Click here to switch to the map view.

The map label for this gene is lsrR [H]

Identifier: 152971083

GI number: 152971083

Start: 2788853

End: 2789794

Strand: Direct

Name: lsrR [H]

Synonym: KPN_02544

Alternate gene names: 152971083

Gene position: 2788853-2789794 (Clockwise)

Preceding gene: 152971072

Following gene: 152971085

Centisome position: 52.47

GC content: 57.22

Gene sequence:

>942_bases
ATGAGTAAAGAAGACGATATCCGGTTGGATCAGAAGGTGCGTGCCGCATGGATGTACTACATCGCCGGCCAGAATCAGAG
CGAGATTGCCAGCCAGCTGGGCACCTCCAGACCGGTGGTGCAACGGCTGATCGCCGCCGCGAAAGAAGAAGGGATTGTGT
CAATTAATCTGCACCATCCGGTAGCGAACTGCCTCGATTATGCGCAGTTGCTGCAGGAAAAATACCGCTTGATCGAGTGC
AATGTGGTCCCCGCCTTTAGCGAAGAAAGCACCCTCGACAGTGTGTCATTTGGCTGCTATCAGCTGATGGCTCGCTATCT
GCAGGATGATAAAGAGAAAATCATCGGTCTGGGCTCGGGCCTGACCCTGAAAAAAGCGCTGCAGCGCATCGATTTTGACA
GCCTGAATACCCGCTGCGTGGCGCTGATCAGCGCCATGAACGCCGACGGGCAGTGCAATTATTACGATGACGTGCCCCTG
CTGCTGACCCGCAAAATTAAGGCCAAGTACTATCAGTGGCCGGCGCCGCGCTACGCCCAAAGCGCGGATGAGTATGAAAT
GTGGTGCACCAATCGCTTATTCCGCAGCGTCTCCGGCGTCGCCCGCGAGGCGGACGTGATTTTTGTCGGCATTGGTCCGC
TGGGCACGCAAAGTCCGATCTTTAAAGATGGCTTTATCAATCAGGCGCAGATGGATGAGCTGACCGCCCGCGGCGGCATC
GGGGAGATCCTCGGGCGGTTTATTGATGCGCAAGGCGACGTGGTAGACAGCGAGATCAACCGCATGATCACCAGCTATGA
TATCCGCCAGAGCCACTGCCCGCGGATTGCCGCTGCCTGTGGAGAACATAAACGACCGGCGATCCTGGCCGCCCTTAAAG
GCGGCTGGATCAATGGCCTGGTGACCGATGAGCATACCGCCCGCTGGCTGCTGACGCGGTAA

Upstream 100 bases:

>100_bases
GAAAAGAGCAAAAGCTTGCCAGTTATGCCAACCACGGCGAGAATGCGGGTATTCGCCGGGCCAATTGCGTGCCCTGGCCA
GCAACTTAGGGCGGGAAACC

Downstream 100 bases:

>100_bases
CGTTTAACAGCCAGACAGCGACTCAGCTGCTGCTCATCAGTCGCGGGGGAATTTCAATCCGCTGCTGGCTGGCTTCGCCG
GCGTCAATAATCGAAAAAAC

Product: SorC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSKEDDIRLDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSINLHHPVANCLDYAQLLQEKYRLIEC
NVVPAFSEESTLDSVSFGCYQLMARYLQDDKEKIIGLGSGLTLKKALQRIDFDSLNTRCVALISAMNADGQCNYYDDVPL
LLTRKIKAKYYQWPAPRYAQSADEYEMWCTNRLFRSVSGVAREADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGI
GEILGRFIDAQGDVVDSEINRMITSYDIRQSHCPRIAAACGEHKRPAILAALKGGWINGLVTDEHTARWLLTR

Sequences:

>Translated_313_residues
MSKEDDIRLDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSINLHHPVANCLDYAQLLQEKYRLIEC
NVVPAFSEESTLDSVSFGCYQLMARYLQDDKEKIIGLGSGLTLKKALQRIDFDSLNTRCVALISAMNADGQCNYYDDVPL
LLTRKIKAKYYQWPAPRYAQSADEYEMWCTNRLFRSVSGVAREADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGI
GEILGRFIDAQGDVVDSEINRMITSYDIRQSHCPRIAAACGEHKRPAILAALKGGWINGLVTDEHTARWLLTR
>Mature_312_residues
SKEDDIRLDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSINLHHPVANCLDYAQLLQEKYRLIECN
VVPAFSEESTLDSVSFGCYQLMARYLQDDKEKIIGLGSGLTLKKALQRIDFDSLNTRCVALISAMNADGQCNYYDDVPLL
LTRKIKAKYYQWPAPRYAQSADEYEMWCTNRLFRSVSGVAREADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGIG
EILGRFIDAQGDVVDSEINRMITSYDIRQSHCPRIAAACGEHKRPAILAALKGGWINGLVTDEHTARWLLTR

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=313, Percent_Identity=31.629392971246, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI87082414, Length=310, Percent_Identity=25.4838709677419, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35018; Mature: 34887

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEDDIRLDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSINLHHP
CCCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCH
VANCLDYAQLLQEKYRLIECNVVPAFSEESTLDSVSFGCYQLMARYLQDDKEKIIGLGSG
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHEECCCC
LTLKKALQRIDFDSLNTRCVALISAMNADGQCNYYDDVPLLLTRKIKAKYYQWPAPRYAQ
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHC
SADEYEMWCTNRLFRSVSGVAREADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCH
GEILGRFIDAQGDVVDSEINRMITSYDIRQSHCPRIAAACGEHKRPAILAALKGGWINGL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEECCCCEECE
VTDEHTARWLLTR
ECCCCCCCEEECC
>Mature Secondary Structure 
SKEDDIRLDQKVRAAWMYYIAGQNQSEIASQLGTSRPVVQRLIAAAKEEGIVSINLHHP
CCCCCCCHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEECCH
VANCLDYAQLLQEKYRLIECNVVPAFSEESTLDSVSFGCYQLMARYLQDDKEKIIGLGSG
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHEECCCC
LTLKKALQRIDFDSLNTRCVALISAMNADGQCNYYDDVPLLLTRKIKAKYYQWPAPRYAQ
CHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHC
SADEYEMWCTNRLFRSVSGVAREADVIFVGIGPLGTQSPIFKDGFINQAQMDELTARGGI
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCH
GEILGRFIDAQGDVVDSEINRMITSYDIRQSHCPRIAAACGEHKRPAILAALKGGWINGL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEEEEEECCCCEECE
VTDEHTARWLLTR
ECCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA