQAPTLTITGVDLLAYADSLIARFSNPALKHRTWQIAMDGSQKLPQRMLDGIRVHLARDSRWPLLALG
VAGWMRYVSGTDDAGQTIDVRDPLVDKIRQRVAQSDEQQRVDALLGLEEIFGRDLPHNAQFVAGIRAAWQQLATHGAREA
VARALNS

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family. UxuB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=487, Percent_Identity=78.6447638603696, Blast_Score=796, Evalue=0.0,
Organism=Escherichia coli, GI1790779, Length=486, Percent_Identity=58.4362139917695, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI1787823, Length=470, Percent_Identity=56.5957446808511, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI48994885, Length=504, Percent_Identity=23.2142857142857, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1790028, Length=270, Percent_Identity=26.2962962962963, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6324401, Length=486, Percent_Identity=38.477366255144, Blast_Score=349, Evalue=4e-97,
Organism=Saccharomyces cerevisiae, GI6320765, Length=486, Percent_Identity=38.477366255144, Blast_Score=349, Evalue=4e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 53847; Mature: 53716

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEI
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SLFSGDTLMSQLREQDHLFTVLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQV
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQSAPGILVEALARRRERGLPPF
EEEEEEEECCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEI
EEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHH
ATVLGVDDPCAISCEPFIQWVVEDHFVAGRPAWETAGVQMTDDVLPWEQMKLRMLNGSHS
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCHH
FLAWLGYLAGHAHISDCMRDEVFRRAARQLMLDEQAPTLTITGVDLLAYADSLIARFSNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCC
ALKHRTWQIAMDGSQKLPQRMLDGIRVHLARDSRWPLLALGVAGWMRYVSGTDDAGQTID
HHHCEEEEEEECCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VRDPLVDKIRQRVAQSDEQQRVDALLGLEEIFGRDLPHNAQFVAGIRAAWQQLATHGARE
CCCHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVARALNS
HHHHHHCC
>Mature Secondary Structure 
TTIATATLPKNVQYPQYDRSQLRSRIVHFGFGAFHRAHQALLTDRVLNNVGGDWGICEI
CCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
SLFSGDTLMSQLREQDHLFTVLEKGADGNQPIVIGAVHECLNARLDSLAAIIEKFCEPQV
EEECCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCE
AIVSLTITEKGYCIDPATGKLDPTHPRIIHDLENPTLPQSAPGILVEALARRRERGLPPF
EEEEEEEECCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCE
TVLSCDNIPDNGHVVKNAVLGMAEKRSPALADWIADNVSFPGTMVDRIVPAATPESLAEI
EEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHH
ATVLGVDDPCAISCEPFIQWVVEDHFVAGRPAWETAGVQMTDDVLPWEQMKLRMLNGSHS
HHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCHH
FLAWLGYLAGHAHISDCMRDEVFRRAARQLMLDEQAPTLTITGVDLLAYADSLIARFSNP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCC
ALKHRTWQIAMDGSQKLPQRMLDGIRVHLARDSRWPLLALGVAGWMRYVSGTDDAGQTID
HHHCEEEEEEECCHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
VRDPLVDKIRQRVAQSDEQQRVDALLGLEEIFGRDLPHNAQFVAGIRAAWQQLATHGARE
CCCHHHHHHHHHHHCCHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVARALNS
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]