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The map label for this gene is yoaD [H]

Identifier: 152970878

GI number: 152970878

Start: 2552962

End: 2554545

Strand: Direct

Name: yoaD [H]

Synonym: KPN_02331

Alternate gene names: 152970878

Gene position: 2552962-2554545 (Clockwise)

Preceding gene: 152970877

Following gene: 152970880

Centisome position: 48.03

GC content: 58.65

Gene sequence:

>1584_bases
ATGCAGACTGCACAAAAAGTCATTACGGCCTATCGTCACAAACGCATTATTGTCTGCCTGCTGGTAGCCCTGGCGACCCT
GGGCGCCACATTAGCCATCCGATTTATTTCGCAGCGCAGCGTAAATGAAGATTATATTCGCACGGCCGCCAGCCAACGGG
TGGCGGCGCTCAATGACATCTTGCGCCCGCTAAGCGCGCAGCGAGCCACCCTGCTCCCTCTGGTGGGCAAACCCTGCCCT
GATATCCATCTGACGCTGCGCAAAATGGCGGCCTCGTTGCAAACCATTCGTTCCGTCGCCCTCGTCACGTCAGGTATCGT
TTACTGTTCCAGTATTTTTGGCCCGCGACAGGCAGACTTACATCGCCTGCAGCCCGCGCTTCCTGCGCCCCGCCCTCTGC
TGCTCTTCTCGAACGACAGCTCCTTGCTCAAAGGCTCGCCGGTACTGATCCAATGGTATCCAGCCGCGGAGAACGGCCTG
GACGGCGTGATGCTGGTGGTGAATATTGAGCTGCTGGGAACCTTAATTCTTAATGAAAAATCGGCCCTGATCAGCGACGT
CAGCCTGCAGGTTGGCGATCGTTATTTTAGCAGCCGCCATGGGCTTCTCGAAAAAGCGCATGTCCCGCAGGGCACGGTGA
TTTATCGCCAGCGCTCTACGGAGTTTCCGTTTACTGTCAATATTAACGGCCCTGGCGCCTCGGCGATTGCGCTTGAGGAG
CTGCCCGGCGAGCTGCCGCTGGCGCTGATTTTTAGCCTGCTAATGACCGGCATCGCCTGGCTGGCCACCGCCGGCAGAAT
GAGTTTCTCGCGGGAAATAAGCCTTGGCATTTCGGCCCGGGAGTTTGCCCTCTGGTGCCAGCCGCTGCAGGATGCGCGCA
GCGGCCGCTGCTGCGGGGTGGAGATCCTGCTGCGCTGGAATAATCCCCGCCGTGGGACGATTTCGCCGGAGGTATTTATC
CCCATCGCCGAAGGCAATAATCTGATCATCCCTCTCACCCGCTATGTGATTGCCGAAACCGCTCGCCGCCTGGACGCTTT
TCCTCGCGACCGCCATTTTCACATCGCGATCAATGTCGCCGCGCGCCATTTCGCTAACGGACTCCTGCTGCGCGACCTGC
ACAATTACTGGTTCAGCGTGGATCCGGTGCAGCAGCTGGTGGTCGAGCTAACCGAACGCGATGTCCTGCAGGATGGCGAC
CAGCATATGGCCGAACATCTGCACTTTAAAGGCGTACAGCTGGCGATCGATGATTTTGGTACCGGCAATACTTCGCTCTC
ATGGCTGGAAAAGCTGCGCCCGGACGTCCTGAAGATCGACCGCTCGTTCACCAGCTCGGTCGGCATAGATAGCGTGAACG
CGACGGTGACAGATATTATTATCGCCCTCGCCAACCGCCTGCATATTGTTACCGTTGCCGAAGGGGTGGAGACGCTGGAG
CAGGAAAACTACCTGCGTAGCCACGGCGTCGATGTGCTGCAGGGGTTTTATTATGCGCGGCCGATGCCGGTGGAGGCGTT
CCCGGCGTGGCTGGCCAGCAGGGAGGAGAGTGAGAGTGAGGGTGAGAGCGAGACGACAGAATAA

Upstream 100 bases:

>100_bases
CGCATTTTCTTTTTTCTATACCTGGCGATATTCTGCCACTACACTTGCTCTATCAAATAAGCCACGCTTAACCACTCGTC
CTGTCGACAGGGTGTCGCAC

Downstream 100 bases:

>100_bases
CTCGCCGGCCGCAGCGGCCGGCGAGCCTGGCGATTACTCTTCTTCGTCGCTCGGCGGCCGAGTGACCACCGCGCGCACCA
GATCGACCCGGTAATCATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MQTAQKVITAYRHKRIIVCLLVALATLGATLAIRFISQRSVNEDYIRTAASQRVAALNDILRPLSAQRATLLPLVGKPCP
DIHLTLRKMAASLQTIRSVALVTSGIVYCSSIFGPRQADLHRLQPALPAPRPLLLFSNDSSLLKGSPVLIQWYPAAENGL
DGVMLVVNIELLGTLILNEKSALISDVSLQVGDRYFSSRHGLLEKAHVPQGTVIYRQRSTEFPFTVNINGPGASAIALEE
LPGELPLALIFSLLMTGIAWLATAGRMSFSREISLGISAREFALWCQPLQDARSGRCCGVEILLRWNNPRRGTISPEVFI
PIAEGNNLIIPLTRYVIAETARRLDAFPRDRHFHIAINVAARHFANGLLLRDLHNYWFSVDPVQQLVVELTERDVLQDGD
QHMAEHLHFKGVQLAIDDFGTGNTSLSWLEKLRPDVLKIDRSFTSSVGIDSVNATVTDIIIALANRLHIVTVAEGVETLE
QENYLRSHGVDVLQGFYYARPMPVEAFPAWLASREESESEGESETTE

Sequences:

>Translated_527_residues
MQTAQKVITAYRHKRIIVCLLVALATLGATLAIRFISQRSVNEDYIRTAASQRVAALNDILRPLSAQRATLLPLVGKPCP
DIHLTLRKMAASLQTIRSVALVTSGIVYCSSIFGPRQADLHRLQPALPAPRPLLLFSNDSSLLKGSPVLIQWYPAAENGL
DGVMLVVNIELLGTLILNEKSALISDVSLQVGDRYFSSRHGLLEKAHVPQGTVIYRQRSTEFPFTVNINGPGASAIALEE
LPGELPLALIFSLLMTGIAWLATAGRMSFSREISLGISAREFALWCQPLQDARSGRCCGVEILLRWNNPRRGTISPEVFI
PIAEGNNLIIPLTRYVIAETARRLDAFPRDRHFHIAINVAARHFANGLLLRDLHNYWFSVDPVQQLVVELTERDVLQDGD
QHMAEHLHFKGVQLAIDDFGTGNTSLSWLEKLRPDVLKIDRSFTSSVGIDSVNATVTDIIIALANRLHIVTVAEGVETLE
QENYLRSHGVDVLQGFYYARPMPVEAFPAWLASREESESEGESETTE
>Mature_527_residues
MQTAQKVITAYRHKRIIVCLLVALATLGATLAIRFISQRSVNEDYIRTAASQRVAALNDILRPLSAQRATLLPLVGKPCP
DIHLTLRKMAASLQTIRSVALVTSGIVYCSSIFGPRQADLHRLQPALPAPRPLLLFSNDSSLLKGSPVLIQWYPAAENGL
DGVMLVVNIELLGTLILNEKSALISDVSLQVGDRYFSSRHGLLEKAHVPQGTVIYRQRSTEFPFTVNINGPGASAIALEE
LPGELPLALIFSLLMTGIAWLATAGRMSFSREISLGISAREFALWCQPLQDARSGRCCGVEILLRWNNPRRGTISPEVFI
PIAEGNNLIIPLTRYVIAETARRLDAFPRDRHFHIAINVAARHFANGLLLRDLHNYWFSVDPVQQLVVELTERDVLQDGD
QHMAEHLHFKGVQLAIDDFGTGNTSLSWLEKLRPDVLKIDRSFTSSVGIDSVNATVTDIIIALANRLHIVTVAEGVETLE
QENYLRSHGVDVLQGFYYARPMPVEAFPAWLASREESESEGESETTE

Specific function: May serve as a negative regulator of cellulose synthesis (as has been suggested for S.typhimurium); over-expression inhibits cell aggregation in strains able to produce adhesive curli fimbriae. Cyclic-di-GMP is a second messenger which controls cell surfa

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI87081980, Length=526, Percent_Identity=55.5133079847909, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1788502, Length=522, Percent_Identity=29.1187739463602, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87081845, Length=504, Percent_Identity=30.1587301587302, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=36.25, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=35.2, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081921, Length=257, Percent_Identity=34.2412451361868, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081743, Length=271, Percent_Identity=33.5793357933579, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1787541, Length=224, Percent_Identity=33.9285714285714, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI226510982, Length=254, Percent_Identity=31.1023622047244, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787055, Length=265, Percent_Identity=30.9433962264151, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788849, Length=251, Percent_Identity=29.4820717131474, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI87082096, Length=206, Percent_Identity=29.6116504854369, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787410, Length=119, Percent_Identity=31.0924369747899, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 58299; Mature: 58299

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAQKVITAYRHKRIIVCLLVALATLGATLAIRFISQRSVNEDYIRTAASQRVAALNDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LRPLSAQRATLLPLVGKPCPDIHLTLRKMAASLQTIRSVALVTSGIVYCSSIFGPRQADL
HHHHCCCCCEECHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
HRLQPALPAPRPLLLFSNDSSLLKGSPVLIQWYPAAENGLDGVMLVVNIELLGTLILNEK
HHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHHCCCC
SALISDVSLQVGDRYFSSRHGLLEKAHVPQGTVIYRQRSTEFPFTVNINGPGASAIALEE
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEHHH
LPGELPLALIFSLLMTGIAWLATAGRMSFSREISLGISAREFALWCQPLQDARSGRCCGV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEE
EILLRWNNPRRGTISPEVFIPIAEGNNLIIPLTRYVIAETARRLDAFPRDRHFHIAINVA
EEEEEECCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEHH
ARHFANGLLLRDLHNYWFSVDPVQQLVVELTERDVLQDGDQHMAEHLHFKGVQLAIDDFG
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCC
TGNTSLSWLEKLRPDVLKIDRSFTSSVGIDSVNATVTDIIIALANRLHIVTVAEGVETLE
CCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHH
QENYLRSHGVDVLQGFYYARPMPVEAFPAWLASREESESEGESETTE
HHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTAQKVITAYRHKRIIVCLLVALATLGATLAIRFISQRSVNEDYIRTAASQRVAALNDI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LRPLSAQRATLLPLVGKPCPDIHLTLRKMAASLQTIRSVALVTSGIVYCSSIFGPRQADL
HHHHCCCCCEECHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
HRLQPALPAPRPLLLFSNDSSLLKGSPVLIQWYPAAENGLDGVMLVVNIELLGTLILNEK
HHHCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEEEEHHHHHHHHCCCC
SALISDVSLQVGDRYFSSRHGLLEKAHVPQGTVIYRQRSTEFPFTVNINGPGASAIALEE
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEECCCCCCEEEEECCCCCCEEEHHH
LPGELPLALIFSLLMTGIAWLATAGRMSFSREISLGISAREFALWCQPLQDARSGRCCGV
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCCEEE
EILLRWNNPRRGTISPEVFIPIAEGNNLIIPLTRYVIAETARRLDAFPRDRHFHIAINVA
EEEEEECCCCCCCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEEEEEHH
ARHFANGLLLRDLHNYWFSVDPVQQLVVELTERDVLQDGDQHMAEHLHFKGVQLAIDDFG
HHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCC
TGNTSLSWLEKLRPDVLKIDRSFTSSVGIDSVNATVTDIIIALANRLHIVTVAEGVETLE
CCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCEEEEEEHHHHHHHH
QENYLRSHGVDVLQGFYYARPMPVEAFPAWLASREESESEGESETTE
HHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]