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The map label for this gene is dat [H]

Identifier: 152970354

GI number: 152970354

Start: 1988849

End: 1990234

Strand: Direct

Name: dat [H]

Synonym: KPN_01802

Alternate gene names: 152970354

Gene position: 1988849-1990234 (Clockwise)

Preceding gene: 152970353

Following gene: 152970355

Centisome position: 37.42

GC content: 60.1

Gene sequence:

>1386_bases
ATGATGACGGATAAAGTCCGTATTGATACTTTACGTGCCGATTTATTAGACGCAAACAACGAAACCTTTTTGGCCCGTCA
GGCCGAATTCGAATCGAATGTCAGGAGTTACCCGCGTAAGCTGCCGCTGGCTATCACTAAAGCCGAAGGCGTGTGGCTGA
CGGATGCGGATAACAAACAGTACCTGGACTGCCTCGCGGGCGCCGGTACTCTCGCTCTGGGCCACAACCACCCTGATGTA
TTGCAGAGCATCCAAAGTGTCATTACCAGCGGCTTGCCGTTACATACTCTCGATCTTACCACCCCGTTAAAAGATCGCTT
CTCCGAATACCTGCTCTCTTGCCTGCCGGGCGAAGGGAAAGAATATTGCCTGCAGTTCACCGGCCCGTCCGGCGCTGACG
CCGTGGAAGCCGCGCTGAAGCTGGCGAAAAAATACACCGGTCGTACCGCGGTGATCAGCTTCTCCGGCGGCTATCACGGG
ATGACCCACGGCGCGCTGTCCGTCACCGGCAACCTGTCGCCGAAAGCGGCGGTTAACGGCATGATGCCGGAAGTCCAGTT
CATGCCTTACCCGCACCTGTATCGTTGCCCGCTGGGCATCGGCGGCGAAGCCGGCGTGAAAGCCCTGACCTACTACTTCG
AAAACCTGATCAACGACGTGGAGAGCGGCGTCCGTAAACCGGCGGCGGTGATCCTTGAAGCCGTTCAGGGCGAAGGCGGT
GTCAACCCGGCGCCGGTCGAGTGGCTGCAGCGCATCCGCAAAGTGACCGAAGAGCACGGCATTCTGCTGATCGTCGATGA
AGTGCAGGCCGGCTTTGCCCGTACCGGTAAATTCTTCGCCTTCGAGCACGCCGGTATTCAGCCGGACATCATCGTGATGT
CGAAAGCGGTTGGCGGCGGGCTGCCGCTGGCGGTGCTGGGCATTAAAAAGCAGTTCGACGCCTGGGAACCGGGTCACCAC
ACCGGCACCTTCCGCGGTAACCAGCTGGCGATGGCCACCGGCCTGACCACCCTGCGTCATCTGCGCGACAACAAGATCGC
CGACAAAGTCGCCGCCCAGGGCGAGTGGCTGAAAGGTAAACTGGCCGAGCTGCAGAAACGCTACCCGGTGATTGGCCACG
TTCGCGGTCTCGGTCTGATGATCGGTATCGAAATCGTCAAGCCGAACGAAGCGCAGGATCACATGGGCTGCTACCCGGCT
GACGGCGAACTCTCTGCCCTGCTGCAGAAGAAATGCTTCGAAGCGGGCCTGATCCTCGAGCGTGGCGGTCGTCACGGCTG
CGTGCTGCGCCTGCTGCCGTCCCTGCTGATCAGCGACGCGGAGCTGGACGTGTTCCTCGACAAATTTGAACAGGCCCTGC
TGGCCGCCGGCGTAAAACCGGTCTGA

Upstream 100 bases:

>100_bases
TAAAAAGCCATATATTGTGCGCGCTTTATGAATGCCAATTCAATTTCTTACACCAATTATTCAACCAGCGTTCAACCGCA
ATGCTGGTTGTGGGAGTGAT

Downstream 100 bases:

>100_bases
GTGGAGTAAGTGACCGCCATGTCCACATTGAATCCGATTCTTGCTGGTTCAGCGCAGAGCGTTGAAGCCTATCAGCAGGT
TATCGAGCAGACCAGCCAGG

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQYLDCLAGAGTLALGHNHPDV
LQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGGYHG
MTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVGGGLPLAVLGIKKQFDAWEPGHH
TGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGCYPA
DGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGVKPV

Sequences:

>Translated_461_residues
MMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQYLDCLAGAGTLALGHNHPDV
LQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGGYHG
MTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVGGGLPLAVLGIKKQFDAWEPGHH
TGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGCYPA
DGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGVKPV
>Mature_461_residues
MMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQYLDCLAGAGTLALGHNHPDV
LQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGKEYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGGYHG
MTHGALSVTGNLSPKAAVNGMMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
VNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVGGGLPLAVLGIKKQFDAWEPGHH
TGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGKLAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGCYPA
DGELSALLQKKCFEAGLILERGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGVKPV

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=29.4520547945205, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI37574042, Length=428, Percent_Identity=29.6728971962617, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI24119277, Length=453, Percent_Identity=28.0353200883002, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI226442705, Length=424, Percent_Identity=28.7735849056604, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI226442709, Length=397, Percent_Identity=29.7229219143577, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4557809, Length=441, Percent_Identity=24.7165532879819, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI284507298, Length=338, Percent_Identity=26.0355029585799, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI188536080, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679950, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI38679946, Length=449, Percent_Identity=25.3897550111359, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI1787560, Length=411, Percent_Identity=35.2798053527981, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=35.4761904761905, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI145693181, Length=414, Percent_Identity=31.8840579710145, Blast_Score=192, Evalue=5e-50,
Organism=Escherichia coli, GI1788044, Length=419, Percent_Identity=29.3556085918854, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789759, Length=420, Percent_Identity=30, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=30.5825242718447, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786349, Length=364, Percent_Identity=28.2967032967033, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=31.264367816092, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71992977, Length=459, Percent_Identity=27.8867102396514, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=28.433734939759, Blast_Score=144, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=329, Percent_Identity=28.8753799392097, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=446, Percent_Identity=25.3363228699552, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=439, Percent_Identity=30.751708428246, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6323470, Length=431, Percent_Identity=28.538283062645, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6321456, Length=440, Percent_Identity=25.6818181818182, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6324386, Length=489, Percent_Identity=23.3128834355828, Blast_Score=86, Evalue=9e-18,
Organism=Drosophila melanogaster, GI161085790, Length=449, Percent_Identity=30.9576837416481, Blast_Score=191, Evalue=8e-49,
Organism=Drosophila melanogaster, GI28574759, Length=449, Percent_Identity=31.1804008908686, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21357415, Length=427, Percent_Identity=26.6978922716628, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI21356575, Length=461, Percent_Identity=26.6811279826464, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281366494, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667139, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24667143, Length=445, Percent_Identity=22.4719101123595, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 49896; Mature: 49896

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQ
CCCCCEEHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHH
YLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGK
HHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCC
EYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGGYHGMTHGALSVTGNLSPKAAVNG
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHCC
MMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
CCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
VNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVGGG
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCC
LPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGK
CCEEEEEHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHCCCHHHHH
LAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGCYPADGELSALLQKKCFEAGLILE
HHHHHHCCCHHHHHCCCEEEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCEEE
RGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGVKPV
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MMTDKVRIDTLRADLLDANNETFLARQAEFESNVRSYPRKLPLAITKAEGVWLTDADNKQ
CCCCCEEHHHHHHHHHCCCCCEEEEEHHHHHHHHHHCCCCCCEEEEECCCEEEECCCCHH
YLDCLAGAGTLALGHNHPDVLQSIQSVITSGLPLHTLDLTTPLKDRFSEYLLSCLPGEGK
HHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCC
EYCLQFTGPSGADAVEAALKLAKKYTGRTAVISFSGGYHGMTHGALSVTGNLSPKAAVNG
EEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCHHHHCC
MMPEVQFMPYPHLYRCPLGIGGEAGVKALTYYFENLINDVESGVRKPAAVILEAVQGEGG
CCCCCEECCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
VNPAPVEWLQRIRKVTEEHGILLIVDEVQAGFARTGKFFAFEHAGIQPDIIVMSKAVGGG
CCCCHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCCEEEEECCCCCCCEEEEEECCCCC
LPLAVLGIKKQFDAWEPGHHTGTFRGNQLAMATGLTTLRHLRDNKIADKVAAQGEWLKGK
CCEEEEEHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHCCCHHHHH
LAELQKRYPVIGHVRGLGLMIGIEIVKPNEAQDHMGCYPADGELSALLQKKCFEAGLILE
HHHHHHCCCHHHHHCCCEEEEEEEEECCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCEEE
RGGRHGCVLRLLPSLLISDAELDVFLDKFEQALLAAGVKPV
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9260954 [H]