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The map label for this gene is baeR [H]

Identifier: 152971070

GI number: 152971070

Start: 2773216

End: 2773938

Strand: Direct

Name: baeR [H]

Synonym: KPN_02531

Alternate gene names: 152971070

Gene position: 2773216-2773938 (Clockwise)

Preceding gene: 152971069

Following gene: 152971071

Centisome position: 52.18

GC content: 61.0

Gene sequence:

>723_bases
ATGACTGAATTGCCTGTAGATGAAAACACCCCACGCATCCTTATCGTGGAAGATGAACCGAAGCTCGGCCAACTGCTGAT
TGATTATCTGCAGGCCGCCGGCTATGCGCCTGCGTTGATTAACCACGGCGACAAGGTCCTGCCCTACGTCCGCCAGACGC
CGCCGCACCTGATCCTGCTGGATCTGATGCTGCCCGGTACCGACGGTCTGACGCTGTGCCGGGAAATTCGCCGCTTCTCC
GATGTTCCGGTGGTGATGGTGACGGCGAAAATCGAAGAGATCGACCGTTTGCTGGGGCTGGAAATAGGCGCCGACGACTA
TATCTGCAAGCCCTACAGCCCGCGGGAAGTGGTCGCCCGGGTAAAAACCATCCTCCGCCGCTGCAAGCCGCAGCGCGATC
TGCAGGCGCTGGACGCCCGGAGCCCGCTGATTGTCGACGAAAGTCGTTTTCAGGCCTCCTGGCGCGACAAGCTGCTGGAC
CTCACTCCCGCCGAGTTCCGGCTGCTGAAAACCCTCTCCCAGGAGCCGGGCAAAGTGTTCTCCCGCGAACAGCTACTCAA
CCATCTGTATGACGATTATCGGGTAGTCACCGATCGCACCATCGACAGCCACATCAAGAACCTGCGGCGCAAGCTGGAGG
CGCTGGACGCCGAGCAGTCGTTTATCCGCGCGGTGTATGGCGTTGGCTACCGCTGGGAAGCGGACGCCTGCCGGCTGGCG
TAG

Upstream 100 bases:

>100_bases
TAGCGGCCCACGGCGGCACCCTGCGTGCCGACCATTCGCCTTTTGGCGGGGTTAGCATTAAAGTTGAGTTACCTCTGGAA
CATGATTTACCGAGAGACGT

Downstream 100 bases:

>100_bases
TTAGCCTTTTCCCGGCTCGCGCTGCGCTTCGCCGGGCTACACGTTCACCGCCATCTGCAATCCGTAGCCCGGGTAAGGCG
TTTACGCCGCAACCCGGGGA

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFS
DVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDARSPLIVDESRFQASWRDKLLD
LTPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA

Sequences:

>Translated_240_residues
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFS
DVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDARSPLIVDESRFQASWRDKLLD
LTPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
>Mature_239_residues
TELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILLDLMLPGTDGLTLCREIRRFSD
VPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRDLQALDARSPLIVDESRFQASWRDKLLDL
TPAEFRLLKTLSQEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=91.25, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=44, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.1785714285714, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=36.5957446808511, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.3333333333333, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=32.1888412017167, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=33.6363636363636, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=34.0909090909091, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=33.9285714285714, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=33.6283185840708, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=31.140350877193, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.4932735426009, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27519; Mature: 27388

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRDLQALDARSPLIVDESRFQASWRDKLLDLTPAEFRLLKTLSQEPGKVF
HHHHHHHCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCC
>Mature Secondary Structure 
TELPVDENTPRILIVEDEPKLGQLLIDYLQAAGYAPALINHGDKVLPYVRQTPPHLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDVPVVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRDLQALDARSPLIVDESRFQASWRDKLLDLTPAEFRLLKTLSQEPGKVF
HHHHHHHCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDAEQSFIRAVYGVGYRWEADACRLA
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]