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The map label for this gene is lolB [H]

Identifier: 152970783

GI number: 152970783

Start: 2452623

End: 2453234

Strand: Direct

Name: lolB [H]

Synonym: KPN_02236

Alternate gene names: 152970783

Gene position: 2452623-2453234 (Clockwise)

Preceding gene: 152970776

Following gene: 152970784

Centisome position: 46.14

GC content: 60.62

Gene sequence:

>612_bases
ATGAATCGACTGTTCCGCCTGCTGCCGCTGGCCAGCCTCGTCCTCACCGCCTGTTCTCTTCATACGCCGCAAGGGCCTGG
CAAAAGCCCGGATTCGCCGCAGTGGCGTCAGCACCAGCAGGCTGTCCGCAGCCTCAATCAGTTCCAGACCCGCGGGGCGT
TTGCCTATCTTTCCGATGAGCAAAAAGTCTATGCCCGCTTCTTCTGGCAGCAAACCGGCCAGGACCGCTATCGCCTGCTG
CTGACCAACCCGCTGGGCAGCACCGAGCTGTCGCTGACCGCGCAGCCGGGCAGCGTGCAGCTGATCGATAACAAAGGCCA
GACCTATACCGCCGCTGATGCCGAAGAGATGATTGGCCGTCTGACCGGGATGCCGATCCCGTTGAACAGCCTGCGCCAGT
GGATCATCGGCCTGCCGGGCGACGCCACCGACTATTCGCTGGACGATCGGTACCGTCTGCGTGAACTGAACTATACGCAA
AACGGCAAAACCTGGCACGTGACCTACGGCGGCTACACCAGCGATACCCAGCCAGCCCTACCGTCCAATGTCGAGCTGAA
CAATGGCGCTCAGCGCATCAAGCTGAAGATGGATAACTGGATCGTGAAATGA

Upstream 100 bases:

>100_bases
ACGCTAGCATTAAGGGTTATAAATGTAACCTGCTACACAAATCGGCCCGCTGTTCCCTGTCGCCGTTTTTCCCTGTAGAC
ATCAAGGATTTGTCATCATT

Downstream 100 bases:

>100_bases
TGACCCGCTGGCCCTCTCCTGCAAAACTGAATCTGTTTTTATATATCACCGGCCAGCGGGCCGATGGTTACCATACCCTG
CAAACGCTGTTTCAGTTTCT

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDEQKVYARFFWQQTGQDRYRLL
LTNPLGSTELSLTAQPGSVQLIDNKGQTYTAADAEEMIGRLTGMPIPLNSLRQWIIGLPGDATDYSLDDRYRLRELNYTQ
NGKTWHVTYGGYTSDTQPALPSNVELNNGAQRIKLKMDNWIVK

Sequences:

>Translated_203_residues
MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDEQKVYARFFWQQTGQDRYRLL
LTNPLGSTELSLTAQPGSVQLIDNKGQTYTAADAEEMIGRLTGMPIPLNSLRQWIIGLPGDATDYSLDDRYRLRELNYTQ
NGKTWHVTYGGYTSDTQPALPSNVELNNGAQRIKLKMDNWIVK
>Mature_203_residues
MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDEQKVYARFFWQQTGQDRYRLL
LTNPLGSTELSLTAQPGSVQLIDNKGQTYTAADAEEMIGRLTGMPIPLNSLRQWIIGLPGDATDYSLDDRYRLRELNYTQ
NGKTWHVTYGGYTSDTQPALPSNVELNNGAQRIKLKMDNWIVK

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein [H]

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family [H]

Homologues:

Organism=Escherichia coli, GI1787460, Length=201, Percent_Identity=82.089552238806, Blast_Score=355, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004565 [H]

Pfam domain/function: PF03550 LolB [H]

EC number: NA

Molecular weight: Translated: 23002; Mature: 23002

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCC
QKVYARFFWQQTGQDRYRLLLTNPLGSTELSLTAQPGSVQLIDNKGQTYTAADAEEMIGR
HHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCEEECCCHHHHHHH
LTGMPIPLNSLRQWIIGLPGDATDYSLDDRYRLRELNYTQNGKTWHVTYGGYTSDTQPAL
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCC
PSNVELNNGAQRIKLKMDNWIVK
CCCCEECCCCEEEEEECCCEECC
>Mature Secondary Structure
MNRLFRLLPLASLVLTACSLHTPQGPGKSPDSPQWRQHQQAVRSLNQFQTRGAFAYLSDE
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCC
QKVYARFFWQQTGQDRYRLLLTNPLGSTELSLTAQPGSVQLIDNKGQTYTAADAEEMIGR
HHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCEEEEEECCCCEEECCCHHHHHHH
LTGMPIPLNSLRQWIIGLPGDATDYSLDDRYRLRELNYTQNGKTWHVTYGGYTSDTQPAL
HCCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCC
PSNVELNNGAQRIKLKMDNWIVK
CCCCEECCCCEEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA