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The map label for this gene is yxnA [H]

Identifier: 152970389

GI number: 152970389

Start: 2026368

End: 2027363

Strand: Direct

Name: yxnA [H]

Synonym: KPN_01837

Alternate gene names: 152970389

Gene position: 2026368-2027363 (Clockwise)

Preceding gene: 152970387

Following gene: 152970394

Centisome position: 38.12

GC content: 62.75

Gene sequence:

>996_bases
ATGTCTGTGATGGTTATTACCGGTGGAACCGCGGGAGCGGGCAAAGCTACCGCGCTGCGTTTCGCCCGCGCTGGATATCA
CGTGGCGCTGATCGCCCGAGACGAAACGGGTTTGCAGGAGACGCGACAGGCCTGTGAACGGTTTGGCATTAAAACGCTGG
CTATTAGCGCCGATGTCGTCGATGCCGGGGCGCTGCAGCGCGCCGCCGCCGAGGTGGAAACCACCCTCGGGGCAATCGAC
GTCTGGATCAACAACGCCATGACCACCGTGCTGGCGCCCTTTCGTCAGATGAGCGAGGAGGAGTTTCGCCGGGTGACGGA
GGTGACCTATCTCGGGTACGTGAACGGCACCCGCGCGGCGCTGGAGGTCATGATCCCCCGGGATCGGGGGGTGATTATTC
AGGCCGGCTCGGCGCTGGCCTGGCGTTCAATCCCACTGCAGTCGGCTTACTGCGGAGCGAAAGCGGCGATCCGCGGCTTT
ACCGATGCCGTGCGAACCGAACTGATGCATGAGAAAAGCCACATCCAGTTGACCATGGTGCAACTGCCGGGGATGAACAC
CGCCCAGTTTGGCTGGGCGCGAAACAAAATGGATCAGGCCATGCAGCCGGTGCCCCCGGTCTATCAGCCGGAAGTCGCCG
CCGAGGCTATTTACAGCGTCATCCAGCGCCCGGTCAACGAGCTGTGGGTCGGAAAAAGCACCATCCAGTCGATCCTCGGC
CAGGTCTTCTTCCCTCGCCTGCTCGATCGGCTGATGGTGAAAAAAGCGTGGGAGGGACAGTTTACCGGTCAGCCAAAGTC
GTCAGACCAACAGGACGACCTGTTCACGCCGGTGCGCGGCAATCATCCGGGCCACGGCCCCTTTAACGATGGCGCACGGC
GTAAAGCAGTCACCATCAGCGCCGATCTCCCGGGTAAAGTCGCCGCCGGCGTCGGGGTAGCGGTGGCGACGATGGCGCTG
CGGGCGTTGTTCCGTCGTTCCGGAAAACGGCGCTAA

Upstream 100 bases:

>100_bases
TATTCCAGGATATTTCCCACCTCGTCATTGCCATTGGTGAGAAATAATTAACCGATCCGTACAGTCAATATTGTGAAAGC
CAAAACATAATGAGGTCACT

Downstream 100 bases:

>100_bases
CTCAGGCTGCGGCTGAACCAACGGTAACCATACCCGGAGAGTGCCAGCCGCGCATCTTTCCCGCCGTGCAGCCCATCCTG
ATAGAGCTTATCTTCCAGAA

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSVMVITGGTAGAGKATALRFARAGYHVALIARDETGLQETRQACERFGIKTLAISADVVDAGALQRAAAEVETTLGAID
VWINNAMTTVLAPFRQMSEEEFRRVTEVTYLGYVNGTRAALEVMIPRDRGVIIQAGSALAWRSIPLQSAYCGAKAAIRGF
TDAVRTELMHEKSHIQLTMVQLPGMNTAQFGWARNKMDQAMQPVPPVYQPEVAAEAIYSVIQRPVNELWVGKSTIQSILG
QVFFPRLLDRLMVKKAWEGQFTGQPKSSDQQDDLFTPVRGNHPGHGPFNDGARRKAVTISADLPGKVAAGVGVAVATMAL
RALFRRSGKRR

Sequences:

>Translated_331_residues
MSVMVITGGTAGAGKATALRFARAGYHVALIARDETGLQETRQACERFGIKTLAISADVVDAGALQRAAAEVETTLGAID
VWINNAMTTVLAPFRQMSEEEFRRVTEVTYLGYVNGTRAALEVMIPRDRGVIIQAGSALAWRSIPLQSAYCGAKAAIRGF
TDAVRTELMHEKSHIQLTMVQLPGMNTAQFGWARNKMDQAMQPVPPVYQPEVAAEAIYSVIQRPVNELWVGKSTIQSILG
QVFFPRLLDRLMVKKAWEGQFTGQPKSSDQQDDLFTPVRGNHPGHGPFNDGARRKAVTISADLPGKVAAGVGVAVATMAL
RALFRRSGKRR
>Mature_330_residues
SVMVITGGTAGAGKATALRFARAGYHVALIARDETGLQETRQACERFGIKTLAISADVVDAGALQRAAAEVETTLGAIDV
WINNAMTTVLAPFRQMSEEEFRRVTEVTYLGYVNGTRAALEVMIPRDRGVIIQAGSALAWRSIPLQSAYCGAKAAIRGFT
DAVRTELMHEKSHIQLTMVQLPGMNTAQFGWARNKMDQAMQPVPPVYQPEVAAEAIYSVIQRPVNELWVGKSTIQSILGQ
VFFPRLLDRLMVKKAWEGQFTGQPKSSDQQDDLFTPVRGNHPGHGPFNDGARRKAVTISADLPGKVAAGVGVAVATMALR
ALFRRSGKRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=170, Percent_Identity=32.3529411764706, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=33.8624338624339, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=28.6458333333333, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI210032110, Length=166, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI142976729, Length=259, Percent_Identity=24.7104247104247, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40807363, Length=271, Percent_Identity=25.0922509225092, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI157739938, Length=257, Percent_Identity=24.124513618677, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI32455239, Length=185, Percent_Identity=26.4864864864865, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI5031765, Length=185, Percent_Identity=26.4864864864865, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40254992, Length=176, Percent_Identity=28.4090909090909, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI38348362, Length=180, Percent_Identity=28.3333333333333, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI38424085, Length=180, Percent_Identity=28.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788459, Length=175, Percent_Identity=31.4285714285714, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=230, Percent_Identity=27.3913043478261, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786701, Length=212, Percent_Identity=27.3584905660377, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082160, Length=166, Percent_Identity=26.5060240963855, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082100, Length=181, Percent_Identity=30.3867403314917, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=165, Percent_Identity=30.9090909090909, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193203115, Length=216, Percent_Identity=24.537037037037, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=216, Percent_Identity=24.537037037037, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71997402, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=27.2373540856031, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355631, Length=188, Percent_Identity=26.063829787234, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24640492, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581726, Length=230, Percent_Identity=24.7826086956522, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356301, Length=272, Percent_Identity=25.3676470588235, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21358495, Length=177, Percent_Identity=26.5536723163842, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364892, Length=167, Percent_Identity=28.7425149700599, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI161076933, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35980; Mature: 35849

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMVITGGTAGAGKATALRFARAGYHVALIARDETGLQETRQACERFGIKTLAISADVV
CEEEEEECCCCCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHH
DAGALQRAAAEVETTLGAIDVWINNAMTTVLAPFRQMSEEEFRRVTEVTYLGYVNGTRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEECCCCCEE
LEVMIPRDRGVIIQAGSALAWRSIPLQSAYCGAKAAIRGFTDAVRTELMHEKSHIQLTMV
EEEEEECCCCEEEECCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
QLPGMNTAQFGWARNKMDQAMQPVPPVYQPEVAAEAIYSVIQRPVNELWVGKSTIQSILG
ECCCCCCHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QVFFPRLLDRLMVKKAWEGQFTGQPKSSDQQDDLFTPVRGNHPGHGPFNDGARRKAVTIS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
ADLPGKVAAGVGVAVATMALRALFRRSGKRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVMVITGGTAGAGKATALRFARAGYHVALIARDETGLQETRQACERFGIKTLAISADVV
EEEEEECCCCCCCHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCHH
DAGALQRAAAEVETTLGAIDVWINNAMTTVLAPFRQMSEEEFRRVTEVTYLGYVNGTRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEEEECCCCCEE
LEVMIPRDRGVIIQAGSALAWRSIPLQSAYCGAKAAIRGFTDAVRTELMHEKSHIQLTMV
EEEEEECCCCEEEECCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEE
QLPGMNTAQFGWARNKMDQAMQPVPPVYQPEVAAEAIYSVIQRPVNELWVGKSTIQSILG
ECCCCCCHHHCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QVFFPRLLDRLMVKKAWEGQFTGQPKSSDQQDDLFTPVRGNHPGHGPFNDGARRKAVTIS
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEE
ADLPGKVAAGVGVAVATMALRALFRRSGKRR
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]