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The map label for this gene is pabB [H]

Identifier: 152970875

GI number: 152970875

Start: 2549315

End: 2550670

Strand: Direct

Name: pabB [H]

Synonym: KPN_02328

Alternate gene names: 152970875

Gene position: 2549315-2550670 (Clockwise)

Preceding gene: 152970873

Following gene: 152970876

Centisome position: 47.96

GC content: 61.8

Gene sequence:

>1356_bases
ATGTTGTCCCCCGCGATTATTACCCTGCCCTGGCGCCCGGATGCGGCCGAACACTATTTTGCGCCGTTAAGCGCCCTGCC
CTGGGCGATGCTGCTGCATTCCGGCTTTGCCGACCATCCGCATAACCGCTTTGATATTCTGGTGGCTGCCCCGCGCGCCA
CGCTGCTGACGCGCGGTGAACAGACGTGGGTCGACGACGGCGAAACCGTTGTTGTCTCAGCGGAAGATCCGCTGCAGCTC
CTGCAGCAGCAGTTGGATCGTCAGCCGTTCACGCCGCAACCCCATGACGATCTGCCGTTTCTCGGCGGCGCGCTGGGATT
ATTCGGTTACGACCTGGGCCGTCGCTTTGAGCGTCTCCCTTCGCACGCGCAGGCCGATATCGCGCTGGCGGATATGGCGG
TGGGGATCTATGACTGGGCGCTTATCGTCGACCACCAGCGCCAACAGATATCGCTGCTCAGCTATGACGACCCGCAGCAG
CGTCTACAGTGGCTGGAGGCGCAAACGCCGACGCCGGGTGAAACCTTCGCCCTGACCTCTGCCTGGCAGTCAAATATGAG
CCGCCAGCAGTACGGGGAAAAATTTCGCCAGGTACAGGCCTATCTGCACAGCGGCGACTGCTATCAGGTCAACCTCGCCC
AGCGTTTTCAGGCCAGCTACGTCGGTGATGAATGGCAGGCCTTCCGCCAGCTGAACGCCGTCAACCGCGCCCCCTTTAGC
GCCTTTATTCGCCTCGATGAAGGGGCGATTTTTAGCCTGTCGCCGGAGCGCTTTATCCAGCTGCGCCAGGGGGAGATCCA
GACGCGGCCGATAAAAGGCACCCTGCCGCGGCTCGATTCGCCGCTGGCAGATGCGCAGCAGGCTGAGAAGCTGGCGAATT
CGCCGAAAGATCGCGCCGAGAATTTAATGATTGTCGACCTGATGCGCAACGACATCGGCCGCGTCGCCGTCCCGGGCAGC
GTGCGGGTCCCCGAGCTGTTCGTGGTGGAGCCATTCCCGGCGGTCCATCATCTGGTCAGCACCATCACCGCCCGCCTGCC
AATGACGCTGCACGCCAGCGACCTGCTGCGCGCCGCCTTTCCCGGCGGCTCGATCACCGGCGCGCCGAAAGTGCGGGCGA
TGGAGATTATCGATGAACTGGAGCCCCAACGACGCAACGCCTGGTGTGGGAGCATTGGCTACCTGAGCTATTGCGGCAAT
ATGGATACCAGCATCACCATTCGCACCCTGACGGCATGGCAGGGACAGCTGTACTGCTCCGCCGGCGGCGGAATTGTGGC
GGATAGCGAGGAAGCGGCGGAATATCAGGAAACTTTTGATAAAGTTAATCGTATCCTGCAGCAACTGGAGAACTAG

Upstream 100 bases:

>100_bases
ACCTGCAAACATCTTTTACTCCTGCTACATTGTGGGGCGTAATTATTTCACGCCGTCCCCAACTACGCCAGAGGGGCGGT
AACGTTCAGGATCGAGAAAG

Downstream 100 bases:

>100_bases
ACCATGGCGGATCGCGCCCTTAATCTGGATGATTTTCTGTCCCGCTTTCAGCTTCTGCGCCCGCAGCCTTCGCGCCATGC
GCTCAATCAGCGGCAGGCGG

Product: para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTRGEQTWVDDGETVVVSAEDPLQL
LQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDDPQQ
RLQWLEAQTPTPGETFALTSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQASYVGDEWQAFRQLNAVNRAPFS
AFIRLDEGAIFSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDRAENLMIVDLMRNDIGRVAVPGS
VRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSYCGN
MDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN

Sequences:

>Translated_451_residues
MLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTRGEQTWVDDGETVVVSAEDPLQL
LQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDDPQQ
RLQWLEAQTPTPGETFALTSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQASYVGDEWQAFRQLNAVNRAPFS
AFIRLDEGAIFSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDRAENLMIVDLMRNDIGRVAVPGS
VRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSYCGN
MDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN
>Mature_451_residues
MLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTRGEQTWVDDGETVVVSAEDPLQL
LQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLPSHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDDPQQ
RLQWLEAQTPTPGETFALTSAWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQASYVGDEWQAFRQLNAVNRAPFS
AFIRLDEGAIFSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDRAENLMIVDLMRNDIGRVAVPGS
VRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSYCGN
MDTSITIRTLTAWQGQLYCSAGGGIVADSEEAAEYQETFDKVNRILQQLEN

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=450, Percent_Identity=76.6666666666667, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1787518, Length=408, Percent_Identity=31.3725490196078, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1786809, Length=206, Percent_Identity=26.6990291262136, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=444, Percent_Identity=31.0810810810811, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324361, Length=405, Percent_Identity=28.641975308642, Blast_Score=153, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50431; Mature: 50431

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTRGE
CCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCC
QTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLP
CCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDDPQQRLQWLEAQTPTPGETFALTS
CCHHCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEEEHH
AWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQASYVGDEWQAFRQLNAVNRAPFS
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHCCCCCE
AFIRLDEGAIFSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDRAE
EEEEECCCCEEEECHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHC
NLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAF
CEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEECHHHHHHHHC
PGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSYCGNMDTSITIRTLTAWQGQLYCS
CCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHCCCCCCEEEEEEEEECCCEEEEE
AGGGIVADSEEAAEYQETFDKVNRILQQLEN
CCCCEEECCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSPAIITLPWRPDAAEHYFAPLSALPWAMLLHSGFADHPHNRFDILVAAPRATLLTRGE
CCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCC
QTWVDDGETVVVSAEDPLQLLQQQLDRQPFTPQPHDDLPFLGGALGLFGYDLGRRFERLP
CCCCCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
SHAQADIALADMAVGIYDWALIVDHQRQQISLLSYDDPQQRLQWLEAQTPTPGETFALTS
CCHHCCCHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEEEHH
AWQSNMSRQQYGEKFRQVQAYLHSGDCYQVNLAQRFQASYVGDEWQAFRQLNAVNRAPFS
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCHHHHHHHHHHHHCCCCCE
AFIRLDEGAIFSLSPERFIQLRQGEIQTRPIKGTLPRLDSPLADAQQAEKLANSPKDRAE
EEEEECCCCEEEECHHHHHHHHCCCCEECCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHC
NLMIVDLMRNDIGRVAVPGSVRVPELFVVEPFPAVHHLVSTITARLPMTLHASDLLRAAF
CEEEEEEHHCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEECHHHHHHHHC
PGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSYCGNMDTSITIRTLTAWQGQLYCS
CCCCCCCCCCHHHHHHHHHCCCHHHCCCCCCCHHHHHCCCCCCEEEEEEEEECCCEEEEE
AGGGIVADSEEAAEYQETFDKVNRILQQLEN
CCCCEEECCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]