Click here to switch to the map view.

The map label for this gene is hipO [H]

Identifier: 152969848

GI number: 152969848

Start: 1454175

End: 1455344

Strand: Direct

Name: hipO [H]

Synonym: KPN_01294

Alternate gene names: 152969848

Gene position: 1454175-1455344 (Clockwise)

Preceding gene: 152969846

Following gene: 152969849

Centisome position: 27.36

GC content: 62.74

Gene sequence:

>1170_bases
ATGACACATCCGTTGCTAGAAGCATTGCAGGTTAACGAGGCGCAATTTATTGCTCTGCGTCGTCGGTTCCACCAGCAGCC
GGAGATCGGCTTTGAAGAGCACCAGACCAGCAGCGAGGTCGCCCGACTGCTTGGCGAGTGGGGATACGAGGTTCACCGCG
GCCTGGCGGGCACCGGAGTGGTGGGCACGCTGCGCGTCGGCGAGGGGAAAAAACGCCTTGGCCTGCGGGCGGATATGGAT
GCCCTGCCGATGCAGGAGCGGAGCGGTAAGCCGTGGGCAAGCCAGGTTGAAGGGCGCTTTCACGGCTGCGGCCATGACGG
GCACACTACCACGCTGCTCTACGCAGCTGAATATCTGGCGCGCACCCGCCAGTTTACCGGCACGCTGCAGCTGATTTTCC
AGCCCGCGGAAGAGTTGCTGTACGGCGGGCGGGTAATGGTCGAGGACGGTCTCTTTGACCAGTTCCCCTGCGACGCCATC
TTCGGCCTGCACAATATGCCGGGTCAGCCGTTGGGCAAGATCGGCCTGCGCGACGGGGCGATGATGGCCTCCTCGGATAC
GCTGCATATTGAAGTGAAGGGCGTTGGCGGCCACGGCGCGGTGCCGGAGCATACGGTGGATGCCACGCTGGTGGCCTGCC
ATATTACCCTCGCGCTACAGTCCATTGTCTCGCGCAATATCACCCCGTTTGAACCGGCGGTGGTGACCGTCGGCAGCATC
CAGGCCGGTCATGCGCCCAATATCATTAACGATCACGTGCTGATGAAGCTCACGGTGCGCACCCTCAATGAGCAGGTGCG
CGAGACCGTGCTGCAGCGGATCCATGATATCGCCGTGGCCCAGGCGGAGAGCTTCAATGCCACCGCCACGCTGACCCACG
TCAACGGCAGCCCGGTGTTGCGTAACGATCCGGCGACGAACGCCATGGTGCGGGAGGTGGCGACAGCGCTGTTTGGCGCA
GAGCAGGTGGGCGAGGTGAAGCCGTTTATGGGCAGTGAAGATTTTGCCTTCATGCTGGAGCAGCACCCGCATGGCAGCTA
TTTCACCATCGGCGCTGGCGATGAGCCGGATCGCTGCATGGTGCATAACCCGGGGTATGACTTCAACGACGCGCTGTTGC
TGACCGGCGCGGCGCTGTGGTGTGGCCTGACGGAACGCTATCTGCGCTAA

Upstream 100 bases:

>100_bases
TTGATTTTTCGTCAATATAAAACAAAAAAGCGCGCCTGCAAGCTGAGCCACCCGCATAAACTCGAAAGTGTCGTGCAAAC
ACAACACAGGAATAACAAAA

Downstream 100 bases:

>100_bases
TCACGAGAAACGGGAGGGCCATGCGATGAGCACTGTCACAATAAGCGACACCCCGTTTGTCGGCAACGATCGCCTGCTGG
TGGGGATTGTGTTAAGCGTT

Product: putative amino acid amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEGKKRLGLRADMD
ALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAI
FGLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPFEPAVVTVGSI
QAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAMVREVATALFGA
EQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR

Sequences:

>Translated_389_residues
MTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEGKKRLGLRADMD
ALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAI
FGLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPFEPAVVTVGSI
QAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAMVREVATALFGA
EQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR
>Mature_388_residues
THPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGVVGTLRVGEGKKRLGLRADMDA
LPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLARTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAIF
GLHNMPGQPLGKIGLRDGAMMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPFEPAVVTVGSIQ
AGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVLRNDPATNAMVREVATALFGAE
QVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCMVHNPGYDFNDALLLTGAALWCGLTERYLR

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=381, Percent_Identity=30.1837270341207, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 42502; Mature: 42371

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGV
CCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCHHHHCCCCCCCC
VGTLRVGEGKKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLA
EEEEEECCCCHHCCCCCCCCCCCCHHCCCCCCHHHHCCCEECCCCCCCHHHHHHHHHHHH
RTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAIFGLHNMPGQPLGKIGLRDGA
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
MMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPFEPAVVTVGSI
EEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
QAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVL
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEE
RNDPATNAMVREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCM
CCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEHEEECCCCCEEEECCCCCCCEEE
VHNPGYDFNDALLLTGAALWCGLTERYLR
EECCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THPLLEALQVNEAQFIALRRRFHQQPEIGFEEHQTSSEVARLLGEWGYEVHRGLAGTGV
CCHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHCHHHHCCCCCCCC
VGTLRVGEGKKRLGLRADMDALPMQERSGKPWASQVEGRFHGCGHDGHTTTLLYAAEYLA
EEEEEECCCCHHCCCCCCCCCCCCHHCCCCCCHHHHCCCEECCCCCCCHHHHHHHHHHHH
RTRQFTGTLQLIFQPAEELLYGGRVMVEDGLFDQFPCDAIFGLHNMPGQPLGKIGLRDGA
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCC
MMASSDTLHIEVKGVGGHGAVPEHTVDATLVACHITLALQSIVSRNITPFEPAVVTVGSI
EEECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
QAGHAPNIINDHVLMKLTVRTLNEQVRETVLQRIHDIAVAQAESFNATATLTHVNGSPVL
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCEE
RNDPATNAMVREVATALFGAEQVGEVKPFMGSEDFAFMLEQHPHGSYFTIGAGDEPDRCM
CCCCCHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCEEHEEECCCCCEEEECCCCCCCEEE
VHNPGYDFNDALLLTGAALWCGLTERYLR
EECCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]