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The map label for this gene is yneH [H]

Identifier: 152970188

GI number: 152970188

Start: 1813446

End: 1814393

Strand: Direct

Name: yneH [H]

Synonym: KPN_01636

Alternate gene names: 152970188

Gene position: 1813446-1814393 (Clockwise)

Preceding gene: 152970187

Following gene: 152970189

Centisome position: 34.12

GC content: 60.97

Gene sequence:

>948_bases
ATGGTGGGCAAGGAGCCGCGTGTGGCGACGGTTATCAATAATGCAATGCTGGAAGCCATTCTGGCAGAAATCAGGCCGCT
GATTGGCCGCGGAAAAGTGGCGGATTATATTCCGGCGCTGGCCAGCGTCAGCGGCGACAAGCTTGGTATCGCGATCAGTA
CGGTGGACGGTCAGCACTTTGCCGCTGGCGATGCCCATGAACGTTTTTCCATCCAGTCAATCTCCAAGGTATTGAGCCTG
GTGGTGGCCATGAACCACTATCAGGAGGAGGAGATCTGGCAGCGGGTGGGGAAAGATCCTTCCGGCCAGCCCTTTAACTC
GCTTCTGCAGCTGGAGATCGAGCAGGGCAAACCGCGCAACCCGTTTATCAACGCCGGGGCACTGGTGGTCTGCGACATGC
TGCAGAGCCGGCTCAGCGCCCCGCGTCAGCGGATGCTGGAGATTGTCCGCCGTCTGAGCGGCGTGGCCGATATCGCCTAC
GATCCGGTGGTGGCTCGCTCAGAGTTTGAGCATTCGGCGCGCAACGCCGCCATCGCCTGGCTGATGAAATCCTTTGGTAA
CTTCCATAACGACGTCGCCACCGTGCTGCAGAACTATTTCCACTACTGTTCGCTGGAGATGAGCTGCGTTGAGCTGGCGC
GAACCTTTCTATTTCTCGCCGACCGCGGCATTGCCCCGCATCTCGACGCGCCGGTTATTGCGCCCATCCAGTCCCGCCAG
GTTAATGCCCTGATGATGACCAGCGGCATGTACCAGAACGCCGGTGAATTCGCCTGGCGCGTTGGCCTGCCGGCGAAATC
GGGCGTCGGCGGCGGGATCGTGGCGATTGTCCCGCAGGAGATGGCGATCGCCGTGTGGAGCCCGGAGCTTGACGACGCCG
GGAACTCGCTGGCCGGCGTGGCGATGCTGGAAAAACTGACTCAGCGGATGGGGAGGTCGGTGTTCTGA

Upstream 100 bases:

>100_bases
AGTTCTGTAATGCGCAGACCGTCTGGAAAGACCGTCGCTAATCAACGTTAGCCCCTGACGACCGTCGTCCACGTCTGCTA
TACTCGCCCACCGAATTTTG

Downstream 100 bases:

>100_bases
TGGTCGATCAGGATCGCTTGTTTGCGCGCCTGGCGCGCTCGACGTTTCGCTCACGCTTCCGTCTGGGGGGGAAAGAGCGG
CAATATTGTCTCGATAAGGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MVGKEPRVATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSL
VVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAY
DPVVARSEFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSRQ
VNALMMTSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF

Sequences:

>Translated_315_residues
MVGKEPRVATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSL
VVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAY
DPVVARSEFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSRQ
VNALMMTSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF
>Mature_315_residues
MVGKEPRVATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHFAAGDAHERFSIQSISKVLSL
VVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRNPFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAY
DPVVARSEFEHSARNAAIAWLMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSRQ
VNALMMTSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGVAMLEKLTQRMGRSVF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=280, Percent_Identity=37.8571428571429, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=34.6938775510204, Blast_Score=168, Evalue=6e-42,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=81.8181818181818, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=39.8601398601399, Blast_Score=207, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17507019, Length=285, Percent_Identity=37.5438596491228, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI193204073, Length=304, Percent_Identity=36.5131578947368, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI193204075, Length=306, Percent_Identity=36.2745098039216, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=284, Percent_Identity=35.9154929577465, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281363241, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI281363239, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI116008307, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI24653156, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24653162, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24653158, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI24653166, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24653164, Length=286, Percent_Identity=38.1118881118881, Blast_Score=194, Evalue=7e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 34287; Mature: 34287

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGKEPRVATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCC
AAGDAHERFSIQSISKVLSLVVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHEEHCCCCCCCC
PFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARSEFEHSARNAAIAW
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSRQ
HHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VNALMMTSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGV
CCCCEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHH
AMLEKLTQRMGRSVF
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MVGKEPRVATVINNAMLEAILAEIRPLIGRGKVADYIPALASVSGDKLGIAISTVDGQHF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCC
AAGDAHERFSIQSISKVLSLVVAMNHYQEEEIWQRVGKDPSGQPFNSLLQLEIEQGKPRN
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHEEHCCCCCCCC
PFINAGALVVCDMLQSRLSAPRQRMLEIVRRLSGVADIAYDPVVARSEFEHSARNAAIAW
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LMKSFGNFHNDVATVLQNYFHYCSLEMSCVELARTFLFLADRGIAPHLDAPVIAPIQSRQ
HHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
VNALMMTSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPQEMAIAVWSPELDDAGNSLAGV
CCCCEEECCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHH
AMLEKLTQRMGRSVF
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA