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The map label for this gene is mppA [H]

Identifier: 152969863

GI number: 152969863

Start: 1469821

End: 1471437

Strand: Direct

Name: mppA [H]

Synonym: KPN_01310

Alternate gene names: 152969863

Gene position: 1469821-1471437 (Clockwise)

Preceding gene: 152969861

Following gene: 152969865

Centisome position: 27.65

GC content: 58.32

Gene sequence:

>1617_bases
ATGAAGTATCCTGTCGCTTTGACATGCGGCGCGCTGTGGTTAGCCAGCGTATCTTCTCTGGCCTGGGCGGCTGACGTACC
GCCGGGCACGGTACTGGCGGAAAAACAGCTGTTAGTGCGCCATATCAAAGATGAACCCGCCTCGTTAGATCCCGCCAAAG
CGGTGGGCCTGCCGGAAATCCAGGTGATCCGCGATCTGTTTGAAGGTTTAGTCAATCAGGATGCGAAAGGCAACCTGGTT
CCAGGCGTAGCGACCCGCTGGCAGAGCAACGATAACCGCGTCTGGACCTTTACCCTGCGTGATAACGCCCGCTGGTCCGA
CGGCACGCCGGTTACCGCCGAAGATTTCGTCTATAGCTGGCAGCGTCTGGTGGATCCGAAAACCACTTCGCCGTTCGCCT
GGTTCGCGGCGCTGGCGGGGATCGCTAACGCGCAGAACATTATTGACGGCAAAGCCGCGCCGGAAACCCTGGGAGTCACC
GCCGTCGACGCCCACACCCTGCGGGTGCAGCTGGATAAACCACTGCCGTGGTTCAGCAACCTGACCGCCAGCTTTGCCTT
CTATCCGGTGCAAAAGGCGAATGTCGACAGCGGGGCGAACTGGACGCGGCCCGGCAGCCTGGTGGGCAACGGCGCCTATG
TTCTGAAAGACCGTGTGGTCAATGAGAAGCTGGTGGTGGTGCCGAACACGCACTACTGGGATAACGCCAAAACGGTGATC
CAGCAGGTCACCTTTGTGCCGATTAACCAGGAGTCCGCCGCCACCAAGCGCTATCTTGCAGGGGATATCGATATCACCGA
GTCTTTCCCGAAAAATATGTACCAGAAACTGCTGAAGGATATTCCGGGGCAGGTGTATACCCCGCCGCAGCTGGGTACCT
ACTATTACGCTTTCAATACCCAAAAGGGGCCGACGGCGGATGAGCGGGTACGCCTGGCGCTGAGCATGACCATCGATCGC
CGGGTGATGGCGGAGAAAGTATTGGGGACCGGGGAAAAACCGGCCTGGCGCTTCACGCCGGACGTGACGGCGGGCTTCAC
CCCCCAGCCGTCACAGTTTGAGAGCATGAGTCAGGCTGAGCTTAATGCCCAGGCGAAAGCCCTGCTGGCTGCCGCTGGCT
ATGGCCCGAATCGTCCGCTGAAGCTGACGCTGCTGTATAACACCTCTGAGAACCACCAGAAAATTGCCATCGCGGTGGCG
TCGATGTGGAAGAAAAACCTCGGCGTGGAAGTGAAGCTGCAGAACCAGGAGTGGAAAACCTATATCGACAGCCGTAACAC
CGGCAATTTCGACGTGATCCGCGCTTCGTGGGTAGGGGACTACAACGAGCCGTCCACCTTCCTGTCGCTGCTGACCTCCA
CCCACAGCGGAAATATCTCGCGCTTTAACGATCCGGCGTACGACAAAATCCTCGCCCAGGCGGCGGTAGAGAATTCGGCC
AAAGCGCGTAACGACGATTACAACGCGGCGGAAAAGATCATTATGGTCAAAGCGCCGATCGCGCCGATCTACCAGTACAC
TAACGGCCGATTGATTAAGCCGTGGCTGAAAGGCTACCCGATCACCAACCCGGAAGATGTGGCCTACAGCCGTACCATGT
ATATCGTGAAGCACTAA

Upstream 100 bases:

>100_bases
GCACATCAATTTTCTATCATATGTCGTTTGCAATTTCAGGTGATGAAACAAATAATTATCGCTCTGTTGGCGGTATTTTT
TTCATTTTAAAGGGGATCTT

Downstream 100 bases:

>100_bases
CCGGTACTGGTTGCCTGATGATGCCAGGCAACCATCGCTGATCCCCGAGCTGGCGCGTCTTGCCGCGCCAGTTTTTCCTG
CTCTCCTTCTCGCGCCACAG

Product: periplasmic murein tripeptide (L-Ala-gamma-D-Glut-m-DAP) permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MKYPVALTCGALWLASVSSLAWAADVPPGTVLAEKQLLVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQDAKGNLV
PGVATRWQSNDNRVWTFTLRDNARWSDGTPVTAEDFVYSWQRLVDPKTTSPFAWFAALAGIANAQNIIDGKAAPETLGVT
AVDAHTLRVQLDKPLPWFSNLTASFAFYPVQKANVDSGANWTRPGSLVGNGAYVLKDRVVNEKLVVVPNTHYWDNAKTVI
QQVTFVPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADERVRLALSMTIDR
RVMAEKVLGTGEKPAWRFTPDVTAGFTPQPSQFESMSQAELNAQAKALLAAAGYGPNRPLKLTLLYNTSENHQKIAIAVA
SMWKKNLGVEVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHSGNISRFNDPAYDKILAQAAVENSA
KARNDDYNAAEKIIMVKAPIAPIYQYTNGRLIKPWLKGYPITNPEDVAYSRTMYIVKH

Sequences:

>Translated_538_residues
MKYPVALTCGALWLASVSSLAWAADVPPGTVLAEKQLLVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQDAKGNLV
PGVATRWQSNDNRVWTFTLRDNARWSDGTPVTAEDFVYSWQRLVDPKTTSPFAWFAALAGIANAQNIIDGKAAPETLGVT
AVDAHTLRVQLDKPLPWFSNLTASFAFYPVQKANVDSGANWTRPGSLVGNGAYVLKDRVVNEKLVVVPNTHYWDNAKTVI
QQVTFVPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADERVRLALSMTIDR
RVMAEKVLGTGEKPAWRFTPDVTAGFTPQPSQFESMSQAELNAQAKALLAAAGYGPNRPLKLTLLYNTSENHQKIAIAVA
SMWKKNLGVEVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHSGNISRFNDPAYDKILAQAAVENSA
KARNDDYNAAEKIIMVKAPIAPIYQYTNGRLIKPWLKGYPITNPEDVAYSRTMYIVKH
>Mature_538_residues
MKYPVALTCGALWLASVSSLAWAADVPPGTVLAEKQLLVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQDAKGNLV
PGVATRWQSNDNRVWTFTLRDNARWSDGTPVTAEDFVYSWQRLVDPKTTSPFAWFAALAGIANAQNIIDGKAAPETLGVT
AVDAHTLRVQLDKPLPWFSNLTASFAFYPVQKANVDSGANWTRPGSLVGNGAYVLKDRVVNEKLVVVPNTHYWDNAKTVI
QQVTFVPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADERVRLALSMTIDR
RVMAEKVLGTGEKPAWRFTPDVTAGFTPQPSQFESMSQAELNAQAKALLAAAGYGPNRPLKLTLLYNTSENHQKIAIAVA
SMWKKNLGVEVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHSGNISRFNDPAYDKILAQAAVENSA
KARNDDYNAAEKIIMVKAPIAPIYQYTNGRLIKPWLKGYPITNPEDVAYSRTMYIVKH

Specific function: Essential for the uptake of the murein peptide L-alanyl- gamma-D-glutamyl-meso-diaminopimelate. Also transports some alpha- linked peptides such as Pro-Phe-Lys with low affinity. The transport is effected by the oligopeptide permease system [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI87081878, Length=538, Percent_Identity=86.8029739776952, Blast_Score=985, Evalue=0.0,
Organism=Escherichia coli, GI1787495, Length=534, Percent_Identity=48.501872659176, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1789397, Length=537, Percent_Identity=42.2718808193668, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI1787762, Length=525, Percent_Identity=28.1904761904762, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789887, Length=405, Percent_Identity=26.6666666666667, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1789966, Length=465, Percent_Identity=21.9354838709677, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59646; Mature: 59646

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPVALTCGALWLASVSSLAWAADVPPGTVLAEKQLLVRHIKDEPASLDPAKAVGLPEI
CCCCEEEHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHH
QVIRDLFEGLVNQDAKGNLVPGVATRWQSNDNRVWTFTLRDNARWSDGTPVTAEDFVYSW
HHHHHHHHHHHCCCCCCCCCCCHHHEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
QRLVDPKTTSPFAWFAALAGIANAQNIIDGKAAPETLGVTAVDAHTLRVQLDKPLPWFSN
HHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCHHHC
LTASFAFYPVQKANVDSGANWTRPGSLVGNGAYVLKDRVVNEKLVVVPNTHYWDNAKTVI
CCCCEEEEEEEECCCCCCCCCCCCCCEECCCEEEEEEECCCCEEEEECCCCCCCCHHHHH
QQVTFVPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNT
HHEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEC
QKGPTADERVRLALSMTIDRRVMAEKVLGTGEKPAWRFTPDVTAGFTPQPSQFESMSQAE
CCCCCHHHHEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH
LNAQAKALLAAAGYGPNRPLKLTLLYNTSENHQKIAIAVASMWKKNLGVEVKLQNQEWKT
HHHHHHHHHEECCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCCHHH
YIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHSGNISRFNDPAYDKILAQAAVENSA
HCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCH
KARNDDYNAAEKIIMVKAPIAPIYQYTNGRLIKPWLKGYPITNPEDVAYSRTMYIVKH
HCCCCCCCCCCEEEEEECCCCHHEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MKYPVALTCGALWLASVSSLAWAADVPPGTVLAEKQLLVRHIKDEPASLDPAKAVGLPEI
CCCCEEEHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHCCCCHH
QVIRDLFEGLVNQDAKGNLVPGVATRWQSNDNRVWTFTLRDNARWSDGTPVTAEDFVYSW
HHHHHHHHHHHCCCCCCCCCCCHHHEECCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHH
QRLVDPKTTSPFAWFAALAGIANAQNIIDGKAAPETLGVTAVDAHTLRVQLDKPLPWFSN
HHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCCCCEEEEEEEEEEEEECCCCCHHHC
LTASFAFYPVQKANVDSGANWTRPGSLVGNGAYVLKDRVVNEKLVVVPNTHYWDNAKTVI
CCCCEEEEEEEECCCCCCCCCCCCCCEECCCEEEEEEECCCCEEEEECCCCCCCCHHHHH
QQVTFVPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNT
HHEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEC
QKGPTADERVRLALSMTIDRRVMAEKVLGTGEKPAWRFTPDVTAGFTPQPSQFESMSQAE
CCCCCHHHHEEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHH
LNAQAKALLAAAGYGPNRPLKLTLLYNTSENHQKIAIAVASMWKKNLGVEVKLQNQEWKT
HHHHHHHHHEECCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCEEEEECCCCHHH
YIDSRNTGNFDVIRASWVGDYNEPSTFLSLLTSTHSGNISRFNDPAYDKILAQAAVENSA
HCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCH
KARNDDYNAAEKIIMVKAPIAPIYQYTNGRLIKPWLKGYPITNPEDVAYSRTMYIVKH
HCCCCCCCCCCEEEEEECCCCHHEEECCCEEECHHHCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9495761; 9097039; 9278503 [H]