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The map label for this gene is murQ [H]

Identifier: 152970105

GI number: 152970105

Start: 1728521

End: 1729453

Strand: Direct

Name: murQ [H]

Synonym: KPN_01553

Alternate gene names: 152970105

Gene position: 1728521-1729453 (Clockwise)

Preceding gene: 152970104

Following gene: 152970106

Centisome position: 32.52

GC content: 63.99

Gene sequence:

>933_bases
ATGGAGGTTGTTATGAGCAGTTCGCTAACCGCGTCAATGCAGGCTCGTCGTCACCCGGAGACCACCCACATCGATCGCCT
CGCCACCGCCGATATGCTGGCGATGCTGCATCAGGATGATAAGCAGATATCGGAGGCGGTCGGCGCCTGTCTGCCGGATA
TCGCCCGGCTGATTGATATCGCCACCGCGACGATAAGCCGGGGAGGGCGCCTGGTCATTATTGGCGCCGGCGCTTCGGGC
CGGACGGCCATTGAGGCGGTCAGCGACTATTCGCCGGAAGGTAAACACGCGCTGGTGGGGCTGATTGCCGGTGGGCAGAC
GGCGGCGATGGCCGAGCGGGAGACTGCAGCGAATAATTATGACCTGGGCGCCTTTGAGCTGCAGTCGCTGGACTTCAGCA
ACCGCGATATGCTGCTGGCGCTGACCGTCAGCGGCAAGACGCCATGGGTGTGGGGGGCGATGCGCCACGCCTGGTCGCTG
GGCGCCCCGATAGCGGTCATCACCCAGCAGCCGACCAGCGAGGCGGCGCAGCTGGCGGATATCATTATTGCTCCGCAGAC
CGGGCCGGAGGCGGTGGCGGGGTTAGCCAATCCGAAGGCTCAGTTGGCCCAGAGGCAGATCGTCAATATGCTGACGACCG
GACTCGCCATCCGTGACGGTCGGGTGTACAGCAATTTGCGGGTGGACGTGCAGGCTGACAATTCGCACTGGGCGGAGCGG
CAGATAGCGATTGTGATGGCGGCCACCGATTGCACGCGCAGTGAAGCAAAGGCCGCCCTGGCCAGCTGTCATCAGCACTG
CCGCACCGCGATCCTGATGCTGCTCAGCGGGCTTGACGCCTGGCACGCGCGGGAGCTGCTAACCAAACATCACGATCATC
TGCGTCTCGCCCTGCGTGAAGCCCAGCGTAGCGCTGTCACTCCCGCCCAGTAA

Upstream 100 bases:

>100_bases
CATTCCACTTATAGTGGCGGCAGAGGTTAAATAGTCCTGATGAATATAAGGATATGCATCAGGCCGCTGATTTTGCCGAG
ATGCGCTTTTTCTGTCGTAA

Downstream 100 bases:

>100_bases
TCCCTTCTCTGCCAGGTGCGCGATGAGCATGCGCGCCTGGACTTTTGTAATTAAAGAAATTCTTAACTTTTATTTTACCC
GGCAATAGATATTGAATTTT

Product: hypothetical protein

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MEVVMSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASG
RTAIEAVSDYSPEGKHALVGLIAGGQTAAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSL
GAPIAVITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAER
QIAIVMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ

Sequences:

>Translated_310_residues
MEVVMSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASG
RTAIEAVSDYSPEGKHALVGLIAGGQTAAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSL
GAPIAVITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAER
QIAIVMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ
>Mature_310_residues
MEVVMSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDIATATISRGGRLVIIGAGASG
RTAIEAVSDYSPEGKHALVGLIAGGQTAAMAERETAANNYDLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSL
GAPIAVITQQPTSEAAQLADIIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAER
QIAIVMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALREAQRSAVTPAQ

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=281, Percent_Identity=38.4341637010676, Blast_Score=198, Evalue=4e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR000408
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33182; Mature: 33182

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVMSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDI
CCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ATATISRGGRLVIIGAGASGRTAIEAVSDYSPEGKHALVGLIAGGQTAAMAERETAANNY
HHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCC
DLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPIAVITQQPTSEAAQLAD
CCCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
IIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAER
EEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCE
QIAIVMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALRE
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AQRSAVTPAQ
HHHCCCCCCC
>Mature Secondary Structure
MEVVMSSSLTASMQARRHPETTHIDRLATADMLAMLHQDDKQISEAVGACLPDIARLIDI
CCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ATATISRGGRLVIIGAGASGRTAIEAVSDYSPEGKHALVGLIAGGQTAAMAERETAANNY
HHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHHHHCCCCC
DLGAFELQSLDFSNRDMLLALTVSGKTPWVWGAMRHAWSLGAPIAVITQQPTSEAAQLAD
CCCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
IIIAPQTGPEAVAGLANPKAQLAQRQIVNMLTTGLAIRDGRVYSNLRVDVQADNSHWAER
EEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECCEEEEEEEEEEEECCCCCCCE
QIAIVMAATDCTRSEAKAALASCHQHCRTAILMLLSGLDAWHARELLTKHHDHLRLALRE
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
AQRSAVTPAQ
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA