| Definition | Klebsiella pneumoniae subsp. pneumoniae MGH 78578 chromosome, complete genome. |
|---|---|
| Accession | NC_009648 |
| Length | 5,315,120 |
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The map label for this gene is ade [H]
Identifier: 152971093
GI number: 152971093
Start: 2799422
End: 2801233
Strand: Direct
Name: ade [H]
Synonym: KPN_02554
Alternate gene names: 152971093
Gene position: 2799422-2801233 (Clockwise)
Preceding gene: 152971091
Following gene: 152971094
Centisome position: 52.67
GC content: 65.89
Gene sequence:
>1812_bases ATGTCCAGCAATGCTCAAGTCCGCCGTCGCGCCGTGCAGGCCGCGCGCGGTGAATCCCCGTTTGATCTGCTGCTGATCGA TGCGCAGATCGTCGATATGGCCACGGGCGAAATTCGCCCCGCTGACGTCGGTATCGTCGGCGAGATGATCGCCAGCGTCC ATCCGCGCGGCAGTCGCGAAGACGCCCATGAAGTGCGTTCCCTGGCCGGTGGCTACCTGTCCCCCGGCCTGATGGACACC CACGTGCATCTCGAAAGCTCACACCTGCCGCCAGAGCGCTATGCGGAAATCGTCCTCACCCAGGGCACCACCGCGGTGTT CTGGGATCCGCATGAGCTGGCCAACGTCCTCGGCGTCGCTGGCGTGCGCTATGCGGTGGACGCCAGCCGCCATCTGCCGC TGCAGGTGATGGTCGCCGCCCCGTCCAGCGTCCCCTCCACGCCGGGTCTCGAAATGTCCGGCGCTGATTTCGCCGGCGCG GAGATGGAGACCATGCTCGGCTGGCCGGAAGTGCGCGGCGTGGCGGAGGTGATGGATATGCACGGCGTGCTGCACGGTAG CGAGCGGATGCAGGAGATTGTCCAGGCCGGTCTCAACAGCGGCAAACTGATTGAAGGCCACGCCCGCGGCCTGAGCGGCG CTGACCTGCAGGCCTACCTCGCCGCCGGCGTCACCTCCGATCACGAACTGACCTCGGCGGACGACGCGCTGGAAAAACTG CGCGCCGGGCTGACGATCGAGATCCGCGGCTCGCACCCCTATCTGCTGCCGGATATCGTCGCGGCGTTAAAAACGCTGCC GCACCTCTCCTCGCAGATCACCGTCTGCACCGATGACGTGCCGCCGGATATACTACTGGAGAAAGGCGGCATCATCGCCC TGCTTAATCTGCTGATCGAGCACGGTTTACCGGCGGTCGATGCGCTGCGATTCGCCACCCTCAACGCCGCTATTCGCCTG CAGCGCCACGATCTCGGGCTGATTGCCGCCGGGCGGCGCGCCGATCTGGTGGTGTTTGATTCCCTGGAGAAACTGGTGGC CCGCGAAGTCTACATAGGCGGTAAGCTGCTGGCCCGCGCGGGCAACCTGCTGACACCGATCGCGCCCGCCGCGGGCGTCA CGCCGCCGCGCGATACTTTGCAGATCGCCCCCCTCCGCGCCGATGACTTTATTCTGCGCGTCCAGGGCATTCGTCACGGC ATCGCCCGCCTGCGCCATATCCGCGGCGCGCGCTTCACCCAGTGGGGCGAAGTGGAAGTGCAGGTTCGTGACGGGATAGT CCAGCTGCCCGCCGGCTTCAGTCTGATCTGGGTCAAGCACCGCCACGGCCGCCATCAGGCGACGCCGCAAATCGCCCTGC TTGAAGGCTGGGGTGAGCTGCGCGGCGCCATCGCCACCAGCTACTCCCACGACTCGCATAATCTGGTGGTGCTCGGGCGC GACGCTAATGATATGGCGCTGGCGGCCAACCAGCTTATCGCCTCCGGCGGCGGGATGGCGCTGGCGCAACAGGGCGAGAT CCTCGCCCATGTGGCGATGCCGATTGCCGGCATGCTGTCGGATCTCCCGGCCGCGGAACTGGCGCGTCAGTTCCGCGAGC TGCGCGATCTGAGCAGCCAAGTCGCCGACTGGGAGCCGCCGTACCGGGTCTTCAAAGCCATTGAAGGCACCTGCCTTGCC TGTAACGCCGGGCCGCATTTAACCGATTTGGGTCTGACCGACGGCGGCAGCCGCCAGATAGTCGACCCGTTGATAGCCTG CCGGGAGATCCCGGAGCCAACCGATCACAACAATAATCCTCAGGGAGCCTGA
Upstream 100 bases:
>100_bases TGCACAATAACCCGAGCTTATCGGGTGATAAATTTATTCATCTGGGCAAACGTTTGCTGTGCCCCTAGAGTATCCGCATT ATCCTTGTGCCGGAGTGGTT
Downstream 100 bases:
>100_bases GCATGGCCGATAACACACTTCACTCTTCCGCCCGCGCTAACTGGCTGGAGCGCCGCTTTGCGCTGCGCTCGCGCGGCGGC ACGCTACGCACCGAATGCCT
Product: putative amidohydrolase
Products: NA
Alternate protein names: Adenase; Adenine aminase [H]
Number of amino acids: Translated: 603; Mature: 602
Protein sequence:
>603_residues MSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDT HVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGA EMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKL RAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAVDALRFATLNAAIRL QRHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHG IARLRHIRGARFTQWGEVEVQVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGR DANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEPPYRVFKAIEGTCLA CNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA
Sequences:
>Translated_603_residues MSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDT HVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGA EMETMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKL RAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAVDALRFATLNAAIRL QRHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHG IARLRHIRGARFTQWGEVEVQVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGR DANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEPPYRVFKAIEGTCLA CNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA >Mature_602_residues SSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSREDAHEVRSLAGGYLSPGLMDTH VHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVAGVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGAE METMLGWPEVRGVAEVMDMHGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKLR AGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIEHGLPAVDALRFATLNAAIRLQ RHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARAGNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGI ARLRHIRGARFTQWGEVEVQVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGRD ANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQVADWEPPYRVFKAIEGTCLAC NAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNPQGA
Specific function: Unknown
COG id: COG1001
COG function: function code F; Adenine deaminase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the adenine deaminase family [H]
Homologues:
Organism=Escherichia coli, GI1790098, Length=576, Percent_Identity=31.9444444444444, Blast_Score=236, Evalue=2e-63,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006679 - InterPro: IPR006680 - InterPro: IPR011059 [H]
Pfam domain/function: PF01979 Amidohydro_1 [H]
EC number: =3.5.4.2 [H]
Molecular weight: Translated: 64507; Mature: 64375
Theoretical pI: Translated: 5.89; Mature: 5.89
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSRE CCCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCH DAHEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVA HHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHEEEEECCCEEEEECHHHHHHHHHHC GVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGAEMETMLGWPEVRGVAEVMDM CHHEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH HGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKL HHHHCCHHHHHHHHHHCCCCCCEEEHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHH RAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIE HCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHH HGLPAVDALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARA CCCCHHHHHHHHHHHHHEEEEECCCCEEECCCCCCEEEHHHHHHHHHHHHHCCCHHHHHC GNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGIARLRHIRGARFTQWGEVEV CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEE QVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGR EEECCEEECCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEEC DANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQ CCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH VADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNP HCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC QGA CCC >Mature Secondary Structure SSNAQVRRRAVQAARGESPFDLLLIDAQIVDMATGEIRPADVGIVGEMIASVHPRGSRE CCCHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCH DAHEVRSLAGGYLSPGLMDTHVHLESSHLPPERYAEIVLTQGTTAVFWDPHELANVLGVA HHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHEEEEECCCEEEEECHHHHHHHHHHC GVRYAVDASRHLPLQVMVAAPSSVPSTPGLEMSGADFAGAEMETMLGWPEVRGVAEVMDM CHHEEECCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHH HGVLHGSERMQEIVQAGLNSGKLIEGHARGLSGADLQAYLAAGVTSDHELTSADDALEKL HHHHCCHHHHHHHHHHCCCCCCEEEHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHH RAGLTIEIRGSHPYLLPDIVAALKTLPHLSSQITVCTDDVPPDILLEKGGIIALLNLLIE HCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCHHHHHHHHHH HGLPAVDALRFATLNAAIRLQRHDLGLIAAGRRADLVVFDSLEKLVAREVYIGGKLLARA CCCCHHHHHHHHHHHHHEEEEECCCCEEECCCCCCEEEHHHHHHHHHHHHHCCCHHHHHC GNLLTPIAPAAGVTPPRDTLQIAPLRADDFILRVQGIRHGIARLRHIRGARFTQWGEVEV CCCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEE QVRDGIVQLPAGFSLIWVKHRHGRHQATPQIALLEGWGELRGAIATSYSHDSHNLVVLGR EEECCEEECCCCCEEEEEEECCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCEEEEEC DANDMALAANQLIASGGGMALAQQGEILAHVAMPIAGMLSDLPAAELARQFRELRDLSSQ CCCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH VADWEPPYRVFKAIEGTCLACNAGPHLTDLGLTDGGSRQIVDPLIACREIPEPTDHNNNP HCCCCCHHHHHHHCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC QGA CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA