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The map label for this gene is ycgO [H]

Identifier: 152970854

GI number: 152970854

Start: 2528860

End: 2530593

Strand: Direct

Name: ycgO [H]

Synonym: KPN_02307

Alternate gene names: 152970854

Gene position: 2528860-2530593 (Clockwise)

Preceding gene: 152970853

Following gene: 152970857

Centisome position: 47.58

GC content: 63.09

Gene sequence:

>1734_bases
TTGGACGCCGCTGCGGTCATTAGTCTGTTTATTCTGGGTTCTGTTTTAGTAACCTGCAGTATCTTATTGAGCTCCTTTTC
TTCGCGCCTTGGCATCCCGATTCTGGTCATCTTTCTGGCCATCGGGATGCTGGCAGGCATTGACGGCATCGGCGGCATCC
CCTTCGACAACTACCCCTTCGCCTATATGGTGAGTAACCTGGCGCTGGCGGTGATCCTGCTGGATGGCGGGATGCGCACC
CAGGCCAGCTCCTTTCGCGTCGCGCTGTGGCCCGCGCTGTCGCTGGCGACGGTTGGGGTGCTGATCACCTCGGCGCTGAC
CGGGATGATGGCGGCCTGGTTGTTCAAGCTGGATCTGATCGAAGGCCTGCTGATCGGCGCCATTGTCGGCTCCACCGACG
CCGCGGCGGTCTTCTCGCTGCTCGGCGGCAAGGGGCTCAACGAGCGCGTCGGCTCGACGCTGGAGATAGAGTCAGGCAGT
AACGACCCGATGGCGGTCTTCCTGACCATCACCCTGATCGAAATGATCCAGCAGCACCAAACCGGCCTCAGCTGGATGTT
CGCCGTGCATATCATTCAGCAGTTCGGCCTCGGGATCGCCATCGGCCTCGGCGGCGGCTACCTGCTGCTGCAGATGATTA
ACCGCATCGTGCTGCCCGCCGGCCTCTATCCGCTGCTGGCGCTGAGCGGCGGGATCATGATTTTTGCCGTCACCACCTCC
CTCGACGGCAGCGGTATCCTCGCCGTCTATCTCTGCGGCTTTCTGCTGGGCAACCGGCCGATCCGCAACCGGCACGGCAT
CCTGCAGAACTTCGACGGCCTGGCGTGGCTGGCGCAGATCGCCATGTTCCTGGTGCTGGGCCTGCTGGTGACGCCCTCCG
ACCTGCTGCCGATCGCTATCCCGGCGCTGCTGCTGTCGATGTGGATGATATTCATTGCCCGGCCCCTGTCGGTGTTTGCC
GGCCTGCTGCCGTTTCGCGGCTTTAACCTGCGCGAACGGGTGTTTATCAGCTGGGTTGGCCTGCGCGGCGCGGTGCCCAT
TATTCTCGCGGTGTTCCCGATGATGGCCGGCCTGGACAACGCCCGCCTGTTCTTCAATGTCGCCTTCTTCGTGGTGCTGG
TGTCGCTGCTGCTGCAGGGCACTTCGCTGTCGTGGGCGGCGAAAAAAGCCAAAGTGGTGGTTCCGCCCATCAGCTGGCCC
ATCTCCCGCGTCGGGCTGGATATTCACCCGGAAAACCCGTGGGAGCAGTTTGTCTACCAGCTGGGGGCCGATAAGTGGTG
CATCGGCGCGGCGCTGCGCGACTTGCACATGCCACCGGAGACGCGGATTGCCGCGCTGTTTCGCAACAATGTCCTGCTGC
ACCCCACCGGCAGCACCCGCCTGCGGGAAGGCGATATCCTGTGCGTTATTGGTCGAGAGCACGACCTGCCGGCGCTGGGC
AAAATGTTCAGCCAGTCGCCGCCGGTGGCGCTCGATCAGCGCTTTTTCGGCGACTTCATTCTTGATGCTGAGGCCCGCTT
CGCCGATGTGGCGCAAATCTACGGTCTCGACGGCGGTGAGGAGTTCCGCGAGCATCAGCAGTCGCTCGGGGAAGTGGTGC
AGCAGCTGCTGGGCGCGGCGCCGGTGGTGGGCGACCAGGTGGAGTTCGCCGGGATGGTGTGGACGGTAGCTGAAAAAGAG
AACGATCACGTGCTGAAGGTTGGGGTGCGGGTCGCGGAAGACGAGGCGGAGTGA

Upstream 100 bases:

>100_bases
CAGAATAAATTTCCCGAACGCATAGGCGGATCCCCTGCGAATTGTTAAAATAGTGTCACTTTTAGCCATTTTTTCACGCC
AGTCAGGGAGTACGTGAACA

Downstream 100 bases:

>100_bases
TCCGCCCCGGAATAGGTTACAGGGTCACAACTGGCACCCGCGGCGCCAGGGCGCACATCAGCTCATAGCCGACGGTGCCG
CTGCTGGCCGCCACGTCGTC

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWP
ISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKE
NDHVLKVGVRVAEDEAE

Sequences:

>Translated_577_residues
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWP
ISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKE
NDHVLKVGVRVAEDEAE
>Mature_577_residues
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQQHQTGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAIPALLLSMWMIFIARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDNARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWP
ISRVGLDIHPENPWEQFVYQLGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAAPVVGDQVEFAGMVWTVAEKE
NDHVLKVGVRVAEDEAE

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=577, Percent_Identity=88.734835355286, Blast_Score=961, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 62157; Mature: 62157

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AYMVSNLALAVILLDGGMRTQASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLI
HHHHHHHHHEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQQHQ
HHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHH
TGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
CCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEEC
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAI
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PALLLSMWMIFIARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHCCCC
ARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWPISRVGLDIHPENPWEQFVYQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCCCCHHHCCCCCCCCCHHHHHHHH
LGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
HCCCCHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCEECCCEEEEECCCCCCCHHH
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAA
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PVVGDQVEFAGMVWTVAEKENDHVLKVGVRVAEDEAE
CCCCCCCHHCEEEEEEECCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MDAAAVISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGIDGIGGIPFDNYPF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AYMVSNLALAVILLDGGMRTQASSFRVALWPALSLATVGVLITSALTGMMAAWLFKLDLI
HHHHHHHHHEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQQHQ
HHHHHHHHHCCCHHHHHHHHHCCCCCHHHCCCEEEECCCCCCCEEHHHHHHHHHHHHHHH
TGLSWMFAVHIIQQFGLGIAIGLGGGYLLLQMINRIVLPAGLYPLLALSGGIMIFAVTTS
CCHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEEC
LDGSGILAVYLCGFLLGNRPIRNRHGILQNFDGLAWLAQIAMFLVLGLLVTPSDLLPIAI
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
PALLLSMWMIFIARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLDN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHCCCC
ARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPISWPISRVGLDIHPENPWEQFVYQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHCCCEEEECCCCCCHHHCCCCCCCCCHHHHHHHH
LGADKWCIGAALRDLHMPPETRIAALFRNNVLLHPTGSTRLREGDILCVIGREHDLPALG
HCCCCHHHHHHHHHCCCCCHHHHHHHHHCCEEEECCCCCCEECCCEEEEECCCCCCCHHH
KMFSQSPPVALDQRFFGDFILDAEARFADVAQIYGLDGGEEFREHQQSLGEVVQQLLGAA
HHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PVVGDQVEFAGMVWTVAEKENDHVLKVGVRVAEDEAE
CCCCCCCHHCEEEEEEECCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA